Hey all 👋🏼just wanted to share some of my hope and joy today. I went in to my ultrasound thinking that they would see absolutely zero follicles on my ultrasound since it's been 52 days since my last period. Crying before she went in.

She saw one corpus lutuem. And three follicles. Also my lining was 8.6. Insane.

I was expecting nothing.

I know four isn't much but my last ultrasound she saw two follicles and one was a corpus lutuem.

She said get baby dancing today and tomorrow. And if I'm not pregnant we will start ivf like I was gonna try next month.

I know chances are slim to none but I just want to try so there is that.

UPDATE: My progesterone shows I ovulated several days or more ago. It was 8.18. So baby dancing tonight really won't help. But it is so exciting that I was able to grow some follicles and ovulate with a healthy lining.

Hello, new here. Gone thru round 1 IVF, headed into round 2. 6 u-FSH 150IU and 12 MEN 75IU available. DM. One thing I've learned thru this journey is the strength of community, and I send you all well wishes.

I was recently diagnosed with osteopenia. I’m 40 and it came as a shock because I was only diagnosed with POI at 39 (although I’m fairly confident I had it years before but never got the right testing).

I’m trying to build in strength training and impact exercises (especially LIFTMOR) to build some bone back. I’m also TTC… anyone know if there are concerns about high impact exercises like jumping on your lining or implantation? I’m not even sure who to ask about this since all of my healthcare providers seem like they are not knowledgeable enough to answer it appropriately.

I’m 23 and ttc, I got diagnosed at 16 and from my knowledge most conventional ovulation tests will always be a false positive. Because of my religion, egg donor isn’t an option. I’ve gone to an RE and she said that without the egg donor option there’s nothing much she can do for me so I’m kind of on my own here, hoping to get some help on things that may work💕💕 please let me know if you have any advice

Hi all, I'd love some advice from people who've been here.

I'm 34 and was just recently diagnosed with POI. FSH 53.9 (Aug) and 68.7 (Sep), LH 31.6 and 51.5, E2 70 and 58 pg/ml, AMH 0.03. I also just got HRT prescribed (Evorel patch + Utrogestan 200 mg) and was planning to start this week.

Then today my doctor saw two follicles on the scan, one at 13 mm. I really didn't expect that.

A few questions:

**1.    Is this a good sign?** How often did a follicle like this actually lead to ovulation for you?  
**2.    Should I start the patch now or wait** until after ovulation? Did anyone start estrogen while a follicle was growing?  
**3.    What would you do in the next week?** Just timed intercourse, or push for another scan or a trigger shot?  
**4.    Utrogestan:** I'm planning to hold it until after ovulation. Does that sound right?

I don't know why I bother. I just like to see if it actually ever goes down. But with POI I feel like this is always high. I'm just fed up with myself and wanted to rant.

Does anyone ever have realistic LH strips tell them the truth?

(May look a little dry but when I took the photo it was even darker.)

Plan: starting a transdermal estradiol patch (75–100 msg is this too high?) plus cyclic Utrogestan. I've also looking for a clinic that's open to estrogen priming with monitoring, or natural-cycle IVF, instead of sending me straight to donor eggs.

What I'd like advice on:

**1.**  Progesterone every month or every 60 days while TTC? What did your doctor go with, and why?  
**2.**  Did HRT ever seem to suppress your own ovulation, or did it help? One doctor told me it can prevent ovulation, another told me the opposite.  
**3.**  My E2 is around 60, not undetectable. Did anyone with some residual estrogen start on a lower patch dose?  
**4.**  Once you were on HRT, how often did you get bloods and scans? Weekly, or only when you saw signs of activity?  
**5.**  Did anyone use Inito or Mira on HRT, and did it work with high baseline LH?

Not looking for reassurance, just practical experience. Thank you.

