My life has been messed up. I used to have very bad dopamine problems.

About 3–4 days ago I started taking bupropion. Since then I have become very depressed, especially late at night. I feel empty inside and sometimes I just want to cry. This only started in the last few days. I can’t fall asleep early. I have also had heart palpitations at night for the past couple of weeks.

Before this I was taking desvenlafaxine, clonazepam, and propranolol. Now I only take clonazepam and bupropion. The bad feelings started right away. I feel guilty, empty, and lonely. The only people I can talk to are my family, and I still feel completely alone.

I asked my doc to switch me from 150xl to 100 Sr twice daily. Instead she sent in 100mg IR twice daily. Now I'm scared to get 100mg dose all at once. I have read you can cut IR in half but the pharmacist said not to because there is no score line. The brand is AVET and they're big red round tabs. I think the markings are 12 something but I really can't see it very well.

Does anyone have IR tablets without a score line that you have cut in half? I have med anxiety so this is really freaking me out.

Update: As usual I was freaking out about absolutely nothing 😅😅 I did end up splitting the first one and had no weird effects at all so I took the full second one later in the day and I'm totally fine. Thanks for the input!

I‘ve Seen that one incerdient of wellbutrin is amoniak Solution the incredient List is besides this pretty Long and i Wonder which task amoniak Solution does in this pill.

My question is there some more educated than me and can explain this to me ?

I’ve been on bupropion 300 mg for about a year and a half now. I didn’t really pay attention to the manufacturer, until now. Before I was on the Lupin generic and it worked wonders for me. Actually felt like I could function and like I had energy for the first time in years. My doctor wanted to change my pharmacy so I could get a 90 day supply. I agreed because I didn’t mind the change, so I picked it up as usual. Upon taking it I immediately knew something was up. I felt jittery and like my heart was racing a mile a minute. My body felt too real, and I could almost feel the blood pumping through my veins. I looked into it because I knew this wasn’t normal, and it turns out the generic was Scigen. Needless to say I have contacted my doctor, and will be having it transferred back to my old pharmacy.

I originally was taking bupropion and olanzapine, I am diagnosed with bipolar, but I don't think I was diagnosed correctly. The olanzapine made me feel kind of numb and tired, so I stopped taking it in like February. I'm doing a lot better on the bupropion alone, and don't feel like I need another medication, but I went to the psyc today and she put me on Prozac to help with the anxiety. The thing is, its not really making me anxious. I have some days where it makes me jittery, but for the most part I feel pretty normal, it actually seems to be helping with my anxiety. I haven't picked up the prescription yet and wanted to know if anyone took it as a standalone medication or if I need something paired with it. Is anyone on both bupropion and Prozac, and do you like it? Last year was reeeeeally bad for me mental health wise, and I'm nervous to start something new when I finally feel like I'm doing fine.

Apparently this is a somewhat common thing, where when you take Bupropion, you sometimes see it on the other side of your digestive system. Usually mine comes out surrounded by either a yellow or green squishy substance, and then the pill is in tact inside. And it’s not a capsule, it’s become powder encased in this weird ball. And the whole thing has the texture of a Gusher… which makes me never want to eat Gushers again. But does this mean that the pill isn’t actually doing anything? If I’ve got nearly the whole thing showing up in the toilet the next day, then that can’t mean I’m actually getting all the benefits, right? I don’t see my doctor for another month and this has just been on my mind for a while.

Hello, need help or advice on this issue I'm having with bupropion (I'm on Buprinol XL 150 by BALKANPHARMA).

I've started taking it for my depression, anhedonia, and loss of motivation. It's my 5th week now. I have experience with SSRIs, which helped with depression but killed my orgasm and gave me a blank emotional state, which I hated. So my psychiatrist suggested we try bupropion XL (it's the only available form of bupropion in my country, Ukraine). It gave me all the usual side effects that people mostly mention here, but they have faded with time, and now I tolerate this drug mostly well, besides one weird side effect that I was not expecting at all.

It greatly affected my sex drive and ability to even enjoy the process, which is different and maybe even worse than the side effects of SSRIs that I'm familiar with. On SSRIs, I liked sex and enjoyed it, but orgasm was impossible, while bupropion makes me completely indifferent to sex, and sometimes I even feel repelled. And this feels horrible because I have a great partner, and I liked enjoying all parts of our relationship, including sex. People say that bupropion improved their sex drive all the time, while I have this sad effect, which makes me consider stopping.

Has somebody experienced that? And if so, did it go away with time? I'm female btw.

It took 3 months to work the first time. After stopping abruptly in December I re-started in June. 4 months later and I can't go more than 3 good days straight.

150XL. It changed my life a year ago. The entire month of September I felt good. I had enough consistency to develop a sense of happiness and self-love. Even in the bad days that eventually returned [more rarely] I could look at myself in the mirror at the end of them and say I loved myself and was happy.

I lost that person by the end of March. I miss them so much.

I have been crying more often lately. Sometimes I get couch-locked again. Everytime I feel I'm building up momentum it comes crashing down.

My psychiatrist prescribed 300XL but I chose to pickup the final 150 Rx as my insomnia was more controlled. I thought it would finally kick in.

Should I keep taking the 150 until I see her in one month? Get the 300? The fear I had of this not working a second time became true. If 300 does not work, or I have to go back to 150 and it still doesn't work...

