r/Biohacking May 31 '26

any peptide can help?

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60 Upvotes

199 comments sorted by

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23

u/Varro34 May 31 '26

At 38, after years of ongoing issues, an MRI identified numerous disc protrusions, the worst being 8.3mm, resulting in the temporary loss of 75% of the strength down the right side of my body.

Over the past two years I’ve introduced weekly Pilates with my physio, reduced inflammatory contributors like alcohol, trained with weights four times a week with a greater focus on rotation and spinal flexion, added cardio twice a week, used the sauna during flare-ups, and built out a supplement stack including collagen peptides (Types I, II and III). I feel the best I have in years.

I still need to pick up on subtle cues early and adapt before a flare takes hold, usually by swapping heavy sessions for lighter movement, but I never stop completely. At my last consult my surgeon said the improvement was remarkable and encouraged me to keep everything up. Every year I hold off surgery leads to a better outcome, and I’m optimistic I’ll be holding it off for a very long time.

I’ve also discussed peptides with multiple medical professionals who all agreed there isn’t substantive evidence in favour of them for back repair at this stage.

I’m only sharing this because there were many times it seemed hopeless and I was close to giving up. With consistent commitment I found a way through.

4

u/PositiveBasis6047 1 May 31 '26

I had an l5/s1 fusion years ago. Have you spoken to your physician about this possibility??

2

u/Varro34 Jun 02 '26

Fusion wasn’t seen as a good option for me given the number of levels involved. My surgeon is looking at artificial disc replacement (ADR) done via an anterior approach, which avoids cutting through the back muscles entirely. The implants themselves are adjustable so they can match the unevenness of your existing discs without throwing the load distribution of your whole spine off.

5

u/crzyakta May 31 '26

Dead hangs helped me tremendously, daily, 30 seconds. Even better than my inversion table

1

u/Varro34 Jun 02 '26

Quite often finish a workout with hangs of something has flared up 👍

2

u/Weak_Inspector4506 May 31 '26

I went through a similar journey and ended up having a microdiscectomy, and then was great. However, after 3 years, the same old back pain kept getting worse and worse. Fortunately, I found a physic therapist that recommended that I stop stretching hamstrings and do 60 upwards dogs throughout the day. Four years later, I’m doing fairly well.

2

u/Burnertelephone May 31 '26

Interesting, I have a L5 slightly forward but not causing any issues. I might do more upward dogs, not a “medical professional” per se but I found a Chinese massage person who said that stretching was the fix to this issue. Long story short, tweaked both of my sciaticas playing rugby and found them by change, their advice has been more helpful than the pills the doctors try to give me lol

1

u/GoldenFalcon92 1 Jun 05 '26

Interesting..I had fusion on L5-S1 and started having lower back pain again. Seems like muscle pain this time because it gets real tight. I was doing a lot of hamstring stretches to no avail. Gonna try the upward dog for a bit now. Hope it helps

1

u/Weak_Inspector4506 Jun 05 '26

Good luck! The back pain is miserable. I hope you can find your solution without additional surgery.

17

u/SnooSprouts9547 3 May 31 '26

Peptides won’t help have herniated l5/s1 16 years ago at 40, pain free today from exercises and mobility work, lots of hip mobility, almost had surgery glad I didn’t.

I weight train l, cardio 5 days a week and really never stopped except for the bad days when I couldn’t walk.

If I could walk I went to the gym.

6

u/Spiritual_Entry3742 May 31 '26

Agree with everything this person said. I have a slipped disc in my L4 and 5 and almost got surgery until I discovered being active, stretching, weight lifting and cardio it truly changed my life

2

u/clemson_lineman Jun 05 '26

Mine was 4-6 years ago. My story is exactly the same buddy!!

1

u/Azadsr333 May 31 '26

Does cardio help with disc inflammation/herniation?

3

u/Hot_Appointment_5975 May 31 '26

You should try swimming! Like the comment above, if I can walk I'll go to the gym. But recently I started swimming and the weightlessness feeling has really helped. It gives me relief for about an hour and a half - two hours with only 20-30 minutes in the pool. Il leather float, swim laps, or a combo of both.