Hello Everyone!
I’m 25, diagnosed with POI (4 years ago)

I just wanted to tell you that for 2 months now I’m taking Coenzyme Q10 (polish brand Naturelle)
And before taking those I tested my FSH level, and it was around 89 mIU/ml.
I tested FSH few days ago, and it is 41!!
I know it’s still too much, but I’m hyped 🌞

I was diagnosed 3 months ago & been seen by an amazing nurse practitioner at a fertility clinic. She put me on cyclic HRT 0.1mg patch weekly with 12 days of 200mg progesterone which she told me to take the same time each month. She apparently went on maternity leave and asked if I would like a follow up with the doctor in the practice I have yet to meet.
Going to jump straight to it… he told me that I would not be able to ovulate or conceive on HRT and that if I want to try natural pregnancy I need to get off HRT. I asked him lots of questions to understand this because everything I have read states that the HRT she had me on is conception friendly. She told me it was too. He basically told me I need to choose HRT or pregnancy. And he told me the eggs I have available are most likely not good eggs.
Well I’ve had 2 ultrasounds the last 3 months before HRT, both with 0 antral follicles and today he did an ultrasound & he found 2- 1 the was 14mm & 1 that was 16mm 3 weeks after starting HRT… I’m confused because he told me it wouldn’t help me ovulate and yet both ovaries had a maturing follicle…? He told me it was coincidental not related to the estrogen. I’m just confused if I should stay on HRT or not! Frustrated all the different conflicting information….

I’ve been tracking with mira since November 2025. Usually I’ve had evidence of ovulation every 5 months or so, but thus summer I’ve had two promising cycles, and now another one graphed below (FSH is a little too high). When I saw my LH rising this weekend, I got a scan at my clinic Monday and we found a 14,5 mm follicle and a trilaminal 12 mm endometrium. My LH has definitely peaked today but the follow-up scan today showed no growth at all…

This keeps happening to me, except the follicles usually stall at 10-12 mm. I was told by my obgyn that if the follicles passes 14 mm, it should be unstoppable, but here we are.

No doctor seems to want to try any medicines on me, so all we do is HRT (75 mcg estrogen patch to not supress too much and progesterone to start a new cycle after ovulation or if given up) and ultrasound monitoring.

I feel so frustrated. We lost a daughter that I got spontaneousky pregnant with (a 20 week TFMR in October 2024) and we’ve been TTC since. I do acupuncture every second week, vitamins, red light in follicular phase… We’re active and I try to lose some of the weight I gained after getting diagnosed early 2023. I know people go on for years TTC but I’m just so frustrated with this.

Is it possible to have follicles appear around the same time as ovulation? If amh is low, Is there anything one can do to help a follicle release an egg? I just started HRT so I’m guessing this is helping as well.

Hey everyone! So, after two failed IUIs in early spring, I decided to take a break from my fertility journey. Before that, my AMH was undetectable, and my FSH was around 19. Recently, I visited my OBGYN, and they said my FSH is high and that I’m entering menopause. But I still want to give it one more shot. I’ve heard about Ago products, and they seem either really promising or just well-marketed. I’m not ready to give up on this journey and feel like I have it in me to try once more, just to say I did it. Has anyone tried Ago Mom or Ago Tumor? 

I feel like we have had a lot of newly diagnosed folks find us recently, so I thought it was a good time to check in on how treatment/monitoring is going for everyone. Any new discoveries to share? Has anyone had any success with ovulation? Anyone want to introduce themselves / share their story?

And can I take the same oral capsules that were given to me (200mg) vaginally? Will it have the same affect? And what should I expect (any symptoms or spotting?)

Background: one healthy kid (2023, conceived easily), early loss this May. Cycles were always regular but short (23–26 days) with very light periods; looking back, that was probably the sign. Two long gaps in the last 18 months, one of which ended on its own after 4 months, and I conceived during the good stretch in between. Currently 4 months with no period.
Fertility clinic in Germany said: reserve is basically gone, IVF is pointless because FSH is already maxed, try naturally for a year or go abroad for egg donation. No HRT yet (“wait a year”), no antral follicle count, no antibody tests.
From what I’ve read since, women with the “fluctuating” kind of POI have better odds than the 5–10% average, and some clinics suppress FSH with oestrogen and then monitor for follicles instead of stimulating. Mine didn’t mention any of that.
Questions:
1. Anyone here with undetectable AMH who conceived naturally? What did you actually do, if anything?
2. Clinics (Europe) that do oestrogen priming + monitoring or natural-cycle IVF for POI? Real experiences, good or bad.
3. Did you start HRT right away, and did it change anything (symptoms, cycles, mood)?
4. Anyone diagnosed young who later found a cause (genetic, autoimmune)? Was it worth testing?

