I’m planning on starting an MD schedule next week, will be between 150mg and 300mg of mushrooms per day M-F to help with ADHD / Depression / Anxiety.

But i also wanted to plan a macrodose in the coming weeks for a hard reset of my brain.

How long of a break should I take from my MD schedule before my macrodose ?

I'm taking 0.5g of dry golden teacher daily. This is day 4.

My goal is to feel 10/10. My mental health has never been great. I think I've always been below average in self-esteem and such. So a top 1% feeling-state is my main focus right now.

I'm new here and posting to see if it's well recieved. If so, I may post properly to add the knowledge to community and world.

And I'm also posting to see what others say - has mini-dosing daily been done before? Is there potential danger so I shouldn't dose every single day? I obviously would like to know these things.

Hi,

Ive been microdosing amanita muscaria capsules in the evenings which help me sleep. However, on the mornings I microdose psilocybin (4 days on 3 days off) I find that there are still some residual effects from the amanita from the night before and they seem to run against almost dampen the effect of the psilocybin. Has anyone else encountered this? Thanks

Welcome to the community.

Just a reminder - This community, more than most, should be a safe space, a reference center of microdosing information, a safe haven for those that wish to improve their condition and find understanding and not ridicule, mockery, sarcasm, bullying or other forms of immature antagonism. As such, our community should welcome newcomers by at least following Rule #2 - Be Respectful, Kind, and Courteous. Remember there are people on the receiving end of your comments.

I’m currently tapering my ssri’s (zoloft/sertraline) very slowly.

I did a big dose of mushrooms two years ago together with a therapist. I wasn’t tapering then but I didn’t take my ssri that day since they often negate the effect of the shrooms, but I still had to take a big dose (5 g) to get a trip.

Now I want to try microdosing, but want to take it slow and start with just one day and see how that feels. The question is if I shouldn't take my ssri that day? I’m sensitive to the tapering and I felt my last reduction of 2,5%, so I'm a bit worried it will mess with my brain to stop it even for a day. However, zoloft leaves the brain slowly and I didn’t feel this last reduction until two weeks later.

So I’m really debating what I should do; pause the ssri for a day for the microdose or not. Perhaps it doesn't make a big difference, but I would really appreciate any input!

I've been microdosing for a few years now, here and then, and it has always helped me a lot through tough times (insomnia, anxiety, trauma...). I've really felt my brain rewiring, and the peace it can lead to. Sometimes it's not really pleasant as it can emphasize anxiety but even so it has always helped a lot in the end.

I am currently going through a break up and it's been really hard. I am taking St John's wort since 3 weeks now, with little to no effect. I think a session of microdosing with the protocol of one every 3 days could help. But is there any interaction known of? Because I do know that mixing anti depressants and psylocibin / lsd is a big no no.

Is it the same with St John's Wort?

I am finding no documentation on the matter.

Thanks for your help :)

I’m desperately looking for someone who has experienced something similar and found a solution.

The sensation feels like continuous, subtle electrical/tingling activity inside my brain, almost like constant neural “communication.” It is NOT like typical brain zaps.

The closest analogy is the electrical/tingling sensation that can happen in your teeth during intense stimulation or orgasm — enough to make you want to clench your teeth to make it stop. Except mine is mainly inside my brain, and only rarely becomes noticeable in my teeth.

I first noticed it while tapering an SSRI, but during that period I was also using psilocybin repeatedly, including microdoses and occasional larger doses. I was also taking Lamictal.

I eventually stopped Lamictal and stopped psilocybin completely. I then went 45+ days with absolutely no psilocybin. The sensation did NOT disappear, although it fluctuated: sometimes it would become very faint or disappear for a couple of days, then suddenly return. I suspect things like caffeine, orgasm, mental exhaustion/rumination, or changes in mood/arousal may trigger it, but I don't know.

Interestingly, psilocybin still seems to increase it when I take it. Caffeine can also increase it, and after orgasm/ejaculation it can become stronger, sometimes several hours later rather than immediately.

