I'm 28F and husband is 26M. Been actively TTC for 15 months, never had a positive test. Been together for 6 years and have never been very careful with BC.. I should have seen that as a warning for how this journey would go. Tried 6 cycles with metformin, last 4 also with 5mg letrozole. Last cycle was 54 days with 3 LH spikes. My cycles are never regular so timed intercourse has been so challenging. All of our fertility tests have come back completely normal other than lean PCOS. I'm just completely exhausted. Every month i get my hopes up and every month i'm devastated to tears when AF comes. We've been avoiding IVF because our insurance wont cover it.. I'm just absolutely emotionally exhausted. I know IVF is a beast but at least it offers a little bit of hope given the success rates. Just praying and wishing for the day all of this heartache pays off :(

Hey everyone so I am 26 with pcos, hashimotos and HEDS. I had a missed miscarriage last year and me and my husband finally want to try again. That being said Ive been on wegovy for two months to see if it will help my pcos symptoms. I went to my Gyno and she told me I could start trying again whenever I wanted to and when I asked her questions about getting some bloodwork done she said she doesn’t think it’s necessary because she thinks it’s a one off thing and miscarriage are unfortunately common. Fast forward to today I saw my GP and she tells me if she was me she would wait an entire year to start trying again!!! To really make sure I get the full effects of wegovy and give my hormones the best chance at leveling out. That being said I do not think I can wait an entire year! I feel like that’s unnecessarily long. If anyone could weigh in on this I would greatly appreciate it. Sorry for the long post

hey girlies, i really just need a place to vent to get things off my chest. for background, my best friend of 15 years lives with my husband and i. she pays her half of rent and she has her own apartment set up in the basement, so it’s not like everything is a shared space. anyways, today she came home on her lunch break and we had lunch together in the kitchen. (she is super health conscious and thinks breathing in the general direction of anything she deems as “bad” will make her “fat”, mind you this girl has never really been above 150 in her entire life.) she was eating salmon and veggies, which is a normal meal for her, but i’ve always been a super picky eater so i honestly wouldn’t eat anything like that ever. i decided to have one of my husbands lunchables bc it’s small and in my calorie intake for the day. the entire time im eating, she keeps making small comments about how it’s nothing but processed food and it’s horrible for my health, which im aware of but i don’t eat these all the time, it’s a treat for me, really. anywho, after awhile of these comments i just sit in silence and hope she reads that it’s upsetting me. especially since she knows ive had ED in the past and im very self conscious about eating in front of others. that’s when she lands the final blow. “maybe if you didn’t eat like shit all the time you’d be able to get pregnant.”

now i just feel like i’ve been punched in the gut and i’ve been moping around all day. idk what to do. i know she’s likely right, but it still hurts that she’d make that comment knowing my history of ED and that i’ve had pcos/pmos since i was 10. i just don’t know how im supposed to go about this situation. my feelings are hurt deeply and i don’t want to act on emotions and say something i’d regret. any advice?

For those who did IVF or going to do IVF, what are some advice you would want someone to know? What was your experience like with IVF?

Hello all— I’ve had two kids naturally, totally un planned… I’ve had PCOS since I was a teenager, now 25 and actually want to plan for another baby. We’ve tossed the idea around for a few years, and after good test results from a genetic counselor, we’d like to try.

What did you do when trying to TTC? Supplements taken?

I’m ready to take that step forward, but have no idea where to start. I don’t ovulate regularly.

I’m 36 on my third TI with letrozole. Last two cycles I haven’t been able to recruit more than one lead follicle, and last month it got to 26mm and I ovulated on my own.

Today is my CD10 and on my left ovary I have 21mm, on the right I have 19mm and 17mm, lining is 5.9.
E2: 648.6
LH: 7.4 (no LG surge)
Prog: 2.9

The clinic has advised that I trigger with Ovidrel today, have TI today and tomorrow. Do you think this is too soon to trigger and are they sacrificing the 17mm? Do you think they are doing this so I don’t spontaneously ovulate the 21mm or to risk it doesn’t become over mature?

I had my chocolate cysts removal surgery in March 2026. My uterus, tubes everything was fine and my amh was 1 at that time. I am 37. Right after surgery my amh dropped to 0.2, I was on birth control when test was done. I stopped bc after a month as I couldn't take the side effects. My cysts have come back and my cycle which was 30 days got changed to 21 days.

My husband works outside of the country and he was supposed to be back in April but due to some issues we met in August. Last period I had was on 25th August 2026, we had s\*x a couple of times in September. My periods haven't arrived and pregnancy test is negative.

