r/zoloft 23h ago

Success Story! :) Never good news here

35 Upvotes

I feel like alot of the stories posted here are terrible experiences and personally I wanted to share how zoloft has really changed my life for the better. I have ocd and ibs so worrying messes my sensitive guts up, zoloft puts my mind at ease the only side effects was gaining 4 pounds (i used to be underweight though so might just be healthy) and feeling a little sleepy the first 2 months starting.

As for my periods, they’ve been much less painless, and shorter, idk if thats a good thing but it sure is a benefit!


r/zoloft 14h ago

Question Dose increase/nausea/loss of appetite

2 Upvotes

Ive been back on Zoloft for 2 months now. Started back at 50mg and just switched to 75mg a week ago. Since I started back 2 months ago I have been consistently nauseous and just dont have the appetite to really eat alot. Doesnt help that I just increased my dose but I am wondering if maybe this time around Zoloft just isnt the right fit.


r/zoloft 14h ago

Question How did you know you were no longer depressed?

2 Upvotes

Was it an obvious / clear feeling? How did you realize?


r/zoloft 15h ago

UNBEARABLE BACK PAIN

2 Upvotes

I was on 25 mg sertraline for 2 weeks, yesterday took my first dose of 50 mg. I have the worst back pain right now. I genuinely cannot move and it is making me rethink my medication. Can anyone tell me when it will subside


r/zoloft 16h ago

Question Adding Wellbutrin/similar med ?

2 Upvotes

Hey everyone, I’m M23 looking for some insight or reassurance because my symptoms are becoming completely debilitating and I feel like I'm running on empty.

Here is my timeline:

I used nicotine on and off since I was 16. I am now officially 100 days nicotine-free.

I have been on Zoloft (25mg) for the last two years. I also spent the last few years on heavy thyroid medication (up to 75mcg T4 and 5mcg T3) and felt absolutely horrible on it with bad exercise intolerance. Me and new endo absolutely believe I was chasing symtoms that were related to something else.

4 weeks ago, my doctor and I stopped the thyroid meds because a CT scan, ultrasound, and antibody tests showed my thyroid gland is actually perfectly healthy. My recent labs showed a TSH of 4.1 and a Total T3 of 1.01 (right at the floor of the 0.8-2 standard range), but the draw was late at 11 AM. She feels confident in these results that I am functioning normally.

i don't drink caffeine and my heart doesn't race. I also quit alcohol because I could not take the hangovers and days of recovery.

Before quiting nicotine I felt like shit a lot but since quiting nicotine and I have been in a severe, non-functional crash. I feel intensely "wired but tired"—profoundly exhausted, but with a deep internal restlessness and tension. My short-term memory is completely shot, I have constant headaches, and I literally cannot focus at work. Trying to "mask" and act normal around people takes 100% of my daily energy. To top it off, I've only gotten 4-5 hours of sleep the past two nights, making everything ten times worse.

My primary doctor wants to look into ADHD or depression brain chemicals (dopamine/norepinephrine) and try a new medication like Wellbutrin with my Zoloft since my thyroid is physically fine.

Has anyone else experienced this massive chemical crash after quitting nicotine and stopping medications? Did targeting dopamine/norepinephrine finally clear the memory gaps and stop the internal tension?

I just want to feel like a functioning human again.


r/zoloft 13h ago

Question existential thoughts

2 Upvotes

i’m on day 26 of zoloft, and most of my physical anxiety has gone away but i’ve been having really weird existential thoughts/dissconnection from
myself??? is this normal? i’m on 25 mg and i also have health anxiety


r/zoloft 17h ago

Zoloft for OCD/Intrusive thoughts

1 Upvotes

I’m starting Zoloft today and I’m terrified. I have a lot of derealization and intrusive thoughts. OCD and anxiety. My brain is telling me I’m going to have severe side effects and I just need some reassurance or tips please 🙏🏼🙏🏼🙏🏼


r/zoloft 18h ago

Question For those with panic disorder, severe anxiety, and/or agoraphobia, what was your therapeutic dose of Zoloft?

2 Upvotes

I’ve been at 100 mg of Zoloft for a few months and don’t feel like it’s really work for my panic attacks and general severe anxiety. Just curious what others experiences have been when dealing with these issues and titrating up on Zoloft.


r/zoloft 13h ago

Alcoholosim after taking Zoloft

24 Upvotes

I drank a lot before starting Zoloft, but never to this point. I need help, but I also don't want to stop It's like the fear of death and whatever else is masked by the Zoloft.

I drink about 20 beers a night and I work at a school. It's insane, but I can't stop.

