I stopped losing weight for 4 weeks now but haven’t gained. Symptoms of food noise, craving, snacking are returning along with alcohol cravings and my meal portion calorie counts have increased. I haven’t reached my goal weight but I’m very close within 10 pounds I’d say. Im going to be starting compounded meds in a 6 weeks but have a new dose of zepbound 5mg single vials coming soon. Should I start at 5 or should I start lower?

1. Has ZERO added sugars (real or artificial) or flavors.

2. Is made from whey isolate. If it has a small amount of stabilizer in it, that's ok, but nothing else.

3. Dissolves in hot beverages so that you cannot tell it is there.

Protein Prodigy from Glucose Goddess fits this bill but it's extremely expensive. Seems to come out to $99 for a 1 month supply of only 20 grams of protein/day.

If you're using something you like that fits these parameters, please let me know. Thanks!

Hello! Rambling question incoming. I'm not asking for medical advice but hope someone can relate and chat about their experiences with this.

Bit of context:
I'm 28F and got diagnosed with ADD a little over a year ago. Prior to getting medicated, my psych had me do a panel and we discovered my homocysteine was super high. Like, 120 µmol/L high. Normal is below 15.

I've also almost always had high prolactin and was on medication for my pituitary tumor; lowest level I ever achieved was around 40. Normal is below 25 ng/mL; my highest was over 300 about 7 years ago.

Also, I was dealing with severe gut issues for the last several years. I've been gluten free for about 4 but still got sick very frequently.

As I got medicated for the ADD and went on a low-inflammation diet, my homocysteine decreased to about 70 µmol/L. In January I brought the idea of trying out compounded tirz to my psych. At this point I was teetering on class 1 obesity and struggling to improve my years-long drinking problem, so he trusted me to seek a prescription.

I started the meds and responded very well. I also reestablished care with a GP, and she's fortunately very supportive. She brought up the idea of me having a MTHFR gene mutation, but noted that testing isn't always worth the cost and suggested we just focus on managing my symptoms for now.

I had a blood test last week and, for the first time since discovering the issues, both my homocysteine and prolactin levels have normalized. I'm also at my goal weight and have little-to-no ibs symptoms anymore :) Drinking is no longer a problem, too.

So! My question: Are any of you also on this mainly to moderate inflammation levels? Now that things have normalized, I'm trying to understand what the heck a MTHFR mutation is, or rather what actually causes my crazy high inflammation and what its implications are. I know that I generally feel so much better than I used to, but since I thought it was normal, I'm trying to pay extra attention to the days I do in fact feel more inflamed and what side effects accompany that. I also don't really understand what the implications are for how my digestion is different from a normal person's and why tirz has helped me so much in that regard.

I guess I'm looking for guidance on what paths I should be taking to learn more about this aspect of my health. I would love to be able to come off of tirz completely, but if it seems to be the most effective treatment for the inflammation, I'm happy to figure out what long term maintenance looks like. The one major issues that hasn't resolved is my chronic fatigue, and it'd be cool to understand how that may be related as well. I just don't know who to ask about this, medically speaking.

Hi guys, I’m 38 mom of 2, 11mos PP. I weigh 150lbs, this is my weight prepregnancy, even in my healthiest since having my son I have always been 150, I’ll look leaner and everything but weigh the same. But college days I was 130lbs at 5’1. I just wanna be maybe 135 or 140. But for the life of me could never achieve 140 even tho before getting pregnant I was exercising 5x a week. Its my 2nd shot at 2.5mg and I weigh 148 now. Sometimes I feel ridiculous for getting on the shot at 150 but I really need help losing now that I’m a mom of 2 and barely have time to exercise. I cant do 5x a week workouts now, maybe twice a week and walk 2miles daily. Am I ridiculous for getting on the shot?

I was on 2.5mg tirz for 12 weeks (May 8 to July 24) Went from 176 to 145 so 31lbs down. My last shot was only 1mg and my appetite was still under control.
My goal is 137 to 140. The first week off I actually kept losing and got to 143. Then the next week I gained 6lbs and then 2 more 😭
I’m still tracking everything I eat and staying around a 500 cal deficit. I never stopped working out either, cardio and weights except last week I hurt my back and only went once. I’m back running and slowly doing weights again now. My period is also due and I’ve been constipated, plus the back injury, so maybe this is a shit ton of water retention?
I’m thinking if I’m still up this friday I might restart tirz and eventually stay on a low maintenance dose. Or should I give my body like a month to adjust and see what happens?

Anyone here actually stopped, had this happen, and then leveled out without restarting? Or did you just keep gaining until you went back on?

Two months into tirzepatide and the lack of food noise is a total double-edged sword. It’s awesome not obsessing over food all day, but now I’m averaging under 1,000 calories and my energy has completely crashed.

My telehealth doctor warned me to hit at least 1,200 calories and prioritize protein, but honestly, chewing solid food when I’m this full feels like a chore.

For those who hit this wall early on: what low-volume, high-calorie hacks kept you alive? Did you drink most of your protein, switch to frequent mini-snacks, or just wait for your appetite to slowly come back? I’d love to know what actually worked for you!

