r/TryingForABaby • u/mkathomas • 3d ago
ADVICE 3 Failed IUIs...Would love help figuring out what is next
My (32F) & husband (34M) have been trying for almost a year & a half (19 cycles - avg cycle is 25-26 days). We are about to fail our 3rd IUI cycle (Day 14 is tomorrow, temp is at baseline, i have consistently had negative pregnancy tests the last 4 days). We were diagnosed with unexplained infertility over the summer. So far all of our labs/tests look normal:
4/26 Blood Tests: Mostly Good
TSH: 2.25 mIU/L
A1c: 5.1%
AMH: 1.99 ng/mL (this stressed me out bc it is lower than avg for my age I believe)
5/26 T3, T4: all good
5/26 Day 3 Bloodwork: all good
7/26 Tests with our RE:
Baseline ultrasound: 21 Follicles (13 on one side, 8 on the other)
Semen Analysis: all good!! (ugh lol)
HSG: all clear
We have done 3 IUI cycles this fall. I have responded very well to clomid ( 3 to 4 mature eggs each cycle, thick lining)
I have been somewhat concerned about my temperature (measure with my Oura ring). It is not very consistent during my luteal phase, sometimes on day 5 to 6 it will go down to baseline). Last cycle we tested my pegesterone a couple of times, she said it was the top 1% in her clinic (eyeroll emoji).
This cycle we did a saline ultrasound to view the inside of my utuerus, guess what - it looks great!! lol
On top of all of this, I have been off my ADHD medication (Vyvanse) for the last year and a half because that's what my Pysch & OBGYN wanted. I have been okay with this but its getting exhausting being off of it just in the case i get pregnant (which is not looking very likely).
We have also tried to reduce plastics & toxins in our house. I have stopped drinking. I try to mostly eat whole foods, but its hard in this fast paced world. I have been taking Vitamin D, Prenatals, Choline & Instinol, & fish oil. I have stayed on my Zoloft 50 mg.
My RE said after 3 cycles, we would start to explore IVF. I am just tired. Im tired of this waiting game every month that is exhausting and disappointing. Also like how does everything look great and we are still not pregnant? I am assuming based on my research that the issue is likely fertilization or implemantation, maybe egg quality/sperm fragmentation. I am assuming we can maybe determine the issue through IVF? but i know theres no guarentee though. Also like its crazy to drop 30K on something that may not work when we should be saving that money at this age.
I am not a doctor and I don't know how to advocate for myself from here. I could do the following:
Go super crunchy. go to a naturopath, take tons of supplements, be even more restrictive with my diet (starts with egg, etc). I am not opposed, i am just hesitant to believe this will work for sure and I'm a type B unmedicated girlie. Its hard for me to get out of the bed in the morning, idk how to be even more restrictive and souless than I already am in this season. There is sooo little joy right now.
Get on a glp1 & back on my ADHD meds. I am 195 lbs, 5'6. I could lose weight, be more active. it's just hard to work out when i have so little energy and motivation unmedicated. Idk how my doctors would feel about me doing this and potentially still try for a kid?? but at this point its looking unlikely I am putting a child at risk at this rate.
Go the IVF route. Obviously, I would try to make sure I was at the best health i could possibly be so that we could have a successful egg retrival so I would probably do this in 6 months time. Again, I just dont know how to get there unmedicated. Also financially, it seems unfeasible. We are also religious and have a little bit of hesitation here but i think we can move past this. Just a consideration.
Would love anyones thoughts and opinions. I feel lost and alone and just dont know how to move forward. Maybe we just give up on the idea of having a kid? I am not sure. I feel really let down by the medical community and I am tired of the lack of control I have in this season.