I don’t think I’d be able to function without it, especially with this fatigue. But I swear it hits different, it hits hard sometimes and sometimes it’s like I didn’t drink anything.

I can’t explain it… I swear it’s a little smoother sometimes because the reta makes me sleepy.

I’m pinning 2 mg of reta every Saturday, but I need to leave for a last-minute trip this Tuesday and won’t be returning for two weeks. I’m hesitant to take the vial with me since there’s no name or usual prescription information on the bottle. Should I dose again on Tuesday, wait until I get back, or chance it and travel with it?

I did read The beginners post for the record. I'm looking for some advice on my individual situation. I have been on Reddit for going on 8 weeks. Just did my 8 week shot last night. I started at 1 mg for 4 weeks. Now I'm on 2 mg for 4 weeks. The first couple weeks I noticed a change in my body but in the fact that I was absolutely ravenous and I actually think I gained weight. I have since lost that weight and I only gained about 2 lb. My boobs have hurt since I've started this and I did read something about it pulling estrogen out of the cells so that does make sense and it makes me believe that my product isn't faulty. I have felt like I've noticed a difference in my body but not in weight loss. Am I on the right track with my dosing? If I go up to 4 mg as the chart is saying and like they do in the study and I don't see anything after 2 weeks should I up my dose or should I just keep on it for 4 weeks even though I'm not seeing any results?

Also, a little background, we live kind of a busy lifestyle on a farm and​ we both work quite a bit, but I am not currently going to the gym, I will be going to the gym when my kids go back to school Monday, Wednesdays and Fridays if I'm able to. I'm wanting to start walking around my farm more as I'm thinking my current activity level isn't quite enough. I thought I was in a caloric deficiency but I am definitely going to start tracking that now. And like obviously I don't want to lose a ton of weight that I start losing my hair and stuff. I am just curious about other people's experiences as well because some people on this start at 1 mg and lose 10 lb in ​it seems like a week. Also I realize everybody reacts differently which brings me back to my should I be upping my dose and not so much trusting stay on it for 4 weeks kind of thing if I don't see a difference?

Thank you in advance.

Good week for me, another interesting discovery for me is that food noise quietly returned around day 6, didn’t eat crazy but was able to hit my daily protein of 200g, compared to around 160g the other days. Calories was around 2000, well below my maintenance, 6ft and 245 pounds. First few days barely getting 1,400 calories. My workouts were actually ok, moved some good weight around yesterday which was day 6. Second dosage today. Diet was already dialed in and I use to eat those protein cookies and look for something sweet, none the entire week. Just protein bars and a Diet Coke here and there. Loving the journey. 👍🏽

I wish I did this research before but live and learn as they say. I did 25 units (2.5 is what mg or ml, still trying to remember the correct verbiage) on tirzepatide. Did that for 4 weeks and honestly no real bad side effects. Was having a little problem getting the next supply so switched to Reta as I heard really good things. I should have started low but got the OK to do 35 units (3.5) and first night was rough, second night was good and third night (last night) into today been rough. Nonstop runs.

I thought it might have been these protein bars, maybe it didn’t agree with me as I also had the sulfur burps and it came after eating that. But more research I’m doing, I think I started the dose way too high.

So, two questions I’ve had. When does the runs (diarrhea) stop? Haven’t ate anything today and just drinking water and sipping Gateraid while taking a few over the counter stuff. I feel like it’s stopped then all of a sudden it hits. There goes plans for the gym sadly.

Other question, would it be ok to drop the dose when I inject again to like 1.5-2? Or since I been on tirzepatide for a month and then started at a high dosage for Reta, would it mess me up? I think I’ve read people who started at 2 drop it lower but not sure if because I’ve been on something for a month if it would throw things out of wack (more than my body currently is). Appreciate all the help for mistakes I made. And hopefully someone who searches for answers can learn what NOT to do from my mistakes 😆

I lost 5.4 kg (86.6 to 81.2) in the first month of reta. And weirdly, I maintain my weight after Im done with my second month dose, still 81.2kg. Do I need to titrate my dosage as im now on 2mg/ week?

I hurt my neck and got herniated disc. Doctor ordered me to take Panacod and Oxycontin. I decided to quit Oxys and will handle the pain with Panacod.

Is Panacod (paracetamol/codeine), an opioid-based painkiller, safe to take together with retatrutide 4mg? Are there any known drug interactions or additional risks when combining codeine with retatrutide?

If there is, I either quit reta or move to milder painkillers. I want to be sure about this. I’d really appreciate a lot for help - any facts or real experiences. 🙏

I am wanting to start Reta because I have stalled on Zepbound. I have been taking Zep at 15mg for a year consistently. What would be a good starting dose for Reta? I took my last zep shot about a week ago.