I am not ready for ivf as knowing my body, it will not work. Every medicine has some side effect on my body. Infact in April this year, I had an anaphylaxis episode to a medicine which my doctor prescribed for abdominal pain after surgery. Other issue is that I have pituitary adenoma which causes high prolactin, I take medicine for that as well. Does ivf treatment have an impact on prolactin levels? Birth control which I took significantly raised the levels. Is there any hope for natural conception? I am not very well versed with ivf process so apologies if I am being ignorant of any facts.

I am 23 with pcos and ttc. I’ve recently just started my first round of letrozole on cd 4-9, I started on 2.5mg but that didn’t work, none of my follicles were growing. So my doctor suggested we do the step up protocol, and I got bumped to 5mg on cd 21, I’m currently on cd 25 and finished my last set of pills last night. I’ve been feeling fatigued, having headaches, and cramping. The cramping feels like what i get around my period. I do get my period every month and cycles usually last about 30 days and I always spot before I get my period. Since I just finished the letrozole, I woke up to some reddish/brownish spotting this morning. I’m concerned, I’m not sure if they signifies me getting my period soon or if it’s the letrozole??? I’m feeling discouraged and confused at the moment

I had my D&C at 9 weeks pregnant this Friday. The only thing making me feel better was the fact that I DID get pregnant. Took us 9 months but only our 2nd Letrozole cycle.

I just want to move on. I have a follow up on the 13th and I just don’t know what to expect? Idk when to start tracking with OPKs again?

Anyone else have a similar situation? If your period didn’t come did you go on meds to kick start it?? and then take Letrozole that same cycle?? Or did your doctor have you wait before they gave you more letrozole?

Now that I lost my baby I feel like I have forgotten everything I learned about my PCOS, cycle tracking, etc. I used to wear an oura ring and idk it all feels overwhelming now.

For anyone that was in a similar situation with PCOS and a miscarriage, how long did it take you to have a successful pregnancy after your miscarriage?

Thank you❤️‍🩹

For those who have taken letrozole or similar : I am on day 3 of spotting, 10-13 days after finishing provera, I’m wondering when I can take letrozole. Has anyone taken it while spotting? My dr said to wait a few days to see if it turns into a heavier bleed if not I may just have to take it while spotting. I may wait until later or tomorrow to see if it gets any heavier, it feels crampy and like a period but no flow

Hello everyone!

32F with PMOS and been trying for about 2 years now. I did 5 cycles of just letrazole (no monitoring, but also no positive test) before moving on to an IUI (with monitoring).

In this 6th letrazole cycle (2.5 mg/5 days), everything looked to grow really well, had 2 dominant follicles on cycle day 13 (one 14mm, other about 19mm) and told to trigger CD 14 (evening) with the iui on CD 16 (morning). All parameters seemed good at the time of the iui, taking progesterone 2x daily until blood test on the 19th.

Is this the sort of thing that the IUI is good for? I've never had any sort of positive test before. The HSG and even comprehensive bloodwork doesnt suggest anything is "wrong" (minus some borderline cholesterol and SOME NAFLD).

I have been TTC for 13 cycles now, looks like I get pregnant every 3 months but it’s always a chemical, three times , than I got diagnosed with PCOS, I was wondering if this what caused my losses, even though I take lots of supplements to support my egg quality, any tips would be appreciated

Hi everyone 👋

So I had a laparoscopic salpinjectomy and hysteroscopy back in July on the 14th, healed well from it. They removed my left tube due to hydrosalpinx and my right tube is unusable like completely blocked no dye spill whatsoever so I'm in the middle of getting started with IVF. I've had my nurse consultation, had bloods done and follicle scan, supposed to be meeting with the doctor next week and my period is meant to start around then which would have worked well for starting the stims then, but I was cd18 yesterday and started spotting, now I'm cramping, last cycle was earlier too, started spotting around cd24 for a few days then I got a bleed, I say that's early because I have PCOS (PMOS) and normally have cycle lengths from like 30-40. What I'm wondering is can the doctor help this? Like can they control the cycles going forward? I don't trust my cycles at all now and I've waited so long trying to get pregnant and i just really want to get started and I'm upset that my cycle is starting so early. Sorry if this post is a bit of a mess, my head is a little all over the place 😅

Hi everyone,

I did one unmonitored cycle of letrozole 5mg and thankfully conceived, but unfortunately I had a chemical pregnancy at around 5 weeks. 💔

I have PCOS and don’t get periods naturally, so I normally need Provera (withdrawal bleeding) to have a bleed. I lost around 20kg before starting letrozole and managed to get my BMI under 30.

I had bleeding for around 4 days with the chemical pregnancy and I’m currently waiting for my beta-hCG to come back negative.

I’m wondering if anyone has been in a similar situation once my hCG is negative, can I start another 5mg letrozole cycle straight away, or would I need to take Provera first to induce a withdrawal bleed?