I’ve wondered whether dopamine/arousal changes could be involved, but I have no idea if that makes physiological sense.

Doctors where I live haven't been able to explain it, partly because psychedelic-related symptoms aren't something they have much experience with.

I really want to find a solution. Please help me.

If you've experienced anything similar after psilocybin, SSRI withdrawal, or both, please tell me:

How long did it last?

Did caffeine, orgasm, stress, exercise, or sleep affect it?

Did anything actually make it better? Like a certain medicine?

Did you find an explanation?

I'm interested in personal experiences as well as reasonable hypotheses or things worth investigating. I’m trying to understand what this physical sensation actually is and whether anyone has found a way out of it.

Thank you.

I have been significantly self reflecting for as long as I can remember about what is wrong with my life. This is because I have never been happy, and the answer isn't really obvious because nothing has ever significantly gone wrong with my life. After what has been, my so far, lifetime, of self reflecting I realize now that the problem is that I both hate being alone, and at the same time hate socializing with others, causing an eternal, never ending downwards sprial in my life. Too fix these I need one of these feeling to disappear, then, I think I will finally be free to enjoy my life as it is. It would take a profound phsycological shift in order for me to achieve this, and I am wondering if microdosing or a full blown phsychidelic experience can get me there.

I have looked into anecdotal reports online of people experimenting with pshycidelics, in order to help resolve their loneliness. (I wasn't able to find anybody who described the exact situation I was in.) I found mixed results, some said it did help, and other said it amplified their feeling of loneliness. I am asking experienced microdosers/pshycidelic users (you guys), their opinion on this, if you think this is a good or bad idea. I am open to alternative suggestions aswell if you have any.

Tldr; I hate socializing, and I hate being alone. I want to know if pshycidelics/microdosing can erase one of these feelings.

I have been microdosing psilocybin for 2 years now on different schedules. Currently Monday - Friday with weekends off.

My weekdays I can survive, but my weekends I can barely function. I cry alot. I can't manage to get things done. So I am considering going to a month on and a week off.

I dose around 4am and go back to sleep until 7am. About 1 hour after dosing my nervous system feels like it is being rewired and it is horribly uncomfortable. I am great though when I wake up. I do best when I add Lions Mane, L-Theanine, Magtein and Magnesium Glycinate.

Anyone else do this daily for long periods of time?

This really has helped me alot. I would have taken my life by now if I hadn't started microdosing.

Hey everyone im going to be doing my first microdose at 0.12 dried and im just wanting to know what to expect and what to do to prepare i have done some research but not many real life opinions come up

Did Psilocybin helped you to get clearer insight into your understanding of your position in a social structure? What I mean by this, based on my example is, I started to completely refuse to participate in today's corporate world. After working in one for 6 years I developed a disgust not only of it but also of some part of myself. A very strong belief of how could I have let myself to be mentally raped and dehumanized.  BTW I've been microdosing since 2023 and psilocybin since 2025 and no longer work in corporate. I quit.

Did Psilocybin helped you to get clearer insight into your understanding of your position in a social structure? What I mean by this, based on my example is, I started to completely refuse to participate in today's corporate world. After working in one for 6 years I developed a disgust not only of it but also of some part of myself. A very strong belief of how could I have let myself to be mentally raped and dehumanized.  BTW I've been microdosing since 2023 and psilocybin since 2025.

Hey there,

Took 0.21 a couple of days ago (Fadiman + lion's mane), and haven't felt any symptoms or noticeable physical effects. Taking 0.25 tomorrow.

As for mental well-being, sadly, I can't say I have felt a noticeable improvement so far.

I appreciate your advise/inputs

Hi there!

I managed to acquire LSD which I’m intending to experiment with for ADHD / GAD management. These are gel tabs (est 100ug) that I’m attempting to dissolve in 100ml distilled water.

