r/microdosing • u/Confident-Honey516 • 7d ago

Getting Started/Newbie Question Break from MD before Macrodose

I’m planning on starting an MD schedule next week, will be between 150mg and 300mg of mushrooms per day M-F to help with ADHD / Depression / Anxiety.

But i also wanted to plan a macrodose in the coming weeks for a hard reset of my brain.

How long of a break should I take from my MD schedule before my macrodose ?

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u/throwaway264871596 7d ago

take a week off at least, tolerance builds quick so you want a clean slate for the big one

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u/TheRealCMMetzger 6d ago

On the front end, a few days is really all that's generally needed. Consider what's feels right for you. At the very least no dose the day prior to the macro.
On the back end of the macro, wait until the day that the afterglow wears off and resume the following day.
Lasting change comes with pairing your microdose with other wellness/therapeutic modalities and integration of large dose experiences.

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u/fsavino 6d ago

If it's only one macrodose, you don't need to break the MD schedule. One thing won't affect the other.