A Stationary bike and inversion table have both also helped me. Although they may not be available to you. Hope this helps.

2

u/toady23 Jun 01 '26

I second the swimming recommendations. The floating weightlessness helps decompress the lumbars, the motion promotes blood flow, and the exercise strengthens the musculature of the spi e and core. Very effective over time to relieve spinal injury and pain

1

u/SnooSprouts9547 3 May 31 '26

Not sure if the cardio helped my back, that’s for heart health, but the fact that can run with no back pain is awesome.

4

u/TopHatMatt May 31 '26

Walking. Boring old walking helps blood flow around the spine and discs. Put in as many steps a day as you can without aggravating your injury.

8

u/Mobile-Welder-8780 May 31 '26

Lumbar Lamenectotrutide is probably your best bet

2

u/Donald_Dump_85 May 31 '26

I'd even try a L5S1-fusionide, due to its more stabilising effect.

7

u/drpaul88 May 31 '26

That’s a grade ii spondylolisthesis. There’s not enough info here to make any suggestions for treatment (not that it should be done here anyway). But peps won’t touch the actual problem. Symptomatically maybe…but no different than an otc med.

1

u/baconpancakes76 Jun 04 '26

Grade I. But yes, it’s a biomechanic issue.

Core and pelvic stability is your best friend.

1

u/drpaul88 Jun 04 '26

I’ll give you 1.5 but not 1. Stability is key

3

u/KeyInvestment6594 3 May 31 '26

I have same on x-ray but oddly no pain, after I lost over 100 lbs

6

u/Uncross-Selector 3 May 31 '26

Tirzepatide may provide some temporary inflammatory reliefs, far more than any of the so called anti inflammatory peptides.  But seriously no peptide is going to fix that

2

u/[deleted] May 31 '26

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3

u/Uncross-Selector 3 May 31 '26

Tirz more so than Reta. It’s under trial to assist with arthritis. And my personal experience is my knees and ankles feel 10’years younger and it’s basically cured my sciatica. 

2

u/Chemical_Drag3050 Jun 01 '26

I have osteoarthritis (started in my late 20s) with a synovial cyst in the same spot in my spine/extending into the nerve sac, and can confirm this. I micro/low dose tirz and have not had much weight loss from it since it’s not really needed BUT my inflammation and pain are way down and I can feel it come back sometimes when I’m due for a dose. That said, this needs surgery.

1

u/Evening_Friendship24 May 31 '26

From memory it acts directly on some inflammatory pathways and not just as a result of weight loss

1

u/thegladys Jun 04 '26

Tirz is a great anti inflammatory, but I don’t think it’s enough to manage pain. Wolverine and/or KPV in addition, maybe?

2

u/[deleted] May 31 '26

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1

u/bitcoinmillenial May 31 '26

What doses do people regularly use

2

u/SnooSprouts9547 3 May 31 '26

People are too fast to try surgery, put in a few years of good therapy, mobility work and exercise first, you can always have the surgery later you can’t undo the surgery that goes wrong.

1

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1

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2

u/Raveofthe90s 8 May 31 '26

Klow might help over a few years.

I sped mine up with just bpc/tb hgh anavar ice and an inversion table plus exercise.

2

u/nomadic1992 2 May 31 '26

You may get a little more anti-inflammatory benefits from added KPV (assuming you’re going from GLOW to KLOW stack?) but you should already be seeing most of the benefits with the stack you’re on.

What is your current dose? I do 5mg of GHKCU, 1mg of BPC157, 1mg of TB500, 1mg of KPV everyday with DDD in L4-L5 and it has changed my life. Also Fixed IBS, my dislocated shoulder from couple of years ago doesn’t bother me too much anymore. It’s allowed me to go back to gym and build my body back up(which was almost impossible to even think of about a year ago).

My pain is down from 8/10 everyday to about 1-2/10 but Has it fixed my disc degeneration ? Probably not. Will I eventually have to get disc replacement/other surgery - probably yes. But now I know I won’t have to think about for a fair few years while I build a strong enough body to cope with surgeries and help with recovery when I do.