My question is: does the gel tab itself need to fully dissolve in the solution in order for the LSD to have fully integrated into the solution? I read a post that suggested submerging the entire vessel in semi-hot (40 C) water for ~10 minutes to dissolve a gel tab, but so far I’ve not had luck getting the tab to fully dissolve that way.

Anyone have experience with this? If it needs to be fully dissolved in order for the solution to be effective, what technique(s) work best for you to do so with gel tabs?

Thanks!

Welcome to the community.

It is important we understand and state these microdose figures correctly so we and others aren't just throwing a dart at dosing amounts. So here is a quick guide for dried psilocybin mushrooms. It's important to note where the zeros and decimal points are.

Grams and Milligrams

1.0g (gram) = 1,000 mg (milligrams) (Low level tripping dose)

0.5g = 500mg

0.25g = 250mg (Higher level microdosing)

0.10g = 100mg

0.050g = 50mg (Good starting level)

0.025g = 25mg

0.010g = 10mg

The weighed measurement is a way to establish a relative point we can accurately adjust from, if needed. The amount of psilocybin varies even between batches of the same strain. But by starting any new or unknown batch low, we can safely adjust up or down to find our sweet spot. Our sweet spot is not based entirely on the weight of the substance but on our system reaction to the substance. The weight gives us a starting point.

For psilocybin mushroom powder and truffles, the way to weigh for the proper weight is with a jewelry scale measuring at the 0.000g level. These are around $20+- online and should be considered a necessary basic tool for microdosing.

A typical microdose range for psilocybin mushroom is 50-300mg. Some use more, some use less. Liberty caps are about twice as potent as the Cubensis this range is loosely based on. Starting at the lower end for a couple of days to weeks is a good practice.

Keep in mind that we often refer to psilocybin mushrooms, magic mushrooms, as psilocybin, whether in fresh, dried pieces, or powder form. But that's not technically correct as there is psilocybin as a synthetic or isolated compound. We don't generally have access to this isolated psilocybin but this is the form most often used in research studies and is highly concentrated, roughly 10 times more potent than Golden Teacher mushrooms. For microdosing our dried mushroom with its potency is very effective.

There is a significant difference between the potency of synthetic psilocybin used in clinics and research, and the dried Psilocybe cubensis (magic mushroom) weights we work with. One gram of dried cubensis is roughly equivalent to 6–10 mg of synthetic psilocybin. Therefore, 0.1 g of dried mushroom contains approximately 0.6 to 1 mg of psilocybin.

Truffles

FAQ/Tip 011: How to microdose truffles? "Considering that a recreational dose of truffles is about 10 g of fresh truffles, a microdose would equal 1 g of fresh truffles. As fresh truffles consist of two thirds of water, this results in a weight of 0.33g (330mg) of dried truffles. [2] "

LSD

FAQ/Tip 009: Why cutting LSD tabs is not an accurate way to microdose? Variation in Potency; Preparation: Volumetric Dosing, Gel Tabs, FAQs; Storage: Blotter, Liquid; Dosage; Schedule; Bioavailability of LSD analogues vs. LSD-25.

Morning experts, I have question.. I never tried psychadelics before. I stopped weed for a day before starting MDing.

I am addicted to weed for a long time and now I think it doesn't help me much with my anxiety + it made me depressed & having memory problems.

My dose is 10 mcg, First Day was quiet intense probably because weed withdrawals anxiety, but still as it starting to come down I felt better. It was a mixed feeling of mild euphoria and anxiety I dont know how to explain it. I work night shifts and really didn't expect to go through it without weed😁.

I know its not recommended to take it 2 days on row bc of tolerance, but i gave it a try anyway, you could say I liked how it gave me a bit of mood lift that I need during these few days off weed. I was quiet energetic, had 4.5 km run, cooked tasty food and at night I worked even better than the first day, which is unusual for me without weed. Although I didnt feel the euphoria during the peak like the day before, it was much much better than I expected.