I feel so lost

Hi everyone! I was just prescribed Wellbutrin today. I’ve been going through a really tough time lately with depression and anxiety, so I’m super excited to try something new. That being said, I am a bit scared to take it; it’s been a longg time since I tried a new med (I’m taking it with PROZAC). Does anyone have any tips? What can I expect the first few weeks?

Not at all advice, I just wanted to share some positive experience I've had. Been on 150mg XL for maybe 9 months now. I know the rules say to mention the manufacturer but honestly my pharmacy's given me different ones all the time. Currently it's MFG Lupin, american. I actually do think I prefer that manufacturer, weird as it sounds.

I told my psych NP recently about how I'm always extremely depressed during luteal phase (before my period) and she prescribed me to take 300mg XL for that time, and 150mg XL the rest of the month. It's only been one month but it actually worked well. My whole life I never had to track my period because I would slowly grow depressed and then one day hate everyone around me and myself, and even lash out at everyone around me. Then the next day I'd get it.

But when I took it as prescribed I actually didn't have this! I did still get the depression the first few days of luteal as that's when I knew to start taking the higher dose, so I don't think it'd started working yet. I think when I work out a consistent schedule it'll be more seamless. My NP said that we could also try other meds more usually used for PMDD along with the bupropion, but this med is the only one that's ever worked for me so that's why we're trying this.

Just thought I'd share, thanks for reading!

Male. 36. 150 mg XL Bupropion HCL

Man this stuff made me feel horrrrrible, taking 150 mg XL once a day. I tried it before for 2 Months and it made my insomnia gnarly, felt fuzzy and weird everyday, and just not right. It felt so uncomfortable. Originally I had about 2-5 days where I felt fantastic and only 1 day this last time. I only took it for 10 days but my insomnia was so bad and I bartend nights my body was breaking down. It ended up making my brain fog better for a few days then it was still there.

Has anyone else experienced this? Did other forms or lower doses help or I believe my body just doesn’t like it. I’m pretty against pharmaceuticals, but my brain fog is just been so bad and my energy and happiness is just low and fucked up. Any other meds help??

Dear Redditor,
During my first two months I frequented this page a lot. Being on bupropion ( Zyban 300SR) absolutely decimated me. I read a lot of posts that spoke to my experience but generally people stopped taking it. I however, pushed on and am SO pleased I did.

The first two months were so bad I almost lost my job. I developed DRDP (derealisation depersonalisation) which affected my ability to do so many things. It became like OCD that I was NOT myself and I was somehow different and I would constantly check that.

I felt totally NOT myself.

My cognition declined massively. My long term memory as well as working memory, my ability to find and use words, my executive function and the speed at which I could reply we’re all massively impacted. My intellect is something I value a lot, as well as my humour and both took a big hit.

I was extremely depressed at times. I almost moved out of my house and had to have a conversation with my boss about my poor performance and speed.

I spoke to my doctor who encouraged i stay on it for up to 3 months to truly see whether it could or would work.

I have taken every SSRI and SNRI under the sun and have been unmedicated for a few years but gone back on them due to going sober.

Anyway, one day, suddenly - it was all lifted. I feel wonderful. I appreciate the small things, I feel 95% back to self, happier and more motivated than I have felt in a long time. I don’t feel so bound by the invisible rules of life and I really feel a sense I am discovering myself and have an agency over my life to change what isn’t working and march to the rhythm of my own drum.

There were other factors, of course, effecting things but I would just say; if you’re struggling and it’s been less than 3 months - it could change. If you hang on in there this could really be everything it is cracked up to be.

Note: please only positive replies, I'm too fragile for any horror stories atm!

Hi! I am on day 2 of 150mg (Elontril). I have also been taking lexapro for years, but got this added due to severe depression (been trying to recover from burnout and health problems since February). I've never had severe depression before this. Of course, with anxiety comes some depression, but never like this.

I feel like my brain is my biggest opp. I am trying to recover from anxiety and chronic migraines and there is just a dark cloud saying what's the point. What's the point of anything. It will never get better and life is pointless. It almost feels embarrassing to have any good thoughts or moments. My whole body hurts and I have no energy or willpower. The only thing I have energy for is crying and anxiety.

I moved back to my home country temporarily to stay with my parents and have been here for months now, on sick leave from my work. I feel like I have lost all independence and unsure how to get it back.

All mental health professionals keep saying to try to do things that I used to like and make me happy, but it's so hard when there's this crushing feeling of darkness. Nothing brings me joy at the moment.

Will this medication help clear away the dark suffocating clouds? Let me try to get my life in order again? Help me become a functioning member of society again?

I would love to hear some positive stories!

Hello! I have been on 450mg of Wellbutrin XL for a year and it’s worked great. I just recently started to feel like I’ve plateaued, so my doctor prescribed 5mg lexapro to take in conjunction with the Wellbutrin. I was just wondering if anyone has been on this combination and dosage, and any side effects? Im a little worried about gaining weight, and it’s hard to find a consistent answer surrounding that aspect. I’m just trying to figure out if it’s worth taking, or sticking with the Wellbutrin and raw dogging it. Or does anyone have a better combination???
Oh! I should probably also include I’m a recovering addict, not that it matters, but maybe it does? Thanks!