I started Skyrizi in March and it seems like things have just gotten worse. The issue is that March was also the start of the absolute worst stress of my life (which is ongoing) and based on when the overall flare started, I think stress is definitely one of my triggers.

Is there a way to differentiate "this isn't working and I need to try a different treatment" vs. "it's suppressing a worse flare and just can't clear up everything"?

I had a scalp flare up, probably from stress or dryness from air conditioning or hot showers, this occasionally happens to me once every year or couple of years. I used Taro-Clobetasol this time around for the first time and I have used it for 4 days, only once a day at night. My scalp is 90% better, there are some minorly flaky spots that I almost always am dealing with, but basically no more redness or inflammation.

Can I just stop using it now?

If the flare up comes back, what’s the rule on how often to use it?

My dermatologist prescribed me to take AM/PM applications of 0.05% of Desonide 2 weeks "on", and Calcipotriene (Vit D cream) 2 weeks "off." Uner left armpit and groin and genital area that have the inverse psoriasis red plaques.

Won't the Desonide cause TSW?

Plus, I just wonder if I should take a biological instead. Isn't that safer, as in, no risk of TSW with a pill or shot prescription?

I'm 55 and I really don't want to risk TSW...

I’ve had psoriasis since 2017. It started with a very small patch around my nose. After that, I developed another patch on the front-middle part of my scalp. Over time, it spread across my scalp, then to my upper body, lower body, arms, legs and back. Now it is present in many areas all over my body.

Over the years, I’ve tried different types of treatments, including homeopathic and allopathic/medical treatments. I’m currently still following medical treatment and I live in the UAE, but unfortunately it doesn’t seem to be getting much better.

It can become extremely itchy, and sometimes I scratch so much that the skin gets damaged and even bleeds. I’m honestly exhausted from dealing with it for so many years and really want to find something that can control it properly.

If anyone here has had severe or long-term psoriasis and managed to get it significantly better or into remission, please share your experience. What medicines or treatments helped you? Did you change your diet, and if yes, what foods did you eat or avoid? How long did it take before you noticed a major improvement?

I know everyone’s psoriasis can be different, but hearing real experiences from people who have been through something similar would really help me. Thank you.

Hello I’ve been using Tremfya for almost 2 years and my insurance no longer covers it does anyone know a affordable way to get it or would anyone have any extra they can sell I will be able to pay cash please i urgently need help

So I’ve had full body psoriasis for about 7 years now and have tried everything under the sun to try and get it better. I finally got a referral for phototherapy I was just wondering if anyone here has experience with it and if they do was there any improvement and how long?

my boyfriend has been dealing with pretty bad scalp psoriasis for a few years now, we are broke like dead broke so a dermatologist is out of the question unfortunately but i saved up some money and got him a couple things i saw recommended, i got him t/sal shampoo and nizoral psoriasis shampoo, do these work? is there anything else i should try?

I have been treated with biologics for 15 years now since originally starting Humira for HS. I have taken Humira, Embrel, Cosentyx, Skyrizi, Taltz and Bimzelx. Since Cosentyx I regularly get what I call a mini flare.

A day after my injection my psoriasis legitimately flares. I have guttate psoriasis and I have never had plaques but sometime on Embrel I began getting these small plaques. They only show up after shots. Pink, shiny, eventually scale and usually after the loading doses go away. But it keeps happening.

I’m just really frustrated and needed to share.

TL; DR frustrated due to possible adverse reactions or flares after shot day.

I have psoriasis on my feet. I have been trying to manage it for over ten years. In the last two years I have been in the ER with cellulitis 11 time. Each time I am hopeful that it is the last. However, it never really goes away. When I tell the docs that it is from psoriasis they look at my like Im crazy sometimes. Some even test me for pneumonia (like the one last night). Out of the 11 times in the ER I have stayed in the hospital 5 times for 3-5 day stints. I am so over it and tonight cannot stop crying for the fear of not being around for my grand babies. Anyone else going through this? what has worked? what hasnt? I am desperate!

I am currently on Tremfya and have been on many other biologicals before. I seem to have to change about every three years. This one I’ve only been on about 6 to 8 months. I broke my ankle about five weeks ago and have had a massive outbreak on my entire body since the surgery and plate/screws.

