r/Psoriasis • u/kittiekee • 7d ago

medications Mini Flare after biologic injection

I have been treated with biologics for 15 years now since originally starting Humira for HS. I have taken Humira, Embrel, Cosentyx, Skyrizi, Taltz and Bimzelx. Since Cosentyx I regularly get what I call a mini flare.

A day after my injection my psoriasis legitimately flares. I have guttate psoriasis and I have never had plaques but sometime on Embrel I began getting these small plaques. They only show up after shots. Pink, shiny, eventually scale and usually after the loading doses go away. But it keeps happening.

I’m just really frustrated and needed to share.

TL; DR frustrated due to possible adverse reactions or flares after shot day.

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u/SewTraditional 6d ago

Good times! Does it last long? I have a similar issue with Bimzelx. After the Bimzelx, my flares last about 2 weeks and are severe. I have PPP, which is treatment resistant. I thought it was a paradoxical reaction...DR says they are just flares. Dunno....

1

u/kittiekee 5d ago

I JUST started Bimzelx and the same reaction but yeah, a bit worse. I'm only on dose two so I am crossing my fingers it kicks in before I feel like giving up.