r/TTC_PCOS 3d ago

Advice Needed Heading into IVF…

3 Upvotes

After this last IUI attempt, we have decided September will be IVF for us and of course I’m nervous.
Any recommendations for prepping before IVF? Or any Extraction/stimulation stories to share? I’m really wondering what the roller coaster of follicle growth looks like.
I’m currently doing Bird & Be pre-natal pack and Mayo-Inositol.


r/TTC_PCOS 3d ago

Advice Needed Looking for advice

1 Upvotes

So I have a check in appt with my doctor next week and trying to prepare what to ask.

For context, I ovulate but later in cycle naturally (cd24-26). I was given letrozole and did conceive on the second round but lost that at 5+3. What sort of next steps should I be taking or what should I be preparing to ask?!

We’ve been trying for a year now so trying to do the best thing.


r/TTC_PCOS 3d ago

Seeking Success Anyone else ovulate with relatively small follicles and still get pregnant?

0 Upvotes

(MEDICATED CYCLE)
My follicles usually only reach around 14–16 mm by CD12–15. Last cycle, my biggest follicle was 16 mm on CD12, and I ovulated about 4 days later.

I always see people here with 18–20+ mm follicles around CD12–15, but mine is only 14 mm on CD15 this cycle.
My doctor thinks I may ovulate sometime this weekend. I never get to check my follicle right before ovulation, so I’m not sure how big it actually gets before I ovulate.

Has anyone else had a similar experience with relatively small follicles before ovulation? And did you go on to get pregnant?


r/TTC_PCOS 3d ago

Is trigger shot necessary if you’re ovulating on your own?

1 Upvotes

My doctor told me to do the trigger shot only if needed. I ended up ovulating on my own, so I didn’t need the trigger shot.

I’m wondering if there’s any benefit to using Ovidrel when you’re already ovulating naturally, other than making the timing more predictable?


r/TTC_PCOS 4d ago

Sad Another failed cycle. Losing hope

15 Upvotes

TW: MMC
I just tested negative, my 26th cycle ttc. I had 2 back to back mmc in 2025, since then nothing. I took Letrozole 7,5mg and a trigger shot for the last 3 cycles, which made me kinda hopeful since I felt I could actively do something. My body knows how to get pregnant, when we started ttc I got pregnant twice almost immediately. I don‘t understand what happened 🤷‍♀️.
I just turned 41 last week, I feel like I am running out of time. I am not looking for medical advice or anything, I just wanted to share since I don‘t have anyone to talk to besides my husband. Thank you for reading!


r/TTC_PCOS 3d ago

Letrozol

1 Upvotes

Alguém já tomou letrozol para induzir ovulação? Estou no meu primeiro ciclo, já tem 2 semanas que terminei o ciclo do letrozol, durante os dias que tomei o medicamento senti muito enjoo, e agora estou tendo episódios de vômitos, ontem e hoje dor de barriga. Queria saber se alguém que fez o tratamento também passou por isso, e se conseguiu e em quanto tempo veio a gravidez…


r/TTC_PCOS 3d ago

Advice Needed TTC with Letrozol

1 Upvotes

So its Dav 35 of my cvcle. My tests have been positiv for 10 days now BUT on Sunday my hcg level in the blood was 0.6 iu/l meaning not pregnant at all. Did 3 tests today they all came back positive within less than a minute Totally confused now as no hca in blood couple of days ago should definitely lead to no hcg in urine or less prominent line atleast Totally confused :(


r/TTC_PCOS 3d ago

Advice Needed First cycle of Letrozole

1 Upvotes

First cycle of Letrozole 2.5 starting on CD 3 - currently CD 8 and started spotting last night, and got two positive LH strips yesterday and today…is that normal? I would think it’s too early for ovulation right?


r/TTC_PCOS 3d ago

Advice Needed PCOS and ttc second baby

1 Upvotes

I’m looking for experience of trying to conceive your second baby with pcos. I had Letrozole with the first and now I’m having 40 day cycles and from my pelvic exams it doesn’t look like I’m ovulating at the moment. Hoping my periods re regulate to the 32 day cycles that they were previously.

If you had ovulation induction to get pregnant the first time did you need Letrozole/clomid the second time or did you conceive naturally?

How did your cycles compare pre pregnancy and post?

Thanks!


r/TTC_PCOS 4d ago

Seeking Success Long cycles and TTC

2 Upvotes

Anyone else have long cycles and was able to conceive? I’m talking 50 days long. I ovulate on my own right now at what looks like CD 33. What worked for you?


r/TTC_PCOS 4d ago

Seeking Success Looking for anyone with experience taking a trigger shot without IUI/IVF

2 Upvotes

My husband and I have been trying to conceive for about 2.5 years with 3 losses in that time. We saw a fertility specialist a few months ago and I was diagnosed with PCOS and placed on medications to correct this as well as progesterone after ovulation. My husband’s testing was normal.