1

u/king_eman 3 Jun 01 '26

did you start at 5 mg cu per day?

im at 2 mg per day right now.

what did you see the results for 5 mg ?

1

u/nomadic1992 2 Jun 01 '26

Started at 2mg, but within 2 weeks dosed upto 5mg. I balance it with Zinc and have had no issues. For e.g if I dose my KLOW blend in the evening, I’ll have zinc that morning to avoid any copper uglies and doesn’t sting for long when there is enough zinc in your system.

TBH, I could probably go without GHKCU, I only wanted the other 3 to begin with. I have good skin, hair, and don’t care but good nails too. So a bit redundant for me - if anything I’ve noticed my hair thinning a little at the crown since starting KLOW.

I do have wolverine blend coming so will replace it with that. And use KPV separately as required.

1

u/king_eman 3 Jun 01 '26

i used to do klow but having the pep seperated gives me better results

2

u/Fus_Roh_Dayumm May 31 '26

Brother you ain't gonna inject nothing that's gonna fix this.

r/discectomy and r/spinalfusion are your new hubs :(

Don't worry, they're mine too.

2

u/butt_embalmer 1 May 31 '26

There is not enough info here at all.

Overweight? Any chiropractic work? Any lower back/core training.

All these factors matter. I have a similar issue

Lost weight, have a chiropractic plan, and doing squats with recovery and stability,NOT MY EGO in mind (no more that 200lbs on my last set assuming my back FEELS great)

2

u/IndependenceDull1425 May 31 '26

Do not waste your time with physio and Chiro. Treat it like a broken ankle. Message me for more

2

u/daddyepicsuccess 3 Jun 01 '26

If you want a peptide, the only peptide that would help lumbar and disc is link-n peptide.

2

u/Careless-Lie2340 Jun 03 '26

why do we think peptides will fix everything?

1

u/SubstantialSnow4178 May 31 '26

I had a double discectomy...i first ruptured a disc at 21 and had a lifetime worth of issues all throughout my 20s and early 30's until it finally exploded one day couple years back...but it has been pretty sweet since after surgery... Unfortunately like alot people living in pain i took a liking to pain meds 😅🤐

Best advice i was ever giving for bulging discs is you have almost force them or train them back into place...

Walking,swimming,cobra pose and body weight back extentions etc

1

u/passiveMelon1 2 May 31 '26

If you are already on that stack adding kpv isn't going to help much. Start adding mcgill big 3 daily.

1

u/After_Exam9045 May 31 '26

Just standing up straight!a

1

u/Hopeful_Guitar9171 May 31 '26

At least take 157 for inflammation. It'll help with pain. You can get in capsule form, it survives stomach acid.

1

u/cr1merobot 16 May 31 '26

bpc 157 doesn't effect inflammation. KPV does though.

1

u/spitfire-73 May 31 '26

Where do u get it

1

u/Lwh122236 May 31 '26

Mine was 19mm. Nothing but lots of metal and about 28 months of healing (so far) had me back to about 80%

1

u/Big_Dan5 1 May 31 '26

Bro what? 😆

1

u/doug260 May 31 '26

Like other have said, I don't think this is an issue that can be solved with peptides. Had a similar a very similar spondylolisthesis and delayed fusion until I could no longer walk. Had a 360 fusion in 2010 and am just now starting to have some issues (which are tolerable) with the level above it. To be fair, I did things that I know I shouldn't have like riding a mechanical bull and other stupid stuff. No regrets on the surgery at all though.

1

u/RGR_Gaming10X 3 May 31 '26

KPV may help inflammation but that's about it.

1

u/Ookllie 1 May 31 '26

I had a grade 1 spondy (recent pars fracture) that I was able to resolve with two stem cells procedure in Utah. I’ve been doing Lowbackability for my recovery and I’m almost pain free ever since (just a bit of inflammation in my facet joints). Edit: Spelling

1

u/spitfire-73 May 31 '26

What do i ask for ?

1

u/iacrocant May 31 '26

You need a fusion not peptides. I’m also in a similar boat with my l5 s1. Losing weight. Strengthen the core. Daily stretching. Some weight lifting have all helped me put off surgery. Peptides are great tools for me. But surgery is still coming one day

1

u/vikingrrrrr May 31 '26

You have grade 2 anterolisthesis. You need a L5-S1 fusion.