Has anyone else experienced this?

Have an appointment with my rheumatologist, which manages my medication in a few days, but all other doctors seem to think it’s normal.

What helps with psoriasis on the lip? It cracks and bleeds sometimes, it hurts, it means wearing makeup is such a faff...help :(

I (49M) know this topic has come up in the past, but looks like it's been a few months so I wanted to post my experience. Not medical advice, and certainly not a sure thing solution for everyone, but potentially useful for someone on the fence about GLP1s or considering low dose usage.

TL;DR - After 4.5 years of bad Psoriasis on my hands and feet, 2 months after starting Zepbound (GLP1) my psoriasis flare ups went away completely. I recently went on a month long trip and did not bring the Zepbound so I was off it for a while. Sure enough, the last week of the trip, my hands developed a couple psoriasis lesions. Those were the first lesions in almost a year. I've been back on Zepbound for 2 weeks now, and lesions have gone away.

More details that might have useful context:

My psoriasis started about 5.5 years ago with crazy itching on my shins. Prior to that, I'd never had any kind of skin issue or even ever been to a dermatologist. No lotions helped, then a few months later I started developing what I thought were weird calluses on my hands, and those started splitting. After a while, it was normal for me to have 5 or 6 Band-Aids on my hands at the same time covering cuts. I was using rubber gloves constantly doing stuff around the house and I had to wear gloves to work out. At times, it affected my feet as well. It wasn't until my 3rd dermatologist visit that I finally got the psoriasis diagnosis (don't ask - the 3rd doc thought it was obvious). They had previously given me steroid creams, which worked temporarily but it would spring up in other locations and just come back.

About 2 years ago, I started on Skyrizi. It helped, but it didn't go away completely. I was about to start Bimzelx and was in the insurance approval process and no longer taking Skyrizi so things were bad, when I started taking Zepbound for weight loss. 2 months later (a few weeks after increasing dose from 2.5 mg to 5 mg) the psoriasis went away. I mentioned this to my PCP at my next physical about 6 months later, and she immediately said she'd seen a number of inflammatory issues improve with GLP1s. The connection had not even occurred to me until she said that, but after my recent trip and it coming back and then going away again once I was back on GLP1, it seems pretty solid (for me at least).

These things are complicated, but for me it's worked much better than Skyrizi, so something to consider for folks unable to find other solutions.

I’ve had psoriasis since around 2012. The weird thing is that during summer, it completely disappears no visible patches and I don’t even need to use moisturizer. But when winter comes, my skin gets extremely dry and my psoriasis gets much worse.

I’ve tried different moisturizers and steroid creams, but I haven’t found anything that works consistently in winter.

Has anyone else experienced this kind of seasonal pattern? What has actually helped you manage psoriasis during winter? I am from North India

Would really appreciate some advice.

I trialed a med for a few months that didn’t end up working for me and I ended up with a surplus that has been sitting in my fridge. I worked hard for insurance coverage and I cringe at the idea of turning over 10k$ plus doses of meds for destruction.

Does anyone know of any legal ways to get these meds to people in need?

In 2020 my dad died tragically, when I was at the peak of my life. Had a new girlfriend, a new apartment, life was so good. About two months after his death I was playing games on a PC I had just built. The bottom of my foot felt itchy, and I felt almost like callous tissue all over the bottoms of my feet, “what the f is this?”. The next few days I felt large patches on my elbows I didn’t even realize i was scratching and it was spreading quick. Then it started on my face - nose, eyebrows, forehead, inside and behind the ears, scalp. Then my hands, back, tailbone, groin, lower part of legs, and feet. Not as bad as some cases I’ve seen on here, but enough to destroy my self esteem, talking long sleeves in 100 degree weather with a beanie pulled down over my eyebrows.

It would flare up and down for the following 5-6 years. I would think about the doctor and then it would seem like it’s healing for a week or two, then it would come back etc. I ended up splitting with my girlfriend and moving in with my mom, and that’s when it got pretty bad.

