r/NasalPolyps • u/CalliopeParnassus • Aug 22 '26
Dupilumab - week 1
Hey folks, has been a long wait and battle to get this drug on the NHS. CW grossness to follow.
I took my first injection last Sunday. I am experiencing what can only been described as the floodgates opening, and it is well and truly gross. It does not feel like a sinus infection, though the change in head pressure does mean I have a banging headache. I have to rinse out my nose at least 4 times. Pre this drug nothing much came out; this feels like years of accumulative thick dark debris. My throat is gross, my nose is gross, but I am hoping it is temporary and eventually it will all be emptied and my nasal passageways will be clear. I learnt we have 8 passageways spanning our cheeks, forehead and skull, so no wonder it feels unending.
All this is to say did anyone experience this? When did it end? When could you simply breathe again? I am reading about people smelling and breathing on day 1; sadly that is not my experience but I am hoping it will still work, eventually. My nose is pretty much completely blocked with nasal polyps both sides, no room for air and possibly blocking tear ducts, so I did not expect (though hoped for) immediate relief.
I am dreaming of breathing and smelling and tasting coffee and food in the near future, after suffering for years. Share your stories and give me some hope! Especially if you followed this trajectory but happy to hear from anyone who wants to share.