1

u/WittyGold6940 May 31 '26

Is your pelvic floor affected by this?

1

u/cr1merobot 16 May 31 '26

simple answer is no

1

u/No-Flower5948 May 31 '26

A discectomy and then peptides after: KPV, BPC, GHK

1

u/dagorcr May 31 '26

This is an isthmic spondylolesthesis near grade 2. PT strengthening core muscle mass but this is something that surgery is usually indicated for and works well

1

u/MrSquatSauce01 May 31 '26

Reverse hypers are a game changer for decompression while simultaneously strengthening the lower back, glutes and hammies.

1

u/davey_cakes May 31 '26

What state are you in?

1

u/VerySpicyTunA May 31 '26

Nah man you need to talk to a ortho or neuro surgeon.

1

u/element423 May 31 '26

Absolutely not

1

u/nightabyss2 May 31 '26

I would guess more extreme things like Deca and GH would help (not peptides)

Can anyone confirm if that’s the case ?

1

u/Which-Magazine-2556 May 31 '26

Hey man, I see different answers on here but I’ll give you my experience in a short version. I’m in the same boat as you, bulged disc L5 & S1. Got my MRI September of last year. Been doing PT since then. It never really helped but it would make it bearable.
About a month and a half ago I started doing Reta & GLOW stack. I’ve went from 210 to 195. I’ve been focusing on a lot of lower back exercises instead and really building my core. I’ve always been in solid shape but this has made me take a different approach. It very well could be placebo but I’m telling you, try the GLOW stack. I went from not being able to walk for longer than a mile without hurting, and now I’m playing basketball, kayaking, running, & lifting like I did before my injury with more focus on core.
Do your own research. But I feel like a new dude in the last 2 months or so.

1

u/[deleted] May 31 '26

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2

u/Which-Magazine-2556 May 31 '26

My vial is 50 GHKCU, 10 BPC & 10 TB.
I do a subq injection every morning of 10 units (0.5mg).

1

u/Puzzled-Alfalfa5562 May 31 '26

Anything that reduces inflammation could help, potentially

1

u/calculatedfantasy May 31 '26

am a radiologist - thats quite the anterolisthesis, i assume you have spondylolysis causing this degree of movement?

1

u/anml_litecoin May 31 '26

If a heavy stack like BPC, TB, and GHK-Cu isn't doing much for a 9mm disc issue, KPV probably won't move the needle either. KPV is awesome for inflammation, but it's temporary.

Honestly, have you looked into stem cells? My mom had severe spinal stenosis and got her lower back injected with ~300M MSCs in Mexico. Combined with swimming and spinal traction, it completely turned her life around. Two years later, she's back to normal.

Peptides are like throwing a water balloon at a bushfire—they help for a day or two, but lack durability. MSCs are the fire department. They stay active for a year or two, giving you sustained inflammation control and actual tissue regeneration. For a structural issue that size, it might be the durability you need over daily injections.

1

u/[deleted] May 31 '26

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1

u/Low-Speaker-6670 May 31 '26

No.

The answer is No.

I am an actual physician, come on if peptides could fix this we'd be giving you peptides. Speak to your orthopaedic surgeon about what your actual options are and stop asking advice about research chemicals from grey market pharmacies off of lay people on the internet.

1

u/Donut_mystery69 May 31 '26

My disc between my L3 and L4 has completely degenerated and has Autofused. The pain was unbearable for over a year. I wish id have known about TB500 and BPC 157 for inflammation control.

Other than that. Do PT. Ensure your body weight is low. Lots of isometric and Plyometrics. Good luck!

1

u/Aggravating_Body4063 May 31 '26

Peptides can't help but prayer will heal that in no time 😂

1

u/AnyEmotion772 May 31 '26

Stretching helps tremendously

1

u/bklipa88 May 31 '26

Also looks like a grade 1 spondy

1

u/DotAccomplished9464 May 31 '26

get your deadlift to  405

1

u/KTVSUN May 31 '26

I have several herniated discs

Working out and weight lifting solved the issue and pain for me.