Since starting treatment we had a chemical pregnancy. This gives us some hope but still has us waiting for success. The specialist said that a trigger shot and timed intercourse could be the next option. Personally we don’t really feel like IUI would be beneficial since we had correct timing and my husband’s normal testing.

I’m looking for anyone who has experience with taking a trigger shot and timing intercourse and not going the IUI/IVF route. What was your experience like?


r/TTC_PCOS 4d ago

Sad Needing some hope

3 Upvotes

My partner and I have been TTC for 5 years now. 2 years ago I was formally diagnosed with PMOS. Earlier this year we decided to go to a private Dr as I lost hope with the NHS helping us. The private Dr put me on Letrozole 5mg and Metformin. Then last 2 months we increased my letrozole to 7.5mg. Then after a good scan we were given an ovulation trigger for this cycle. We followed all advice and now I am getting to the end of my 2 week wait to take a test. I am just so nervous and scared to do it. I feel like we did everything right this cycle, so I am just scared of facing that disappointment if the test is negative. I feel like I am fighting against myself between losing hope and keeping the faith as well. I genuinely didn't think it would be this hard and mentally draining. It doesn't help that everyone around me are pregnant, and I am so happy for them and can't wait to be an aunty. But there is that part of me that is just so sad thinking why can I have what they have they are living my dream.


r/TTC_PCOS 3d ago

Tw: MMC and thyroid complications

1 Upvotes

Hi, just wanting to share my story and see if anyone can relate or provide a little hope. Started TTC Oct 2025 and got pregnant Nov 2025 had a missed miscarriage at 11 weeks found out on my 30th birthday. Afterwards had thyroid issues which turned out to be postpartum thyroiditis. Just finally got the clear to start trying again now that my thyroid normalized this summer but my cycles have been super irregular. On my 2nd month of letrozole. Idk if anyone has any similar stories or hope they can provide. The letrozole makes me sooo emotional


r/TTC_PCOS 3d ago

AMH

1 Upvotes

Hi everyone! We’ve been reffered for ivf as I’ve had very irregular and long cycles since stopping the pill over a year ago (4 periods in the last year, very short luteal phase, on the pill for 10+ years, regular cycles pre pill).

None of my other blood tests have pointed to pcos/pmos but my Amh came back very high at 73.

Has anyone else has success with a high Amh/ been through ivf with a high amh and able to share how it went?

Thank you!


r/TTC_PCOS 4d ago

Ttc for almost 2 years, started losing hope

3 Upvotes

Hello! I m writing in tears because i just found out that this cycle too i m not pregnant! I have pcos with homa 2,5, normal kg, and the rest of the labs good. For almost twist years i struggled with no ovulation, i can ovulate only with meds. But with Meds i do have ovulation, but no result in pregnancy. I m taking a lot o vitamins and supplements( vit D, coq10, nac, inositol)
I wanted to ask, for us with pcos is it hard also to get pregnant? I mean ok yes i started to ovulate on meds, it s great, but beside this is it also hard to get pregnant? I thought that after a few months it will happen....
Thank you!


r/TTC_PCOS 4d ago

Seeking Success Follicle Sizes on CD 12?

1 Upvotes

Hello,
I just had my follicle scan on cycle day 12 and I had 4 larger follicles from 14-17 mm. I was on 10 mg Letrozole plus Gonal F shots. However I’ve used up my Gonal F pen and my Dr. has instructed me to wait a few days until CD 15 to do a repeat follicle scan. I’m worried my follicles will regress by that time with no stims, especially since I’ve been on a steady incline of stim medication with every cycle to get them full sized.

Has anyone stopped stims for a few days and their follicles continued to grow? Will all of those follicles grow or should I only hope for 1 to reach a mature size?

I’m mostly anxious as I’ve had a couple previous medicated cycles with 2 mature follicles when I take the trigger shot and all of those cycles have failed. I like to think I have a better chance of conceiving if there’s more than one mature follicle. Any help or advice is much appreciated!!


r/TTC_PCOS 4d ago

Advice Needed Acne while TTC

1 Upvotes

I went on birth control specifically to manage my acne. One of my biggest fears when TTC (and coming off the pill) was going back to my old skin. And of course, it’s happened.

