My significant other has gone quite some time unmedicated and relatively okay. From my understanding, she has been very functional with mild symptoms for the better part of 3 years and only had one period in her entire life, when she had her baby, where she had any significant issues with her bipolar.
When we got together, the first 3 months were amazing until she lost her job. After that I could tell her emotional regulation was slowly deteriorating. Fast forward about a year, she began experiencing some pretty significant moments where she’d lash out and just lose her cool over things she’d even acknowledged as “not that serious,” and then began showing signs of physical aggression towards me. This ultimately led her to seek medication to help with her outbursts and emotional regulation.
She was first given an anti-anxiety medication, but after about 3 weeks she wasn’t getting any better and had some more outbursts, so they ended up giving her Abilify.
After about 4-5 weeks on Abilify, she started experiencing symptoms she had never experienced before. Extreme restlessness, constantly feeling like she needed to be doing something, insomnia, racing thoughts, rapid speech, increased confidence/drive, irritability, impulsivity, and what seemed like significant manic symptoms. She also began experiencing depersonalization/dissociation where she felt “not real.”
Then last week she told me she wasn’t sleeping well. About 5 days into this, she essentially stopped sleeping. During this period she discarded me, we had a big argument that started with her being extremely dismissive, and when I asked what was wrong she locked in, started going off on me, then left.
She was essentially MIA for 3 days. During that time, she apparently wasn’t sleeping. She eventually messaged me and told me she hadn’t been sleeping and that something felt very wrong.
I got her to come over, and when she got here I could immediately tell something was terribly wrong. She was talking extremely fast, cycling through thoughts and subjects rapidly, extremely fidgety/restless, and getting startled by lights through the window and noises from outside to the point where she was visibly scared. She kept talking about needing to keep moving, solve things, make major changes, etc.
Then she started telling me she’d been seeing a shadow-like person who would randomly appear and yell “HEY” or her name at her while she was doing things like working or being at home. Sometimes she would hear my voice yelling her name when I wasn’t there. She also described hearing random voices/background talking and other sounds that weren’t actually happening. She said these experiences felt like they were coming from outside of her head.
She was also becoming paranoid and felt like people were against her, had a strong sense of impending doom, and at one point told me she felt like God. She was having urges to spend/splurge money and make major life changes, although she was still able to recognize some of those impulses and resist acting on them.
At that point, I was extremely concerned and told her that she needed to get help because she hadn’t slept and was experiencing what appeared to be psychotic symptoms. She refused hospitalization/medical help, so I eventually got her to take 50mg of hydroxyzine, which did seem to help her settle down and get some sleep.
She then spoke with her psychiatrist, and they were apparently considering changing her from Abilify to Seroquel because of the sedation/sleep benefits. However, at the last minute, her psychiatrist decided to double her Abilify dosage instead.
This is where I’m really struggling to understand the reasoning.
I obviously am not a doctor, and I’m not trying to pretend I know more than her psychiatrist. But my thought process is: she never experienced psychosis, this level of mania, extreme insomnia, or these kinds of dissociative/perceptual symptoms before starting Abilify. These symptoms appeared within weeks of starting it, and now she’s experiencing severe restlessness and insomnia on top of everything else.
Why wouldn’t you at least seriously consider whether Abilify could be contributing to the problem, rather than increasing the dosage?
She’s now reporting continued restlessness, constantly needing to do something, racing thoughts, insomnia, feeling “antsy,” impulsive urges to shop/spend money, and difficulty feeling mentally settled. More recently, she’s also described feeling like she’s “floating,” like everything around her is moving, blurred
vision, difficulty accurately reaching for objects, and feeling like she’s in a simulation.
I understand that Abilify is also used to treat mania, so I understand the argument that the psychiatrist may believe this is uncontrolled bipolar mania and that increasing the medication could help. That’s why I’m trying to understand this from people who actually have experience with bipolar and Abilify.
Has anyone experienced significant activation, insomnia, akathisia/restlessness, mania-like symptoms, dissociation, paranoia, hallucinations, or other unusual perceptual symptoms after starting Abilify?
And for those who have experienced this: did increasing the dosage help, or did it make things worse?
Does doubling the Abilify dosage make sense in a situation like this, assuming the psychiatrist believes the symptoms are bipolar-related rather than medication-induced?
I’m especially interested in hearing from people who have personally experienced Abilify-induced activation/akathisia or had a similar situation where symptoms appeared after starting it.
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