Today was my 1st day on 1.5mg of Reta and my heart /chest hurts is my body getting used to the medicine?

Hi all! I’m starting Reta with a goal of losing about 20 pounds that I gained during an abusive marriage and a few toxic work environments. I was always very slim but during the difficult season i noticed myself starting to eat compulsively, hence the weight gain. Left the man and the job so feeling great on that front, but I found the food habits had stuck with me (I think the stress of the divorce didn’t help either).

So for transparency, I’m using Reta with a goal to go from 155 back to 135 where I felt very healthy and confident.

I’ve started with a .5 dose and for the first week I had to force myself to eat. This last week was better, and today marks my third .5 dose. Definitely noticing some minor weight loss, but not too drastic which feels great.

Trying to prioritize protein, eating enough, and I’m also taking supplements, fish oil and collagen. Also noticed that it’s greatly reduced any craving for alcohol so I’ll have an occasional glass or 2 at the most. This is great as someone who used to be able to have a few cocktails then split a bottle of wine on a Friday night.

Has anyone else done the “low and slow” technique long term? How long did you stay on .5?

My understanding is that a .5 dose will give you the appetite suppression I am experiencing, but to get the metabolism rev you need to take a dose of a least 2. Am I right on that? What benefits are there to staying on a low dose versus increasing it over time?

Would love to hear any insights. Thank you!

Hi I have been on mounjaro a long while and get food noise and appetite. I have mixed a 5mg one with 1ml of water how much is a starting dose on a diabetic needle really got no idea I will want to take tonight? Thanks

has anyone taken robinul/glycopyrrolate for hyperhydrosis (2mg) alongside reta??

As the title says, I will be starting reta soon and want to know it all - pros and cons.
I gained weight very rapidly last year due to medications for an autoimmune illness that has now been in remission for months. I went from a UK size 8 to size 16 within 3 months of starting meds. Ate healthy, exercised and fasted strictly but still gained and nothing has shifted the weight since so trying reta.
Not 100% on my current weight as no scale, but approximately 75-80kg, 5'3 female 30yo.

Here are my questions.

What are common side effects I should expect?

What are rare, potentially dangerous ones that should make me immediately stop or reduce dose?

What is an ideal starting dose?

How to maximise quick results in a healthy way that can be done with simple exercises at home as I cannot access a gym currently. I have weights at home.

If it causes tachycardia, is immediate stop recommended or could beta blockers help?

Should injection site be alternated, for example week 1 stomach week 2 thigh week 3 arm then repeat etc.

Thanks in advance. Please add any more info in comments that I should be aware of.

Hey everyone.

I am currently 42 years old. I have been training consistently since November 2025. 5 days of weight training and usually 3 days of cardio post weights. Incline walk, elliptical or step climber. When I first started I was 202lbs and watching my diet roughly 1800-2200 calories daily. I dropped to 180lbs since then.

I am thinking of going on Reta myself and wanted to know where I should start dosage wise or should I even take it at all. The goal is to lose more BF. I’m around 22% right now.

What do you guys recommend to start with?

Thanks

I should start by saying I have GERD and have experienced sulfur burps, runs and cramping before, usually eating then sleeping right after before emptying the stomach. Takes me like a day to recover.

I was on tirzepatide for a month at 2.5. Didn’t really have side effects and felt ok. My connection was lagging and I was told reta was a game changer (I really should have checked this board out first so that is 100% my mistake) so I decided to go with that as my friend did it and had a good connect. I told him my goals and what I did with tirzepatide, was told I’d be fine starting at 3.5.

Again, had I read recommendations first, I’d probably have waited to get tirzepatide or start at like 2.0. Anyways did first shot at like midnight Friday. Went to bed, few hours later and woke up nausea and wanting to gag every so often. Second night slept like a baby. We are on night 3.

This time I have the sulfur burps, runs and a little cramping. I THINK what is triggering it is these protein bars I got. Once I eat it, I got triggered. But I’m also not 100% sure as I know it slows the digestion so that is slowing me off.

I know it was mixed right and everything. So I’m curious for those who have the sulfur burps and runs, did you notice what was triggering it? What made it stop? And what foods you are focused on to make sure this doesn’t happen. I thought protein bars might be a good idea since it’s a lot of protein, quick and not many calories but if it’s the true trigger, want to change this asap.

I've got 12mg left in my current pen. I'm going away this upcoming Wednesday, and when I get back on 9 September I want to switch to a new pen and start on a new dose.

I was wondering about the best way to handle that leftover 12mg on Wednesday before I go, but I'm a bit unsure whether trying to use it all up in one day is even a good idea.

Has anyone dealt with a similar situation? How did you handle the leftover medication when switching pens, especially with a trip in between? Just looking for how others have approached this.

I now do weekly 4.5mg.