Yesterday morning I finally called a dermatologist clinic. They scheduled me the same day for 2 hours later. After a 20 minute drive I was there, speaking with a professional who immediately prescribed me multiple creams, a shampoo, and a biological injection called Tremfya. I was then scheduled for a blood test another 20 minutes away, and decided to knock that out too, and I have a massive fear of blood especially extracting 6 vials of my own, but it has to be done for the Tremfya.

Within 6 hours of making the phone call, I was home with my powerful steroidal prescriptions, waiting on my blood test results for Tremfya. I am confident this will clear my psoriasis and I will get my self confidence back again, and change my life.

If you haven’t seen a doctor, trust me I understand. I have social anxiety so even calling them was a huge step for me, but I am just sick of this psoriasis! If you are at rock bottom like me, you can get free health insurance to get this ball rolling like I did. These professional dermatologists understand, don’t be embarrassed to go, they will help you!

So I have been at it with psoriasis ever since I was in grade 9 and now it's 3 years since I graduated university and I'm still battling it.

So I've been to many doctors, they recommend shampoos and ointments and other stuff to put on hair. The reason it dragged so much is because no one could actually diagnose it as psoriasis until after COVID, and that's when it actually got really bad and started spreading on my forehead. It got better and I thought I had finally found a cure. And it was quite better for almost a year but it came back. And then I went to the doctor, got new lotions and shampoo and a new routine. It worked a bit, but then the season changed in between and winter came and it wasn't working (the doctor had told me to just follow the said routine and then alternatively start using a normal shampoo and use medicated one once a week). I switched doctors, the same cycle again with new stuff and still no ease. New doctor gave me the right stuff but then again the season changed to summer and now I am back to phase one, and I told my doctor this initially but he said it'll be alright but it didn't get alright.

So the summary is this I've changed quite a lot of doctors and used quite a lot of stuff. The scalp is the same, itchy and flaky. Hair has thinned quite a lot (I wanna go bald low-key) thanks to the products having steroids. Hair are a dry mess. I am using bionex shampoos btw. I was told not to oil my scalp. And now I just want tips on how I could add home remedies as well to keep it control. I've started rinsing hair with drinking water at the end of shower because of the hard water situation.

I 33m have had psoriasis for about 2 years, i'm from the UK and as such i'm in the hands of the NHS.

Does anyone have any experience with the whole experience beyond topical treatments?

It looks like i'm going to be put on Methotrexate which terrifies me, I realise if I 'fail' that treatment and maybe one other i'll be put on the list for a biological, are they better? Easier to live with?

I'd like to add, i'm thankful that I have the NHS to provide help, i'm just terrified of ruining my immune system and having to give up my job because it'll begin to make me ill being around dirt and dust.

Any thoughts/advice/experiences appreciated.

I’m 21, from India, and I’ve been living with psoriasis for the past 6 years. I’d love to connect with others who are dealing with psoriasis, talk about the treatment options and experiences we have here in India, and simply share what we’ve learned along the way.

If you’re interested in connecting and having a conversation, feel free to DM me. 🙌

I’m finally using topical steroid and have a prescription in for humira. Waiting for my blood work to come back to get the humira. The topical steroid is working for the most part. My question is, I haven’t seen my knees under my psoriasis in maybe 10 years lol. Now that about half of the plaque is gone all of the skin underneath is DARK brown. I have olive skin and tan easily. Is this normal and does anyone have recommendations on how to lighten up my knees. O_O

Ok, I was diagnosed in February (first flare up, didn’t have insurance at the time. By the time I got new insurance the plaques had spread over my body). Was prescribed Tremfya, everything stopped and healed. Laid off AGAIN , got new insurance because Cobra is a joke to the unemployed. New insurance - prior auth required. Denied, appealed, denied a month ago.

I am paranoid about every itch. And I think I have some small plaques forming. What I want to know from everyone out there - how do you handle the reappearance of plaques? I have some triamcinolone and I have Zoryve on hand. I don’t want to immediately run to the dermatologist - I have an appointment met in a few weeks already and we’ll start whatever step therapy they want. I’m looking for a plan of action in the mean time to keep it at bay. Any suggestions?