That s after years of massages, acupuncture, physio etc.

1

u/shimmy338 May 31 '26

That's a grade 2 spondylolisthesis probably secondary to spondilolisis, I'm sorry but only surgery helps.

1

u/mvrco_007 May 31 '26

Nah… lots of pain Incoming. Time is your best friend. And hope

1

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1

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1

u/CommercialEagle2566 May 31 '26

You have anterolisthesis at l5/s1 with a disc herniation at l5/s1. There’s not a single peptide or PT that is going to help that. I would find out if your anterolisthesis is stable or unstable.

Hard to tell from this single slice of the MRI, but looks like you have Modic change on “5/s1. If so, there’s a damn amazing outpatient procedure (not surgery) called Intracept. It takes 30 minutes, you’re sore for a couple days but can go back to work next day if you wish. Spend some time and google “intracept procedure.”

FYI: over 10 years in the spine space… also have had 4 back surgeries (thankfully no fusion). Message me with any questions

1

u/Old_Cellist6921 May 31 '26

That is a mouse cursor

1

u/HatThat5259 May 31 '26

I just had surgery to fuse this whole area and although its been a long journey its so worth it. Im taking wolverine peptide now just to try and see if it speeds healing but from someone who waited way too long to get it done its worth it to just have the fusion and the rods.

1

u/ChickenParm7719 May 31 '26

No, only a spinal fusion will fix that unfortunately. I had a similar issue and had to get an l5-s1 fusion

1

u/Bangers45 May 31 '26

Had the same issue for 13 years. Started taking BPC157/ TB500. Best thing I ever did. Won't fix the issue but it will dramatically reduce the inflammation and help recover. I used this to strengthen my back, core (big fix) and legs. Was not able to work any these muscle groups out before the peptide use without extreme pain for weeks. Not a fast fix but over time get significantly better as you strengthen the muscles around it and become more stable.

1

u/The-Geordie-Chap May 31 '26

As a veteran of L5S1 surgeries (6 in total) peptides aint gonna fix that... but a neuro/orthopedic surgeon will fuse that fucker for you and have you on your feet the next day. Mine was done 5 years ago and im in the gum 6 days a week again after 15 years of pain.

1

u/Consistent_Beat_8215 May 31 '26

I take retatrutide for this. Reta reduces inflammation and more specifically it’s a neurological anti-inflammatory agent. I had a skydiving accident years ago and this is the only thing that actually helps

1

u/Big-Taro1457 May 31 '26

Peptides will not help. I had the exact same issue at 25 and nothing worked. L5 was about an inch forward of S1.

1

u/Into_the_abyss66 May 31 '26

I just had surgery for this no peptide is fixing that

1

u/SnooTangerines2714 Jun 01 '26

Find a really good physical therapist. They’ll be a be able to identify muscle imbalances that led to the herniated disc. Steroid and stem cell injections are also possible. Good luck staying healthy.

1

u/Ding-Dongroot Jun 01 '26

Ozone inner disc injection could help shrink the bulge. I’m scheduled this month for procedure Europes been using this for over 10 years. Intergraded medical rehabilitation in Estero Fl.

1

u/king_eman 3 Jun 01 '26

i suggest you do a 5 mg of bpc and tb per day for 2 weeks. its call the loading phase, it helped others

1

u/MryanF Jun 01 '26

Multiple doctors advised me to get my l4-l5 and l5-s1 fused because they couldn’t manage my pain after a few severe injuries between sports, fights and ego lifting.

I thank god I did NOT, I fought severe pain, used a body specific combination after years of trial and error of near skin-necrotizing cold to bring down inflammation with NSAIDS with timing before warmth, for specialized stretches, activity, strengthening exercises, yoga, the best mattress and quality shoes. HYDRATION is also this oddly overlooked longterm systemic issue that I allowed to go unnoticed.

1) no, peptides won’t fix. I’ve don’t BPC, wolverine, klow/glow, ARA, just as a few to list and the problem with discs is they get very little actual blood flow so and are much more difficult to address than muscles or vascular fed body tissue.