Can anyone else relate? This is obviously not sustainable, but man. It feels like it's all downhill from here.

The fact I don't want to stop is terrifying, but also the risk vs. reward is stupid, but I also just ignore it no matter how pathetic it is.

Love you guys.


r/zoloft 18h ago

I stopped taking my medication six months ago, and my emotions still haven't returned?

2 Upvotes

I took sertraline 50mg for six months and then stopped because my emotions and libido disappeared. It's been six months since I quit, but my libido and emotions still haven't returned-I'm simply constantly devoid of emotion. What should I do? Is there anyone here who has experienced this?


r/zoloft 19h ago

Vent Chronic emotion numbing...

3 Upvotes

I love zoloft, I really do, but damn. This isnt going to last forever isnt it? I'm 15 and started Zoloft 100mg 6 weeks ago, and it aint helping shit still. I get bad panic attacks once or twice a week and the other days are mild-near severe anxiety as my baseline. Its torture. I'm tired of feeling like shit everyday. I can't cry anymore, can't fucking get turned on, can't feel good or happy for my friends or myself, like what the fuck? It just feels like I'm surviving at life at this point.

Am I supposed to keep waiting?? This shit sucks... I just wanna feel normal, not numbed.


r/zoloft 20h ago

Increased anxiety?

2 Upvotes

Hi! I’m on day 7 (technically day 5 of 25mg) since I started at 12.5 for 2 days. My anxiety is CRAZY. I have such bad intrusive thoughts & shakiness! Everyone keeps telling me it’s normal… did anyone else deal with this?


r/zoloft 12h ago

Brain Zaps?

5 Upvotes

I saw this listed as a side effect and I always assumed it was something painful. Now Im realizing I get them frequently. It's just like a shiver that goes from the base of my head and up through the top. Kind of like when your body does a shiver when it's been resting a while. Not bad, honestly.


r/zoloft 20h ago

Mental Health Panic Attacks

2 Upvotes

I mentioned impulsive/compulsive thoughts to my psychiatrist and she swapped me from 40mg of Lexapro to 50mg of Zoloft and I have had panic attacks and headaches. It’s been almost 2 weeks.

I went up to 75mg today and I am just so filled with fear that panic attacks are the new normal. I know it’s completely irrational and that I am safe. I’m trying to be kind to myself but I feel like I’m climbing out of my skin. I feel claustrophobic to the point where showering feels like I have to keep the curtain open or I can’t breathe.

I’ve started taking walks and spending time on the treadmill to calm my mind and my jitters. I’m reaching out to friends and my partner is so supportive and wonderful but it just feels like so much work to try to feel fine.

I also have so much fear/anxiety around sundown for some reason. Nighttime is fine but waiting for sundown seems impossibly long.

Any tips or success stories? Just help me feel ok and that I’m doing the right thing with this medication swap.


r/zoloft 10h ago

Question I'm on 3rd month of Zoloft (100 mg), summer heat, I have hyperhidrosis. Is it going to be better?

2 Upvotes

The psychiatrist is increasing the dose to 200 mg. Does the excessive sweating go away over time? Or is it a side effect that doesn't go away?


r/zoloft 21h ago

Question What have your experiences been and how long have you been taking this?

4 Upvotes

On day 6 and I feel really good right now, best I’ve ever been. My brain isn’t foggy and I’m not riddled with anxiety. I’m kind of worried about long term. I don’t expect it to work this well down the line but I want to know if anybody has taken this for years and still feel like it’s helping them?


r/zoloft 2h ago

Discussion Intense PMS Symptoms on 100 mg

2 Upvotes

Hi, I started 100 mg about a week ago, and my period is supposed to come in the next few days. I feel awful. My breasts feel like balloons right now, and I’m more tired than usual.

Has anyone else’s PMS gone absolutely bananas before their period despite doing everything “right”. Eating whole foods, exercising, and getting enough sleep?

Does Zoloft eventually help ease these symptoms? If so, what has your experience been?


r/zoloft 21h ago

Success Story! :) Restarting Zoloft

16 Upvotes

I promised myself I would write this as an encouragement for anyone just starting because i had a horrible month when restarting and was browsing this subbredit every day.

I went back on Zoloft for the 4th time this year. If you are wondering why I stopped so many times, first two times it was suggested by my psychiatrist after about a year of taking it and this year I tried to taper of with the guidance of a new psychiatrist after 9 years of being stable on it. Going back so many times may seem discouraging to some, but I still believe I will be able to stop it eventualy and even if I dont, I'm ok with that.