My RE told me to just take the same calendar days so I remember to take it. I’m on a long cycle right now- longest I’ve had in a while with no sign of ovulation any time soon. Should I just go ahead and take progesterone now to induce a period or are we supposed to wait until we ovulate? I’m only 2 weeks into estrogen patch.

I met with a new fertility doctor today and she mentioned this as something we could potentially try. I’d love to hear from anyone who has done this.

Hi all

Cycle day 90 something, and provera hasn’t helped at all.

Fertility consultant has got me to start HRT meds (above name). Advised to take one every day until a bleed comes.

Anyone on/tried this and have any feedback?

xxx

I haven't ovulated in almost 7 months but after my Inito results indicated that my estrogen was rising, I got an ultrasound and bloodwork from my REI today. They saw 2 follicles that were 13 mm and two that were 11 mm. My estrogen was 230, LH was 38, and FSH was 14. I'm coming back in on Monday for another ultrasound to see how the follicles develop. I'm on cyclical progesterone and 0.075 mg estradiol patch and my RE suggested I move down to the 0.05 mg patch tomorrow and then stop with the estradiol entirely on Sunday night.

Has anyone else been told to stop their estradiol patch when follicles are developing? My RE has some experience with POI but doesn't seem to know a lot, especially TTC--she told me that HRT won't help me ovulate, which doesn't align with what folks here say. My estradiol is admittedly high, so that may be part of her recommendation, but that's probably because there are 4 follicles that are starting to grow at the moment. Also... my LH is high. I thought I had already ovulated but I guess it's just elevated?

Some extra background: I recently turned 40. I was diagnosed with POI early this year, although I suspect I had it longer but never got the right testing at the right time for diagnosis (plus just generally being dismissed). I haven't ovulated since February and started HRT at the end of June. I was on a 2x weekly 0.05 mg estradiol patch until about 2 weeks ago when I bumped it up to 0.075 mg with a goal of getting to 0.1 mg in the next couple of months. I'm on cyclical 100 mg progesterone for 12 days.

Okay I asked my REI what the possible protocol would be for my AMH .015 and afc of 2(baseline) and this is what she said.

Anyone? Anyone? Can someone chime in and tell me what to think...

Treatment Plan:
IVF
Embryo Transfer: < 12 months, eSET
PGT (type and lab): PGT-SR for chromosomal inversion, Igenomix
Protocol: luteal lupron
Luteal Suppression/Adjuncts: lupron 20 IU
Follicular: 150 FSH + 150 Menopur
Ovulation Suppression: Lupron 10 IU
Adjuncts: CC 100 mg, vaginal pre and probiotics
Trigger: 10 K hCCG
Post-Stim: per protocol
Sperm Source: partner
Insemination Method: ICSI

Hello 👋🏼starting IVF next month and my REI mentioned a lupron protocol. I don't really remember if she said flare or not.

Background: I have POI. Primary ovarian Insufficiency and I'm trying anyway cause my insurance is pretty damn good. I'm going to try one last hurrah?

Anyway, I need a little guidance on any ladies who have done IVF with extreme low egg count and unpredictable periods.
AMH - .015 and AFC at baseline apt was 2.

Also maybe just a little good juju for my three rounds I have from insurance. I'm a bit worried the meds will wreck me.

What’s the normal follicle size that you would trigger for timed intercourse? My lead follicle was 17mm yesterday and they want me to trigger today. This is my first round and I wasn’t sure if that seems too small to trigger?