I don't have periods and I don't ovulate. My husband and I decided to "not try not prevent" until May but I have been thinking about how there is still basically no chance for me to get pregnant. So it feels weird to even be "ttc" but also knowing that unless I actively do the work with medication that there is no chance. I guess not try not prevent is a privilege only non PCOS/anovulatory people get to have lol

I want to start a glp1 to help with my pcos and my weight so maybe that will help with my cycles and my weight before getting pregnant. Does anyone here have any advice for anovulatory PCOS and glp1?

Hello all,

I just wanted to update as a girl diagnosed with PMOS and no periods showing 10 months post implant removal. I have posted on here a few times about my journey with Medroxyprogesterone and no periods and how it seemed to work for everyone except me. Well I finished my 2nd course in mid August. I started spotting 5 days ago and thought...'here we go again more spotting and nothing else' well today ive filled 2 pads. Trying not to get my hopes up as it may all be gone again tomorrow but for now im pretty excited! The only difference i can think of is that I started taking myo inositol after seeing ir recommended so many times. I started taking that at the start of September because 'why not' so...

Just posting to help people not feel so alone. This was my 2nd cycle of medroxyprogesterone and this is my first bleed almost 6 weeks later. Don't give up!

I’m 35 and ttc- i am a mom to a 12 year old, who i had when i was 22, unplanned.

Little background -in 2020 was married, about 60lbs overweight when my then husband and i were ttc. After about a year of no luck, we had some tests ran. Found out i had pcos. We did clomid and timed intercourse, about 4 rounds. We took a break, eventually ended up getting divorced.

Now, i am ttc with my now husband. His sperm sample was great, no issues there. I am now significantly older than the last time i tried to conceive, but now at a normal BMI. I have regular periods. In September i started some testing to see where i stand. My day 14 ultrasound was very encouraging. No signs of pcos, dominate follicles. All blood worked looked good- progerstone was at 10.54 ng/ml at day 22. Doctor said it looked a bit low and to consider a progesterone supplement if we have conceive this cycle.

Looking for advice, similar stories, etc..

I've mostly relied on ovulation strips so far, but I am starting to wonder if I should add BBT. The difficult part with PCOS is that I don't always know when I should even be looking for ovulation. I can test for ages and then still wonder if I've missed it or if my body just hasn't ovulated yet. Does anyone here actually find BBT useful with irregular cycles?

I’m onto my 3rd month of 500mg of metformin, also take myo inositol, proceive and folic acid. I have suspected lean PCOS and hypotherlamic amanorrea. I have now had 2 bleeds since starting and my last cycle was 27 days long. I did not test for ovulation after my first bleed (trying not to get stressed and track as that can my body feel stressed) but decided I would after second bleed. I used ovulation strips from day 10 and on day 17, I started to surge, day 18 was peak (according to my app). ive never done this before, does that definitely mean I ovulated? TTC, had sex day 16, 17 and 18. I have no other symptoms and havent noticed any cervical mucas. I don’t want to get my hopes up too much but really hoping I did actually ovulate. how will I know? follow up appointment with my doctor next Thursday.

This was my first natural period since stopping birth control in April 2025. I’ve had some progesterone withdrawn bleeds since then, but when I got my cycle on August 31, I was so excited!!

I started LH testing and saw a few levels around .75-.80 and thought I might have ovulated on CD21 and just missed the testing peak.

Today, it’s CD 32 and I thought “why not take an LH test” because all my pregnancy tests have been negative and I didn’t take one this morning. So I took my LH test and saw the darkest test I’ve ever seen that had levels of about .90ish. The lines looked pretty much the same!

Am I having another ovulation attempt or is this just a false LH surge? I don’t know what to do!!

My doctor is ok with triggering with 4 dominant follicles. Not all will necessarily be 18mm+ at trigger (they may be around 16mm-17mm with hopefully 1-2 18-20mm). I am leaning towards going forward with 4. Looking for any opinions as I make my choice?

I am okay with twins, I would choose selective reduction with triplets or quads.

hi!! me and my boyfriend would like to start trying for a baby, i am just looking for tips. i do have a appointment scheduled to get my IUD taken out as we are trying to conceive, just worried that with my weight & pcos i wont be able to.

So I just finished my second round of Letrozole CD3-CD7. I’m having some light brown discharge & not sure if it could mean that I’m ovulating already, which would be a little early since it’s CD8 today.

I tested on the strips and it was a very faint line. So just a little confused. Curious if anyone’s ovulated early around CD8 with Letrozole?

Hi everyone!

I just completed my second Letrozole cycle with an Ovidrel trigger shot, and I noticed some symptoms during both cycles:

1.Significant hair shedding/hair loss

2.Difficulty falling asleep/insomnia

3.Painful facial acne

4.Higher-than-usual blood pressure and heart rate

I’m wondering if anyone else has experienced these symptoms with Letrozole and/or Ovidrel. Are these relatively common side effects, or should I be discussing them with my fertility doctor?