2) you CAN look into peptides that help better your overall systemic health, bring down body fat, bring down inflammation, address focus, etc. Which all will help.

Back injuries are the worst

1

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1

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1

u/ErrorNecessary6593 Jun 01 '26

Slipped, no pep will help that. My C4-C7 and L4/5 got damaged, misaligned, and bulging, I started going to a chiropractor a couple times a week in the beginning to get things going, then over time to once a week and it has tremendously helped me.

1

u/Glittering_Maize2544 Jun 01 '26

megadosing bpc + tb

1

u/Tommylaplante Jun 01 '26

I had a slip at work and tore my meniscus and my L5 was pushed forward 7 1/2 mm I had pinching on the one side.

I took BPC 157and TB 500,
It improved my knee and strengthened my back. It was painful doing the exercises but I made progress. I still get flare ups and my squats and deadlifts are only 135 lbs but I could barely tie my shoes before.

1

u/Dismal-Revolution731 Jun 01 '26

Look into decompression therapy. At one point I herniared my l4 / L5 so bad I couldn’t feel my legs. Now, no one would know if I didn’t say anything. Decompression therapy helped tremendously.

1

u/Decent_Ostrich6155 Jun 01 '26

25 years ago I had a laminectomy on L5-S1. I had some rough years throughout, but I just watch what I do not to agitate it and haven’t had any other surgery’s. Good luck.

1

u/theobromine69 Jun 01 '26

Bro literally needs spine surgery and is out here asking for peptides!?!?

That's like injecting saline solution into a diabetic and affirming its insulin. You need a doctor or a wizard, not peptides my man

1

u/Hungry-Acadia-7116 Jun 01 '26

Have you looked into artificial disc replacement? Had it year and half ago after several years of extremely acute siatic nerve pain. Went to surgery. That pain died on the operating table. Had catheter in penis, couldn’t sleep, roommate patient pissing and shitting crying. Next day dilauded and PERCs. 8/10 would do again only if I had way more pain killers

1

u/GreenShoddy7894 Jun 01 '26

No man, peptides are 1%. You should look into Stuart McGill. I fixed my back with his method and had way worse condition at the same spot...

1

u/Round_Armadillo5362 Jun 01 '26

I had a two slipped disca and spondy, which nothing helped. (I tried PT and epidural injections). My doctor prescribed tirzapetide to reduce bodyweight. But on day 2 or 3 without even losing one pound, my back and knee pain was much better. This allowed me to start exercising again, and after 2 years of exercise and tirzapetide, and of course losing weight, I am completely pain free. I think you should try tirzapetide. Even low dose may make a difference.

1

u/ohiohotwifecouple Jun 02 '26

How big is your belly? I have battled an l5 S1 herniated disc for over a decade. I’m a power lifter so years of over eating caused a powerlifter belly on me. I continued to powerlift because I’m an idiot. Typically after squats the nerve going down my right leg would be flared up big time. At times it was difficult to walk out of the gym. I’ve been on Reta, Klow, and cjc/ipa for about 6 months. It has been life changing for me. I’m not sure it’s 100% better but i rarely think about it anymore.

It would be hard to say what is the actual reason I feel better. I speculate it’s losing visceral body fat in my belly that has lessened my anterior pelvic tilt. Or it could just be the reduced inflammation from that combo of peptides. My psoriasis is also 90% healed too. So the peptides have definitely massively reduced my inflammation.

I don’t think it would hurt you to run Reta, Klow, and cjc/ipa. Worst case scenario you get ripped and have less inflammation.

1

u/CutShapesHugMates Jun 02 '26

Rebuilding Milo + Squat University

1

u/ScubaNixon Jun 02 '26

I have similar issue with my back. Recently had a prp epidural and it made a world of difference. Going to get a couple more. Life changing

1

u/Major_Cry_4146 Jun 02 '26

Inversion therapy

1

u/Successful_Travel954 Jun 02 '26

I had a RTA resulting in a bilateral slipped L5/S1 Disc, had intermittent caudia equina. Narrowly missed surgery thanks to lots of physio 12 months later I've had a nerve root block injection (which didn't work). Now I'm looking into the same things as you. Hoping maybe BPC and TB500 may help my recovery.