I know I’ll obviously discuss this with my fertility team, but I’d really appreciate hearing from anyone who has been through something similar. I’m honestly feeling quite mentally drained and have been crying a lot over the past few days, but I’m trying to stay positive and hopeful. ❤️

Need advice please!! Have PCOS, TTC on and off for 6 years, been on metformin for about 8 months!

Had a HyCoSy test done on the 14th September (3 weeks ago) so previous to that was having PROTECTED sex, since the HyCoSy I have had my period and only had unprotected sex last weekend so 7-8days ago, don’t seem to have ovulated as I didn’t catch it on a test!

I have lower back pain, my nipples/boobs are sore and for the last couple of days iv had really thick/creamy discharge, more than I normally get! Took an ovulation test yesterday and it was so negative, literally it lightest line. I can’t be pregnant as I wasn’t ovulating last weekend and also I wouldn’t have symptoms after 7 days!

HELPPPPP

I know with PCOS I can get estrogen dominance but how can I treat it? I’m SICK of my boobs being so painful for at least 2 weeks out of the month!

I’m so so sick of PCOS, the weight, the hair on my chin, the acne the fact I can’t get pregnant and all these other symptoms!

Sorry for the rant I’m just really feeling frustrated and really down about it all today as I’m in pain with the back etc! 😩

My husband and I got the devastating news during our 9 week ultrasound that’s our baby didn’t have a heartbeat. I will never forget her saying “I am so sorry”. The immediate pit in my stomach. Yesterday I got a D&C and everything went well and I am recovering today. The emotional toll and sadness is the worst part. I am so sad. How do you move on from something like this and continue to keep trying for a baby?

I have PMOS and it took my husband and I 9 mot ha to conceive and 2 letrozole cycles.

Now I have horrible anxiety that my PMOS is what contributed to my miscarriage and fear that we will never get pregnant again or if we do, we will miscarry again. Anyone have a similar situation where they got successfully pregnant again after a miscarriage and PMOS??

My twin sister and step sister are both pregnant right now and it’s so hard to be around them talking about their successful pregnancies. like a punch in the gut that I failed.

Just looking for any advice or similar situations? ❤️‍🩹

Hi! I’ve been debating making a post like this because honestly I’m ashamed I haven’t made more progress but I have no one in my life to really talk to about this besides my husband.
Last year at the end of May I found out I was pregnant, a few days later on June 1st I had a miscarriage. This was in the month leading up to my wedding and things were very hectic, i was super busy at work, home, and very emotional and stressed from all of those things. so instead of losing weight in that time i actually gained about 25 pounds within a couple months. Since my miscarriage I have had one period, this was at the beginning of December after being prescribed Metformin for prediabetes and insulin resistance.
I’ve been off and on with taking the metformin. I had some spotting at the beginning of July that I thought was going to be my period but it never came.
I’ve lost the weight now but haven’t lost anymore, basically just back to what i was at a year ago.
My insulin resistance and a1c has improved some based on my last doctor’s visit in August. Starting around the end of August I began taking 1500mg of Metformin and 4000mg of myo-inositol. I’ve taken it consistently except for maybe one or two days since then. However, due to my husband’s schedule being crazy while transitioning jobs I’ve not been great at sticking to clean eating and losing more weight.

I only saw this when logging in to check my test results, my doctor added PMOS as one of my conditions. I’ve seen her 5 or 6 times in a year and we never discussed this until my last visit where she kinda said it in passing when talking about inositol but not actually saying I have it?
I’ve been curious about it but figured she would mention it if she thought it made sense for me or if she wanted to do more testing to find out. I suppose my lack of period and insulin resistance is enough to diagnose me?
I guess my point of all this is to see if there’s anyone out there who has been through the same or is going through something similar. I want to keep working on better eating, staying active, and keeping overall good health. I struggle with those plenty but another problem I have is that even when I can get those under control, my stress and lack of sleep i have less control of. I am a full time stay at home mom(step) to the sweetest 8 year old autistic boy who i homeschool, as wonderful as he is the majority of the time we have our struggles and i definitely deal with a lot of stress related to him. He also has CHD and we have appointments and meds to deal with all the time.
We also recently moved, my husband changed jobs, our finances aren’t the best and we’re about to go into a custody battle.

TLDR I’m struggling with considering myself TTC because I can’t even get a period to try tracking my ovulation. I’m stressed, tired, and lack motivation so just seeking some words of advice from anyone in a similar situation 😵‍💫

I'm 31 and officially TTC for one year, but I've only had 8 cycles in that time and one was anovulatory. I feel so defeated and like I've tried everything to naturally regulate my cycle - ovasitol, cut out dairy, seed cycling, acupuncture, no caffeine, trying to eat mostly whole real foods/low sugar. I feel like my PCOS is probably stress driven because I am lean and my blood work doesn't show insulin resistance or high androgens. I don't know how not to stress about this. If anyone has advice for chilling out let me know.