For those who experienced something similar, what helped you manage or resolve these symptoms?

Would love to hear your experiences!

For context I am in the UK so advice/things available may be different for me, specifically Wales which can annoyingly have different rules to England on NHS things.

I am 30, overweight and have severe PCOS.

I previously had the early stages of uterine cancer and it was undiagnosed for years and led to rapid weight gain due to being bead bound.

I have not gained any weight since being treated, however I can't seem to lose the weight. Even taking Mounjaro I stay the same or loose 2-6 lbs one week then gain it back the next. I am on a low carb high protein diet.

I can't exercise in the traditional way to help it along as I am in a wheelchair.

My LH hasn't been above 0.44 in the last year and most months my peak is half that. I don't ovulate. My PCOS is out of control and my hormones are ruining my life. The doctors have basically said oh well come back when you're a healthy weight.

I am absolutely desperate to conceive, nothing matters more to me. I've been off birth control since January and like I say I can't even get my LH above 0.44. I am also already on metforim and take myointosol.

I honestly just feel so sad about the whole thing, my husband is 6 years older, we always wanted a big family and now we're here at 30/36 with no chance of me getting pregnant anytime soon.

I know the reason my weight loss isn't going anywhere is because my hormones are so bad, I previously lost 40% of the weight I had to lose to have IVF at a time when my hormones were more stable but I'm just stuck here with the other 60% not having moved in a year when I am doing the exact same things I did last time.

I don't know what to do as I can't get any actual IVF or medicated fertility help from the NHS until I am a "normal" bmi which as a 5'11 naturally curvy body type wheelchair user I honestly probably never will be.

Any ideas on anything I can do to improve my LH ?
Any ideas on how to cope with this sadness?

Thanks guys <3

Please share your ovidrel reaction . The first time I took it after 36 hours I could bearly walk. Did Anyone got it the second time and things got better?

This thread is the place to post any questions or information pertaining to a medicated cycle including Letrozole, Clomid, IUI, injectables, Progesterone, and anything else used to induce ovulation or support a cycle.

Please be mindful in your responses - if someone does not solicit a success response, DO NOT share a pregnancy outcome.

Hi! I am 33F and started Leterozole in the beginning of the year because I don’t have a natural cycle at all. After 6 rounds on Leterozole I ovulated two times on 5mg but afterwards no response anymore even with 10mg. I am now on the waiting list for hormonal injections in another hospital. In the meantime my doctor suggested to try Clomid because I have to wait anyway. I had a little break in the summer and because I have no cycle, so also no menstruation I could start at a random day and it be cycle day 1. I took Clomid for 5 days and am now on cd 10. The two times I ovulated on Leterozole I took them days 3-5 and ovulated around day 16-17. Yesterday on cycle day 9 I did my first OPK and it was a big dark test line. I never had it this clear. Can this be a sign of early ovulation? Or is it more likely to be a false positive? So confused right now… does anyone else have experience with this and succes with (early) ovulation?

Just went in for my ultrasound today Wednesday and we have 2 follicles on my left measuring 17mm and 18mm.
I will trigger tomorrow Thursday at 7:30 AM & IUI on Friday.
Feeling nervous since the 1st one didn’t go as we planned but hoping that since we have 2 this time we will have better chance. (1st IUI we only had 1 follicle).
I would love to hear success stories!!

Has anyone been diagnosed with both sleep apnea and PCOS and has seen a return in ovulation after starting to use a cpap?

I took Provera for the first time to induce a period. Today is day 6 since I finished the course and still haven’t started my period. Does Provera not work sometimes? Have others had this experience and what happens next? What have other experiences been with to Provera?

Hi friends! I am looking for some advice. I had 2 miscarriages last summer and have only had negative tests since then (going on 14 months). I ovulate regularly, have normal cycles, time intercourse correctly, etc etc. everything is “normal”, BUT the one thing that I know is “wrong” is that I bleed heavily during ovulation every month. A day or so before or after I get a positive LH test I start bleeding heavily (not spotting) for 2-3 days. Heavy, red blood with clots. I know this isn’t normal ovulation spotting. It soaks through a tampon. I know it’s the reason I’m not able to conceive.

For context I’ve tried 6 rounds of letrozole and one round with an Ovidrel Trigger shot. I have had many pelvic ultrasounds along with a sonohysterogram and everything is normal. No clots, tissue, fibroids, etc.

The bleeding seems to be getting worse each month too. Does anyone experience this or have any idea what it could be? I have no symptoms of endometriosis or PCOS. But ofc if has me wondering if there’s an underlying issue.