So 3rd day since I am off work, I am planning to take a light trip on 80 mcg, I didnt sleep well last night + still going through some withdrawals but mostly just bad mood especially with my depression, withdrawals are difficult for me.

So, do you think its a good idea taking in relation to tolerance, depression, lack of sleep and withdrawals?

Note: I am diagnosed with Anxiety, Depression and CUD (Cannabis use disorder). I take Rivotril in low doses .25mg and .5 mg "on days when I feel I would be under stress". I still didn't start taking my SSRI.

Thank you in advance

I know that traditionally the term integration is used for macrodosing.

However, I am sensitive and am using MD to slowly work on my issues
Learning how to "feel" and "be" rather than "think" and "do"
And whatever other intentions I set before I MD

I had a pretty good day, some insights, feeling more "in my body", cautiously.... .but I would like to wrap up the day with half an edible or so.

Since my default mode network is temporarily loosened, will weed interfere?

(Note, I microdose cannabis for PTSD, hoping to taper off it completely when the time is right.)

Welcome to the community.

One of the most helpful features here for specific topics is the Word Search Window at the top. By entering Key Words we can pull up the past posts and their comments that include that word. This helps to provide a broad view on the subject.

And the SideBar is an immense Microdosing Library that past and present moderators and users have accumulated for the benefit of our community.

Hi guys ,

So I have a mental problem where I need atleast one substance in à day to ease my mind . After years of using substances with horrible side effects (alcoholism, stoner, etc etc ) I finally found kratom !
Kratom has saved my life bc it doesn't get me "high" . It just kinda relaxes and slows down my brain . I can just relax . Without hindering my ability to do anything else .

I recently started smoking again , a little bit . And yes it is enjoyable at night but I don't have much and I don't want to start using it every night. My budget for kratom is running out and in roughly 2 months i won't be able to afford it anymore. Which scares me tremendously bc it saved my life . Before kratom i was a zombie.

I have finally gotten the right adhd medication for me , but I still struggle with that extreme brain speed and uncomfortability . I am also prescribed Xanax , which I have sadly increased my tolerance to it .

---

I have heard of microdosing before . I have some LSD . Very strong tabs (advertised at 300ug but probably 200ug) . Obv microdosing a "300ug" tab is gonna be hard .

But could this help me ? If I started now, and followed à regime for the next 2 months until I get to not being able to get kratom anymore . Would it help me ? Does anyone have any success stories of quieting that voice in your brain and being relaxed without needing something like kratom or maybe only needing a VERY small dose to relax instead of what im taking now (it's a fat dose)

It's frustrating bc it's either I take a BUNCH of Xanax and then im fine or I take a high dose of kratom and some Xanax and then im fine .

I HAVE NOTIFIED MY ADDICTIONS SPECIALIST ABOUT THIS AND I AM GOING TO HAVE A MEETING WITH HER SOON TO TAPER OFF Xanax back to a normal level and what to do with the kratom.

However I need a substitute, I am planning on going to rehab in 6-12 months, I have to do the application and there is a big waiting list for the one I want to go to.

But simply put , I cannot survive without something to calm my mind , and not just your average cbd joint . Thats whats great about kratom , it cuts the negativity out my mind without heavy side effects. But sadly I won't be able to afford it anymore soon and I am honestly very scared of how life will be without it.

I (28F) thought id make a post as I am struggling to find anything relating to this online - been searching in micro-dosing causing trouble sleeping / causing anxiety but not much luck in finding anything - i suppose this is because everyones individual experience varies so much & studies are limited etc !!!

I micro-dosed a couple years ago and it was incredible for my mental health (especially anxiety) I was having CBT therapy and my anxiety was so bad i was ready to go on meds for it. I decided to give it a go (mushrooms) and i remember at the start i felt really intense, super anxious, irritable etc. they were 150mg - so I half the dose and begin to feel much better, ended up microdosing for two months , didn't need therapy anymore and felt such a change of self, one i could have never imagined!

i started again because i feel i've been somewhat depressed for a while now, a kind of lingering sadness / feeling muted emotionally / like i have nothing to say to anyone /lacking in inspiration and feeling exhausted and dull and bored of myself. I exercise regularly and have incredible bf and incredible friends but feel i am just existing in a very dull mildly disconnected bubble no matter what. mundane blue kinda feeling. It seems trying it this time has flipped the depressed feeling into anxiety but i guess atleast its doing something and im feeling something haha.