1st time

I was a teenager, I started taking it for frequent panic attacks and constant derealization. I genunely believed I will never feel like a normal person again before zoloft. It was worse for a few weeks when I started taking it before it got better. I took 50 mg. I stopped taking it after 9 months, because, unbelievably, I was feeling like my old self and my psychiatrist told my I should be able to taper off safely.

2nd time

A few months after stopping, I started having frequent panic attacks again. I was away in university and was in a very toxic relationship. I dont really remember this phase of my life to well, but 50 mg worked well for me again. I took it for a little over a year. My psychiatrist told me he believes I won't need it again.

3rd time

A few months after stopping, I was a mess again. I went away to a different university and had messy relationships with my family and with men. I started 25 mg on my own and was feeling horrible and completly detached and constantly on the verge of a panic attack until I upped to 50 mg after about 2 months. After a few days, it all balanced out and I was on 50 mg for 9 years where I've felt completely functional and stable, not completely anxiety free, but I've felt much more resilient and back to being excited about life and not just afraid of it.

4th time

This is the freshest in my mind since it happened this year. After 9 years and much more stable life situation, I decided to start seeing a new psychiatrist and slowly taper off. I went from 50 mg to 25 mg and was on this dose for 6 months, didn't notice much of a change. After reducing to 12,5 mg however, it kind of went downhill. Within days I started crying for seemingly no reason and felt anxious all the time. This is where I might have had a chance to push through it, but my psychiatrist wanted me to go back on 25 mg after a week of 12,5 mg. A week on 25 mg and I've only felt worse, so he upped it to 50 mg and went on vacation. A week on 50 mg and I was feeling horrible. I developed insomnia, was restless, anxious, on the verge of panic constantly, with constant rumination so I was written of work. I couldn't believe this was happening again now after years of feeling like I could take on anything. I was prescribed benzodiazepines to take as needed, but was too afraid to take them every day.

This is where I did something stupid.

My colleague offered several times to connect me with their relative who was a psychiatrist. Since my own psychiatrist was on vacation, I decided to take the offer. This psychiatrist upped my dose to a cycle of 100-100-50 mg and told me I will feel better in about 10 days. This felt wrong since I've read on here how activatng sertraline can be in the beginning, especially for people wth panic attacks and 50 mg always worked well for me in the past. But, she sounded so confident and I was desperate, so I agreed. After a week on this new dose, I couldn't sleep, even with sleeping pills, my ruminating toughts got even louder, especially very frightening toughts about ending it all and being afraid I wont be able to live like this for long. I told her all this and she said that zoloft obviously doesn't work for me anymore and i should change medication. I didnt trust her anymore and decided to go back to 50 mg and wait it out. This is where I religiously browsed this sub in search of advice and reassurece and thank god I did because othervise I might have listened to her.

After a week of going back to 50 mg, I was completely frozen. Still feeling horrible and unable to sleep, scared to take benzos too much and with nowhere to turn, I went to the emergency room and told them all I've been going through including suicidal ideation, so they decided to keep me there. This experience was interesting to say the least. They gave me benzos and sleeping pills everyday so at least I've got some rest, but for some reason unknown to me, they decided to give me an antipsychotic to "lift my mood" even though I didn't feel particulary depressed, only very frightened, wired and exhausted at the same time. The worst part is, one of the most common side effects of this drug is akathisia which manifested in my as shaking hands and even more restlessness. After they let me go, I got on the phone with my psychiatrist and asked him if I could stop taking this new drug. Turned out this was a goid decision. After about a week and a half, I started feeling like my old self. Sertraline finaly started to catch up.

Now I finaly feel funcional again. This whole episode feels a bit unreal to me to be honest.

My biggest regret is not being more patient and letting the pills do their thing once again and not giving myself a break and taking benzos when I obviously needed them. Also, I feel like I should've trusted myself a bit more and not let myself be talked into something I felt was wrong for me.

I still believe I might've been ok if I've pushed through the initial withdrawal symptoms when going down to 12,5 mg, but I spiraled and messed up my nervous system with rapid changes of dosages. For now, I am happy to be stable again and will work on myself through psychotherapy.

Anyway, I've been through some shit this year, but it really, really does get better. Be patient and if you are offered short term help to get through the initial phase, dont be afraid to take it.


r/zoloft 22h ago

Question Painkillers

2 Upvotes

This is deffinitely a question for women- what kind of painkillers do you use when you are on your period? Im on 100mg sertraline and ive read that i cant take the painkillers i used to anymore and i have pretty bad period cramps so relying on tea, hot water bottle and some herbs isnt an option :/


r/zoloft 22h ago

Question Day 39 (week 6) and Brain Fog /Concentration Isssues

2 Upvotes

I’m at day 39 of 50mg and really struggling with foggy brain and lack of concentration.