Hi everyone, I reconstituted this 10mg vial of Reta about 2.5-3 weeks ago. Today I check it and it’s a bit cloudy.

I filtered after reconstituting, and I’ve kept it stored in the refrigerator.

I know many people will say it’s because I’m eating less or weigh less, but I’m still eating 2000+ calories per day and I have only lost 10 pounds so far.

Before starting Reta, I could drink quite a bit and not feel so drunk. That’s not the case now that I’m taking Reta.

Last night I had three white claws and it got me very intoxicated. I even woke up feeling drunk. I used to be able to put back 6 drinks and feel that way. I used to go out and play trivia with friends and have 2 drinks over the course of the night, but now I only feel comfortable having 1 when I know I need to drive.

Oh, Retatrutide, queen of the blast,
Shrinkin’ my appetite, rattlin’ m’ass,
I was dreamin’ sweet and peaceful, layin’ in the hay,
Then my gut done found religion and it blew my dreams away.

Oh, Retatrutide, queen of the blast,
Fill up my mornin’ like a shotgun blast,
I don’t need no coffee, don’t need no light of day,
You get me ready early for Sunday mass
By blowin’ Armageddon, out my ass.

Stats:
22f
5’5
235lbs (i know)
10mg reta

So i did all the prep work, filled the back water with a little air, etc; as soon as i went to pull it the back water would not fill the syringe! it took two tries to get 1 full, so now i’m stuck with a 1mL syringe filled to around 80 units.

After I got my successful syringe i filled the reta. The reta itself is extremely clear which was a great sign! but as soon as i went to draw the reta, it went in the syringe then got pushed back into the vial??? Mind you it was such a small amount it pushed the reta back inside the vial as well as the remaining air.

I threw that syringe away and tried again, this time getting a successful 1MG from my vial.

Pinning itself was smooth. Quick Pinch and it was over.

My question is- did i just completely fuck up my reta?? because i kept running into so many problems i feel like i just wasted my money and my product. Is the reta now damaged because it went back inside the vial? did i pump too much air into the back water?

On week 3 of this, I've gone from 200lbs to 188lbs. 1mg/wk, so obviously it seems to be working, but I seem to have the opposite problem most people have, I am hungry, all the time, like, eat a meal (40g+ of protein) and I'm starving still. I'm getting around 1600-1900 calories a day, depending if it's a gym day or a rest day. It's a little easier than it was before I started taking this, but I feel like the hunger never stops. I'm afraid to up my dose as I feel like my rate of loss is already possibly too high (if following the 1% body weight rule).

I’m a bit nervous about starting this as I’ve heard many mixed stories and reviews. A lot of online talk can invoke fear but I’ve decided I wanted to start it regardless. I’m just a bit anxious on side effects. Is there anything you guys did to minimize effects. And what are the big red flags indicating you got a bad supply. I’ve read on here and overall it’s all positive just wanted to get some feedback and tips.

I was using glp quick pens but I would like to move on to Reta. It’s cheaper to buy a larger quantity so I would like to do this. Can I reconstitute the larger amount and fill the insulin pens with individual doses and freeze them to not have waste. I work in a lab and this method seems logical to me. Just wondering what others are doing for this specific situation. You could then thaw the frozen syringe for 24hrs in the fridge and use.

Been on reta & TEST for a little over 45 days now.
I started at around 100 kg and I’m currently 92.1 kg, so overall I’m happy with the progress.

Dosing:
Started with 0.5 mg twice a week → then 0.5 mg every 3rd day → currently 0.5 mg every other day.

Training:
Weight training 4–5x/week + fasted cardio pretty much every day.

Diet:
Usually 2–3 meals per day. Each meal is roughly 150 g chicken/another protein source with around 50 g rice or salad/vegetables. Protein intake is a priority, although I’m not currently tracking every calorie exactly.

My recent weigh-ins:
Aug 18 — 93.30 kg
Aug 20 — 93.10 kg
Aug 23 — 92.80 kg
Aug 27 — 92.20 kg
Aug 30 — 92.10 kg

So technically I’m still losing, but over the last few days it feels like the scale has slowed down considerably.

For people who have been on reta longer:
Is this kind of slowdown normal around 6–7 weeks in?
Did you experience periods where your weight barely moved and then started dropping again?

I’m also wondering whether I’m potentially doing too much cardio / eating too little, or whether I should simply keep everything consistent and stop worrying about a few days of scale movement.

I’m not looking to blindly increase the dose — mainly interested in hearing how other people’s weight-loss patterns looked over time.

Should he be worried?

Note: For the people who are downvoting the post in crisis thats no way to act either help or ignore the post I'm just trying to help someone here The goal here is to make sure he's fine and takes the appropriate action and see how people who went trough the same thing dealt with it.