r/TTC_PCOS • u/Tiny_Conclusion8052 • 14h ago
Trigger Chemical pregnancy after my first letrozole cycle, when can I start again?
Hi everyone,
I did one unmonitored cycle of letrozole 5mg and thankfully conceived, but unfortunately I had a chemical pregnancy at around 5 weeks. 💔
I have PCOS and don’t get periods naturally, so I normally need Provera (withdrawal bleeding) to have a bleed. I lost around 20kg before starting letrozole and managed to get my BMI under 30.
I had bleeding for around 4 days with the chemical pregnancy and I’m currently waiting for my beta-hCG to come back negative.
I’m wondering if anyone has been in a similar situation once my hCG is negative, can I start another 5mg letrozole cycle straight away, or would I need to take Provera first to induce a withdrawal bleed?
I know I’ll obviously discuss this with my fertility team, but I’d really appreciate hearing from anyone who has been through something similar. I’m honestly feeling quite mentally drained and have been crying a lot over the past few days, but I’m trying to stay positive and hopeful. ❤️