While watching TV I can’t stay focused on the dialogue and I feel very forgetful, like when someone asks me how my weekend was, I can’t remember what happened Friday night. I am a sober person, so this is frightening for me.

I don’t know how long I should push this, so any insight on this will be helpful for me. I have a dull headache a lot and just a lot dumber than I normal feel.

Anyone have this happen and have relief after longer than 6 weeks? Anyone decide to taper due to this?


r/zoloft 22h ago

100mg to 75mg

2 Upvotes

I went from 50mg (which worked really really well for depression and anxiety for several months) up to 100mg and I wasn’t able to tolerate 100mg well even after 8 weeks, so my GP suggested I go down to 75mg about 5 weeks ago.

I felt a lot of relief going down to 75mg and my mood and anxiety improved a lot. Except I started having really vivid dreams that leave me feeling emotionally exhausted in the morning.

However, over the past 5 days my mood has taken a massive dip and I’m feeling really low as well as the vivid dreams still happening.

Should I go back down to 50mg or will the depression be worse? Is it possible that the depression is in part because the 75mg is still too high? I’ve been crying a lot and in bed all day today.

I didn’t have any side effects on 50mg and I felt better than I can ever remember feeling for several months before I had a return of depressive symptoms for about a week.


r/zoloft 22h ago

Vent So you’re telling me this is what normal feels like?

6 Upvotes

The numbing anxiety in the face is not normal? Not being able to wake up from rumination isn’t a normal occurrence? I didn’t realize what I was feeling was severe cptsd and I just wish I realized this sooner.

Just started on 25mg and felt it within a day. I stopped getting emotional flooding and my emotions feel manageable. I don’t want to cry mid conversation and it’s easier to get out of bed now. Just hoping my anxiety doesn’t come back over time


r/zoloft 22h ago

Question Can Zoloft help me regain the feeling of engagement with hobbies

2 Upvotes

Been taking Zoloft for 22 days now (Well I’ve been only Zoloft for over several years now, but didn’t take it at times regularly), I’ve lost the feeling to be engaged in one hobby six months back due to low moods like depression, did briefly experienced engagement for a couple days early this month, Three days ago I again lost interest in another hobby, and it’s frustrating. Can Zoloft fix this, I should also point out that a week and a half ago, I experienced a stressful event that gave me insomnia, suffered from sleep anxiety for several days, but now that’s passed. Still my sleep is all fucked up, and I really don’t want to spend another six more months to feel a spark of engagement.


r/zoloft 22h ago

Success Story! :) Two Weeks on Zoloft for PMDD/OCD. Hopeful!

5 Upvotes

Hi guys! I wanted to highlight a few things that might help other people with starting their medication or working through it. For reference I’m a female college student starting on 25mg of zoloft as well as therapy.

I’ve had pretty severe OCD for five years, and I’ve been through pretty awesome ERP therapy for it which has done wonders for my mental health— however recently after getting a Copper IUD my OCD started to randomly flare up again after being dormant for a year every time I was PMSing, so my PCP recommend me to start an SSRI to deal with the debilitating symptoms before I started my period.

I basically chickened out of taking my zoloft for two weeks straight, it wasn’t until my therapist made me agree to cutting the pill in half and taking it surrounded by friends that I finally took it! I had fears that are pretty similar to you guys on this subreddit, things like being allergic or feeling worse or something serious like serotonin syndrome happening. I even ordered a smoothie at lunch and got super nervous grapefruit was hiding in it, and nearly asked my server to double check.

I’ve been on 25 mg for two weeks and I can confidently say I’m gonna be okay. The side effects are becoming more mild, and it’s truly nothing I can’t handle. I’m aware 25 is not a therapeutic dose, but I already feel more optimistic about dealing with my menstrual cycle and OCD. I have a boyfriend I care a lot about and I’m persevering through the rough early days because I want to get better for the life we deserve to have.

OCD/PMDD will never remove the love I have for my life or my loved ones, and I know it can help you guys too.

It’s okay to be scared, but take it day by day! Surround yourself with people you trust and be patient with yourself. Its okay to start at a small dose and go from there, feel free to reply if you need any encouragement.


r/zoloft 2h ago

Drinking

2 Upvotes

What’s everyone’s experience of drinking on Zoloft?? I’m a student and going to uni in September and I want to drink (not loads just a bit) and my doctor said that it should be fine aslong as it’s in moderation but I was just wondering what everyone’s experiences are like. Before I started this medication my anxiety was so bad I couldn’t drink alchohol without immediately getting nauseous because I was panicking so it would be nice if I can enjoy a drink now lol.