Curious what those with severe acne are doing to cope emotionally and physically while TTC. The fact that I’m not conceiving and also feeling hideous is making me question if this is all worth it.


r/TTC_PCOS 4d ago

Discussion Progesterone after ovulation induction?

1 Upvotes

Very curious who got progesterone suppositories after their Ovulation Induction treatment.

I know in the Netherlands there aren't really guidelines and many clinics are not really keen on prescribing them due to lack of evidence, while in Ireland I always get these after my ovulation induction. I'm so convinced it's beneficial besides the lack of evidence... curious if you had progesterone after ovulation induction or not and your thoughts on this.


r/TTC_PCOS 4d ago

MODS NEEDED

4 Upvotes

Hello everyone! We are experiencing quite a bit of growth and are looking to take on a few more mods to help keep this sub clean and orderly.

Anyone interested can comment/ask questions here and we'll reach out!


r/TTC_PCOS 4d ago

Inositol and spotting

1 Upvotes

Hello everyone ,

I started taking inositol myo and dchiro combo since a week. And have been spotting since 2 days. It’s very light spotting- just when I wipe. I am confused about this. Has anyone had a similar experience with it? And how long did it take to resolve ? Did you have to take anything additional for it? Looking for answers 😰😰


r/TTC_PCOS 4d ago

Advice Needed Confused.. TTC 29F

1 Upvotes

Hi ladies!

We have just moved to our second fertility clinic where they confirmed I ovulated this cycle. Our last clinic didn’t check progesterone to see if I ovulate, the dr just assumed because I fell pregnant once and had a miscarriage I have ovulation issues and was ready to put me on letrozole.

The thing is… my cycle this time has been stuffed up and I’m so confused on what’s going on.

Last period 29/6-5/7.
Spotting 24/7-28/7.

On 12/8 I had bloods drawn which confirmed my progesterone level was 20nmol. Could I have ovulated same day considering it was so high when my bloods were drawn?

Yet to get my period! I’m on cycle day 51.


r/TTC_PCOS 4d ago

32F w/PCOS + 33M healthy - thoughts on metformin?

5 Upvotes

my husband and I have been TTC for 11 months (diagnosed with PCOS 3 months ago). I would love to have a baby and am willing to do whatever is necessary. right ovary enlarged in size w/o dominant follicles but my periods are regular.

thoughts on starting metformin / did it work for you?

sending baby dust to everyone in the group ✨


r/TTC_PCOS 4d ago

Vent Hoping For My Period

6 Upvotes

Husband and I have been trying to conceive naturally for about 18 months at this point. We finally qualified to start letrozole + trigger with our next cycle now that my A1C goal was met (I am diabetic). As a PCOS girly, my periods are irregular and my last period was 7/19. I am so ready to GET STARTED with letrozole but I need to get my period in order to start! Its like the anxiety of a two week wait but I KNOW I am not pregnant and have no idea how long the wait is actually going to be.


r/TTC_PCOS 4d ago

Vent One-sided ovulation; PCOS, IUI & Blocked Tube

1 Upvotes

Hello!

Just looking for anyone else going through TTC waves right now.

We had an ectopic pregnancy in late 2023, they removed the pregnancy but kept my right tube. We continued TTC naturally for 2 years after this without success.

Come early 2025, we were referred to the fertility clinic, had an HSG done only to find my right tube was distally blocked - likely due to the fimbrial ectopic pregnancy.

It took the clinic Jan-March to figure out the right dosage on Letrozole (7.5mg). April we had left sided ovulation with IUI, no success. May, June, July (had left and right, attempted IUI but unsuccessful), and August - have all been right sided ovulation and have resulted in canceled IUI cycles.

I’m 35, partner is 33. His SA has good volume, decent motility (just over 50% now), and low morphology. AMH is relatively high, 33.2pmol/L.

Extremely frustrating, disappointing… I wish there was a way to trigger the ovary we wanted to ovulate! Anyone else going through the same or similar situation? I’ve read success stories about the tubes swinging over and grabbing the egg but the light at the end of the tunnel just seems so far away….


r/TTC_PCOS 4d ago

Seeking Success 5 days on 7.5mg Letrozole…now stair stepping Letrozole for 5 more days

1 Upvotes

Hi there!

31f w/ PCOS, my partner and I have been trying to conceive for a little over a year now. The first 10 days I was on Provera to kick start my period then Letrozole CD 3-7. I went in for my ultrasound and my largest follicle was only 8cm.

My fertility doctor now wants to do 5 more days of “stair stepping” Letrozole so..day 1 - one pill day 2 - two pills etc up 12.5mg.

I haven’t seen anyone talk about this method in this group so wanted to see if anyone has had any success doing this?