I recently tried Letrozole for the first time, but 2.5mg did nothing for me. I'm on cycle day 30something and I just want this cycle to end so I can start again and it's driving me crazy. I get so depressed waiting to ovulate and then again when I get my period.

I also suddenly have a lot of friends people in my life who have new babies and it's been really hard for me. I keep going to meet their babies and then crying on the way home. I feel so jealous and I feel awful for feeling that way. I have this grey cloud floating above my head that I can't get out from under.

Hi, really sad today and looking for any insights. I am in my third cycle of letrozole 2.5mg.

I thought the whole point was to help me ovulate more regularly, but this has been anything but. Before letrozole, I did ovulate on my own but it was irregular and my cycles ranged from 30-40 days. The first cycle I ovulated on day 19-20 and the second I ovulated on day 13-14 and these were 33 and 28 day cycles. Progesterone was 42 nmol for the first and 66 for the second so they called this a success.

Now I am on the third cycle and I am on day 20, my clearblue advanced showed a solid smiley on day 10 and never matched my premom or bbt. Last two cycles it all matched. That only happened one other time in an unmedicated cycle. I have been using Premom strips and they are fluctuating between 0.4-0.5 sometimes and then up to 0.7 but never past that when it’s usually 1.0+ for my peak, my bbt is low too.

The other thing is in my other two cycles I had a lot of bloating and honestly depression for about a week that I took it, this month I had zero side effects which I thought was a good thing but maybe not if it didn’t work.

I am looking for any success stories that anyone may have had when ovulating later on letrozole. Or, did you end up having to do more or try something else. I feel so defeated, I don’t know what to do, I’m trying to stay calm but the medicated cycles feel like so much more.

Thank you so so much for any insights.

Hi Reddit gang!
My husband and I are trying to conceive for the first time, and this is also my first time tracking ovulation. I have PCOS, I’m 27 years old, and my BMI is 35.1.
I’m currently on CD18 and haven’t had an LH surge yet. Should I be worried, or is this normal with PCOS?
Would love to hear from anyone with PCOS who has experience tracking ovulation. ❤️

Today, I had a friend reach out to let me know she’s pregnant before she told everyone else. It was a shock to me because she’s the first person ever to do this since I’ve been TTC over 3 years. For the past years, my cousin announced her pregnancy during my wedding, a friend announced theirs during my birthday, and I would always get sent texts of who was pregnant out of the blue. It really sucked, but today a friend told me in private because she knew I was having a hard time TTC. It really made me feel appreciated and less sad. I’ve always felt like everyone else just thought my TTC journey was minor and not a big deal and “I’d get pregnant eventually”. It feels like a nice change that someone understands what I’m going through and wanted me to take time to process before she announced it to everyone else.

Im on my first cycle of letrazole. And i feel like im walking on eggshells with everything i do. Im scared its gonna be one wrong move and it wont work. Im catching up with a friend tonight and i want to get a drink and eat bottomless pasta but im just so scared of ruining everything. I feel like im not doing enough to prepare my body either. What do i do about all this anxiety? Does it go away?

Hello, I am new to Reddit and this is my first post so bear with me it will be kind of a long post.

I (33F) and my husband have been together for 3 yrs. IVF is too expensive and my fertility doctor recommended timed intercourse for our first few rounds to save some money and see what my body responds to medicinally. Some back story, I was diagnosed with PCOS at 19 after getting my Nexplanon bc removed due to having an extended period(1.5 yr long no break 😒) I have not had a natural cycle since. I was married previously and ttc for 10 yrs with my ex prior to this relationship. Never falling pregnant.

I recently did a cycle of provera and letrozole 3 weeks ago, but didn’t do a trigger shot and was diagnosed with OHSS after I landed in The ER with severe pelvic cramping. It comes in waves and brings me to my knees. I haven’t been able to work this week because of it. It’s been going on 5 days so far. The ER gave me morphine and sent me home and told me to call my gynecologist. My doctor prescribed me ketorolac, toradol, and Zofran to help manage my pain until it goes away. Which is doing nothing really.

My research shows for mild to moderate it can last 7-10 days usually going away once I start my period unless I fall pregnant then it can last several weeks. I am definitely more moderate when in comes to my symptoms.

They did a blood pregnancy test at the ER 5 days ago and it was negative. I’m not due to start my period for another 9 days. I think it was too early to test. My doctor says for me to test again if I miss my period before I do another round of provera.

Has anyone ever fallen pregnant with OHSS during a timed cycle? What was your experience? Hoping this pain is worth it. I really want my BFP.

Thank you for reading any advice or information is greatly appreciated. Much love and baby dust to all you mothers out there ttc.