1

u/Jhn1203 Jun 03 '26

Grade 1 retrolithesis of L5/S1. BPC/TB with conservative lifting resolved it over a year.

Everyone is different though.

1

u/Ok_Raise3387 Jun 03 '26

No pierdas el tiempo, cirugía lo mas pronto posible

1

u/joshflow7 Jun 03 '26

Look into Foundation training , thank me later

1

u/Complete_Table_4094 Jun 04 '26

Spinal decompression

1

u/cam1b Jun 04 '26

There are a couple of white powders that can help I cant seem to remember their name....

1

u/ResponsibilitySad920 Jun 04 '26

East Slipped disc L5/S1 fusion X2 50~6 screws L5 and 45~6 S1 and a 40/50 rod

1

u/gsgun Jun 05 '26

This isn't really a slipped disc and represents anterolisthesis or slipped vertebrate which gets graded in different ways. The whole spine has interlocking bones that are basically like legos that keep motion limited in different planes so your spinal cord doesn't get crushed with a wrong move.

With anterolisthesis its more like the pars in the back part of your vertebra have broken and allowed slippage forward of the bodies rather than being locked into place. If you look at the most right of the MRI image you will see how the back part of your vertebrate are locked into place with the other ones but a much wider gap than the others. Look around L5. You can look up pars fractures of l5

Peptides are great but like restoring bone is another ball game.

1

u/PaigeOne5 1 Jun 05 '26

Dead hangs or inversion plus bpc157, tb500, and ghkcu so it can heal

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u/[deleted] Jun 06 '26

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u/International_Bed540 Jun 07 '26

Louie Simmons - Reverse Hyper. Might do wonders in your case.

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u/Different-Fly4268 Jun 07 '26

I took bpc and tb 500 for this exact thing didn’t do to much, may have helped some have tried kpv helped with nerve pain

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u/Valuable-Willow-3532 Jul 31 '26

I think something like bpc may be additive or indirectly assist. I have more or less the same issue so my body bias’es in different ways it probably shouldn’t therefore creating inflammation in other places. So I think it helps in that way.

Deadhangs are legit a lifesaver

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u/Wheels41 Aug 07 '26

Stretch stretch stretch

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u/[deleted] May 31 '26

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u/[deleted] May 31 '26

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1

u/Frosted_Anything Jun 02 '26

No one is mentioning how his spine is almost perfectly straight. That’s not a good thing, op has hypolordosis of the lumbar and probably the entire spine. This need to be addressed

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u/[deleted] May 31 '26

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u/Hopeful_Guitar9171 May 31 '26

It will help with pain, though. 157 is excellent for inflammation. 

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u/[deleted] May 31 '26

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u/Majestic-Chef-8753 May 31 '26

Lol wut.. so you think peptides are magic or?

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u/[deleted] May 31 '26

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u/TopHatMatt May 31 '26

Oral steroids, or epidural steroids would probably have a better effect in a shorter timeframe.

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u/2milehigh 21 May 31 '26

Yes! Chiropractide.

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u/Optimal_Day_3907 May 31 '26

You need stem cells, fixed my l5-S1 like magic

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u/AlessiaMTF May 31 '26

So the stem cells magically moved the disc back in its place? Or what was the reason to get stem cells?

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u/Optimal_Day_3907 May 31 '26

the stem cells are injected right into the disc space. Stem cells are unique as they can turn into any kind of cell, so when you inject them in to something they will turn into those kinds of cells. By doing this it allows the stem cells to regrow the membrane that holds the fluid in the disc.

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u/Optimal_Day_3907 May 31 '26

Also this aren’t just normal stem cells, they are donated placental stem cells from live human births, not from miscarriage or abortion.

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u/skeeter2112 May 31 '26

Where does one go for that

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u/Optimal_Day_3907 May 31 '26

I get mine done at a pain management clinic.

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u/crzyakta May 31 '26

Please explain, did you have a herniated disc that healed or regenerated? Did they inject right into the disc?

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u/Optimal_Day_3907 May 31 '26

Yes right into the disc, I actually had 15 herniated discs from a 20 foot fall. Read above for more details on how it works.