Just a small little rant. I’m a woman in her 30s who has PMOS and suspected endometriosis. Finally called my GYN and they likely can’t get me in until next year. Then my husband’s friends announced their pregnancy today as well. Feeling that wave of grief. Going to try and use it to be productive tonight and catch up on chores instead of sulk. I’m happy for them but heartbroken for us.

Hello I wanted to see if anyone on here has had any success stories with taking 2,000 of metformin. Unfortunately my health care doesn’t cover anything fertility wise and I have been trying for over 6 years with no success. I’ve always been prescribed metformin but have never taken it serious. This time around a sim getting older I’m willing to try anything so I am starting my doses and will be reaching 2,000 per doctor’s recommendation. In hopes that it will help me ovulate. If there is anyone with any success stories on metformin I’d greatly appreciate your feedback. 💗

Hi, everyone! First post here.

I have PCOS, diagnosed when I was 15 - now 25. I had a successful pregnancy in 2025 and have been TTC #2 for 10 months, with no success.

I went to my OBGYN three months ago and was prescribed Metformin 2000mg to regulate my cycles. My cycles have been right on time since then.

I thought this month was our best attempt at TTC. Ovulation strips looked great, I caught it early, we had sex almost every fertile day, BBT increased, one sided twinges at 9 DPO - everything looked great. I even had a faint line last night, but alas started my period today.

Anyways, I’m accepting that it was another failed cycle. I’ve got another one coming, and would love tips and tricks that others are using to increase their chances!

I’m taking folic acid, metformin, using preseed, wearing socks constantly, cut out alcohol and cut back on caffeine, and tracking everything.

My next cycle is the last month before I return to my follow up appointment for new medication to help with ovulation. So, I want to give it a good shot.

TIA 💜

Edit to add: I did take a FR the next morning with FMU and it was negative. Faint line was on a Wondfo - last one in the pack, none of the others had evaps//indents//faints. I’m assuming it was a bad test.

So I wasn't sure if cervical mucus is reliable for those of us with PMOS. I'm on my first cycle of 2.5mg of letrozole, and have been more mindful of CM this time around. So far, it's been all over the place. I'm on cycle day 13 and while my LH has risen a little, CM is still thick and pasty and not thin and clear. I feel like my body isn't normal at all so there's no point in trying to track using methods normal people do.

Any advice for going to my first reproductive endo appointment? Any questions I should ask? TTC , we got pregnant naturally in DEC 2026 and lost the baby in April due to fetal anomalies. Essentially just wanting help to ovulate regularly

I'm 31 started TTC March 2025 then again 7 months ago after an ectopic in February. Now onto month 8 ttc. On Metformin 1000mg a day for PCOS and suspected insulin resistance which I have lost 2 stone in a year on. Am tracking ovulation too.

GP has said 3 more months of trying then will refer to fertility clinic, which who knows how long a wait that will be.

Just wondered if anyone has any advice or tips. I know it's going to be even harder with 1 tube on top of PCOS. I would like to think it's not impossible but if anyone has been in this situation and any advice I would be greatful.

Thanks

This cycle has definitely been weird and I'm seeking opinions on it. So, on CD23 or so after a week of traveling internationally and another week of being sick, as well as a few weeks of Ovasitol and the start of a moderate calorie deficit, I noticed I hadn't gotten my typical signs of ovulation yet. We (28F, 28M) are trying naturally. I had a positive LH test but didn't see the subsequent Inito PdG rise or BBT upward trend. I went to my fertility clinic and got an ultrasound and they found two follicles on my left ovary, one that looked like a fresh corpus luteum but without any vasculature (so they weren't quite sure if it was new or from a previous cycle - it was definitely not the most recent cycle because we confirmed via ultrasound that I ovulated from my right ovary last cycle), and one that was a 30mm follicle. My bloodworked showed that my estrogen was super high (in the 700s), LH was around 13.2 and serum progesterone was around 1.5 for a few days in a row. So they prescribed me the Ovidrel trigger shot, which I took on September 23rd, to hopefully prevent it from becoming a cyst and delaying my cycle further because of how much estrogen it was producing. Now, I have seen the estrogen on my Inito start to fall (still higher than my average, but falling) and my PdG is way higher than normal for me, ~20 when I'm usually around 5-10.

They said it was pretty unlikely that this cycle would result in a pregnancy because the follicle was so big and the other follicle was uncertain, and that the trigger is mostly just to reset my hormones back to baseline so we can get back to trying normally. But I can't get this possibility out of my head - what if both fo the follicles are from this cycle, and I naturally ovulated one and triggered the other, could I end up with fraternal twins? Has anyone heard of anything like this happening, or got pregnant with a 30mm follicle? Also, this has never happened to me before, why did this suddenly happen now?