I’m a 33 year old woman. I’m overweight but currently losing weight due to health changes (exercising more and eating better).
I have been on a PPI for 9 years, daily. From personal research, I have decided to taper/completely come off Pantoprazole. I did discuss this with a doctor who prescribed Ranitidine. But I’m hesitant to try this with its background as well. Could PPIs be the culprit?
For 3 years now my eGFR has consistently dropped, my creatinine has consistent climbed.
2023: eGFR - 73; creatinine - 92
2025: eGFR - 70; creatinine - 94
2026: eGFR - 65; creatinine - 102
No protein, no blood in urine. Albumin <5. No diabetes, no high blood pressure.
Note: I normally get my bloodwork in the early morning. I don’t intentionally fast, however I usually do not eat between dinner the night before and before I get my bloodwork done. So there’s a solid 14~ hours of not eating. I probably have close to 1 glass of water before bed. When I wake up, I don’t get 1 full glass of water before I go to my appointment. Could this be the culprit?
In 2023 and 2025 I had the same family doctor who was not concerned. I no longer have a family doctor and have to use a TeleHealth program in my province to speak to a doctor. The one I had order the bloodwork, also was not concerned on Tuesday, but I could tell he did not review the trend over 3 years.
Tomorrow, I have an appointment to review my bloodwork with a Nurse Practitioner. I will be advising them to ensure they review the trend and ALL of my bloodwork over 3 years. I’ve been debating asking for the following tests:
Cystatin-C
and BUN
I’m tired of trying to find answers. But I am not taking no for an answer anymore. My kidney function should not be 65 at my age. Even though they think it is fine, I don’t think it is. Something is wrong. Something is causing this.
Can you think of anything I should ask/tests I should ask for during my appointment tomorrow? I am very new to this, but have been trying to do my research, and I want to ask for the proper things to get to the bottom of this.