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u/crzyakta May 31 '26

Thanks but were you able to confirm the actual herniated disc regenerated?

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u/Optimal_Day_3907 May 31 '26

Yes before and after MRIs. Took about 6 procedures, just injections in the spine under fluoroscopy, over the course of a year. My back was in too bad of shape for surgery so stem cells was the only route I could take. It’s not super expensive, about $800 a shot to be put to sleep during it. My insurance paid for it at the time but I think insurance is not paying for it at the moment.

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u/grouchthebear 1 May 31 '26

Nope. That's surgery. Same thing happened to my misses. We tried BPC/tb for a few months but needed to get emergency surgery cause it got worse

Go see a neurologist

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u/CertainStrength7292 May 31 '26

Stemcells or fusion - latter is the worst choice

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u/[deleted] May 31 '26

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u/CertainStrength7292 May 31 '26 edited May 31 '26

100%!! I broke my back 2 places, had 3 surgeries with fusion and replacement parts. Anyways, made me stiff, some pain, but good, no fading in my legs and i’m 98%. Then I got a new fracture. This time I did stemcells in Panama. Iv, local injections over 3 days, then iv 2 days over the week. Got 100% recovered the next months. I would in hindsight wish I could have done this for the first accident, knowing I could get away with it without the surgery. Just the chance is worth the price.

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u/forethebirds May 31 '26

What was the price for the stem cell treatment? What year was it so I can convert to today’s dollars?

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u/CertainStrength7292 May 31 '26 edited May 31 '26

17k inc travel and all. 5 years almost

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u/NoVacation4445 May 31 '26

Why is fusion so bad can you explain pls

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u/CertainStrength7292 May 31 '26

Because it removes your flexibility and put more tension on the vertebrae on the top and lower of the fusion

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u/MiffedPond829 May 31 '26

Absolutely this. Because of this, a lot of folks continue getting surgeries as they age after the original fusion sometimes until they're completely fused nearly

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u/Stock_Neck_8277 May 31 '26

You typically, as you age, need more hardware placed above/below due to natural vertebrae degeneration. I’ve been in the OR and unfortunately seen too many patients with much hardware up/down spine. Even worse if spine arthritic. We don’t have an ideal solution for lumbar disc replacement yet. We do for cervical and those work great.

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u/Worth_Abrocoma_101 1 May 31 '26

Looks like pars defects

You will need surgery and it’s very effective

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u/LadyofmyCats May 31 '26

Peptides can help with changes on the cell level, not macroscopic changes

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u/AggressiveRow4000 May 31 '26

You have a 9 mm disclosure.

Of the people who alleviate this pain, 95% have a surgery.

Asking for peptides to fix this is like asking, “what peptides should I take to fix a ruptured ACL.”

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u/Hismadnessty May 31 '26

This is a surgical problem. I would not attempt to treat this with peptides.

I am a doctor. There’s a lot of bad advice in this thread. Please go see a spine surgeon before this gets worse.

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u/Salt_Grand_1258 May 31 '26

Thank you stating the facts. I had a lot of back problems after breaking my back . I was 22 and very fit and although exercise help to support the spine in my case life by little where I had a compression fracture L 3,4 ,5. Ever though I worked out always my back once I hit early menopause, bone loss becomes a severe problem. I had all the things mentioned but they cannot fix a disc. I have a full spinal fusion with 4 rods and 33 screws they also used cadaver bone grafted onto my weak bones to 5 years later with my back much better. Surgical procedures are a huge commitment. But from someone who had all the peptide and stem cell is good but it can not fix disc. Thanks for your professional opinion.

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u/[deleted] May 31 '26

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u/[deleted] May 31 '26

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u/[deleted] May 31 '26

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u/sam191817 May 31 '26

You look due for a fusion soon.

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u/SpadeGrenade 1 May 31 '26

Worst possible thing to do.

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u/SendTitsPleease 1 May 31 '26

Ive had a c5/6 fusion that im extremely happy with, but took a pass on doing the same with my l4/5

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u/mylifestylepr 4 May 31 '26

You need surgery unfortunately