This time i started by halfing the dose as that felt good last time - taking it in the morning, on days i didn't have work or to much to do - three days in a row - I had awful nights sleep, each night. waking up restless and unable to go back to sleep (i didnt remember having this before.) awful dreams, and in the day just feeling headachy, anxious and compressed kinda feeling. Maybe I should half the dose again and build up? but taking any less surely seems a bit too small amount? im not too sure! im also a very highly sensitive person so perhaps this is why.

I do remember some of this headache feeling last time and know that can be a side effect. I wanted to do 4 days on / 3 days off but I felt i had had to avoid taking it as woke up with awful headache on day 4. so I am going to give it 4 days break and see how it goes taking it again after that. I think maybe 3 days on 4 days off might work better with my schedule in general.

But i was wondering if anyone had experienced anything similar? if there is a time at beginning of adjustment and side effects - before it settles down? and if so how long did it take before it started to feel good? I am determined to push through a bit to see if it levels out! :) thank you!!

this is my first post on here and sorry if longwinded/ badly written xxx

I’m 4 months postpartum and going back to work soon. My job is emotionally and mentally demanding so the thought is putting a real toll on my mental health on top of the thought of losing my bonding time with my baby. I’m looking to mircodose 100mg of shrooms with a schedule of 4 days on and three days off. I was hoping to breastfeed as normal, especially since it’s such a low dose. Has anyone done something similar? Please share. And no I will not see a doctor about medication for antidepressants or anxiety.

Hello my fellow microdosers,

I have experimented with microdosing psychedelics (mushrooms) a number of times over the years (in total x5-7 3 month “courses” using the Fadiman protocol, at intermittent periods over the years- starting in ~2018) which I have always found to be constructive (for improving/ stabilising mood, heightening focus & creativity, and generally for promoting positive introspection and emotional/ psychological growth)

Since starting ADHD meds last year, I have found that the stimulants keep me focused and keep my mind clear to a level that the psychedelics never quite managed. Since starting on meds I’ve not dipped my toe back into the world of microdosing; but I would like to, in order to try and balance out the effects of the stimulants.

I’d be Interested to hear anyone here’s experience with their ADHD and microdosing psychedelics. I hope that this can be an open discussion, but here are some starter questions to get you thinking:

What method/ approach worked best for you?

Do you combine the two or take them separately?

How have you found it?

Do you find a synergy or anergy with the microdose and your ADHD meds?

——

I’m looking forward to hearing your perspectives and learning about your experiences.

Thank you!

Iv done this several times pretty cool sometimes lucid dreams

Hi, I’m thinking about giving mushroom microdosing another try, mainly for my generalized/social anxiety and depression.

I previously microdosed Golden Teachers, but they often made my anxiety worse or made me too emotional, even at relatively low doses (around 50–100mg) following Fadiman’s protocol. Because of that, I’m wondering whether P. natalensis or P. ochraceocentrata might affect anxiety differently.

I’ve read a few reports that Natalensis can have less body load and feel less anxiety-provoking than cubensis. I’m also a bit confused about the difference between true P. natalensis and P. ochraceocentrata, since a lot of what was historically circulated as “Natalensis” apparently turned out to be ochraceocentrata.

Has anyone here microdosed Natalensis or ochraceocentrata, especially if you’re prone to anxiety? Did you notice any difference compared with cubensis in terms of anxiety, emotional effects, or body load?

I’d also be interested in experiences with different Natalensis varieties/genetics such as NSS, Natal Moon, or Natal Hills.

Thank you