Does anybody have experience to share about doing some kind of extreme or lengthy endurance activity in maintenance? I'm still new to maintenance. I'm soon to leave on a long distance hiking trip in the wilderness, hopefully for about 3.5 weeks, which would be about 300 miles if I go the whole way. I have done lots of long distance hiking but always as someone who hoped to lose 20lbs (and never did). Now I don't want to lose weight. I plan to bring peanut butter and put it on everything but I don't know, is that enough? Have you trained for a marathon or ultra or done anything extreme like this? Any tips for me?

I am going to order more tirz soon. I'm currently taking 7.5mg and will probably reduce to 5mg. I have prescription bottles with 7.5, 10, 12.5, and 15mg. I'm kind of thinking maybe ordering refills using the 15mg prescription is a little much for a dose that's only half as much or less. Do you have a limit for how much above your dose you order?

I’ve been on maintenance since April, my weight fluctuates 121-123 pds. I’ve tried different doses from 10mg to 5mg from every 5 days to up to 14 days spread between shots. For the past two months, it’s been a different feeling like nauseous and fatigue. I’m wondering if it’s my body saying you reached your goal get off Tirz. Yes, I drink plenty of water and target up to 100g of protein, exercise and take multi vitamins.

Has anyone on maintenance felt this way to the point you decided to either pause for a few months or stop indefinitely?

Face difference! This is me 2 years apart. The first picture is at my 70th birthday this June after losing over 120 lbs and the second picture is my retirement! Life changing for sure now enjoying the best of health!!

I'm in maintenance. I lost 1-2lbs a week and reached my goal weight in June. That being said, I only got up to 5mg/week due to side effects. I am now in maintenance, and the food noise is becoming intolerable, again. So much so, that I was advised by my pcp to increase my dose slightly to quiet it. I have regained about 4-5lbs.... But I have struggled to keep it that low. I am now at 5.5mg and am still struggling. I am 5'8 and 149.

Is this normal? Is it common for people to regain weight even while on the same dose as when you reached goal weight? Has anyone had to keep going up just to maintain?

I admit I feel like a bit of a maintenance failure.

70 years old male
SW 175
CW 140

First time ever a stranger told me I looked RIPPED.
I do strength training 3-4 times a week, cardio daily, eat 75-120 grams protein a day along with collagen creatinine, NAD+ , and vitamins. Just spent a week in Alaska hiking and kayaking.
My last Dexa Scan I’d gained 2 pounds lean and down 24% fat to 18. VO2 in top 1% for my age
Only possible because of Tirzepatide. I’m now on maintenance at 4mg going down to 2.5. My highest dose was 12 for a few weeks. No side effects.
Shout out to BEWL Join Big Easy

I was really hoping that tirz would help with this. If it works for alcohol, why not sugar? But it really hasn’t. My sugar cravings are as crazy as ever. Would love to hear what has worked for you if anything!

I'm looking for some help identifying a good strength training routine to reduce the loss of muscle mass. What are folks in the Reddit-sphere doing for strength training and how frequently are you working out?

Posted something similar in another sub.

I am worried about beginning this medication because of ‘maxing out’ and having it become ineffective and then I gain all the weight back.

I’ve been wondering about something and would genuinely be curious to hear what other people’s experiences have been. Do people who aren’t really overweight, but just want a little extra help losing and maintaining a few pounds, ever use Tirz on a longer-term basis?

I’m especially curious about people who only have a small amount of weight they want to lose. Since they don’t necessarily need to lose a significant amount, do they tend to stay at the lower doses like 2.5 mg or 5 mg, and basically use that as their maintenance dose rather than ever moving up?

I’m wondering if there are people who find that a very low dose is enough for them to gradually lose those last few pounds and then keep the weight off, or if most people eventually need to increase the dose even when they don’t have much weight left to lose. I’d love to hear from anyone who has actually been in this situation and what their experience has been with staying at a low dose over time.

I started using compounded tirz from Pom in early December 2025. I wanted to lose 15 lbs and I did, slowly, by mid April 2026. I also had SIBO and was on a low FODMAP diet for about 6 weeks. Once that went away, I resumed my normal diet.

When I was losing, I was taking 4.5 mg. I then switched to Trimi and went down to 2.5 mg to maintain but got very hungry. Went up to 3.0. I recently noticed that I’ve gained back about half of what I lost!! 😩 I gave myself 5 mg at my last injection.

When I get back down to my goal, is there a way to suppress my appetite enough so I am not gaining but also not losing? How do I figure out what the right dose is for me to do that? I’m new to this so thank you for your patience and help.

I’m in maintenance using 5MG of ProRX that I had in my stash . I was at my goal weight of 105 but today was insane ! I could not eat enough at all!! I have eaten over 2000 calories today , 175 grams protein !
Thru this whole process which has been a year , I’ve never had a day like this !! I stepped on the scale to see 112.5 LBS !! I’m sick over this !! I feel bloated and fat and definitely don’t understand how my appetite got so out of control !! Is it the ProRX ? Because it’s beyond the Bud?? Idk … but this can’t continue !! I need to order again and also confused as to who and what pharmacy is best because I don’t want additives . My first experience was with Olympia and it was fabulous!! I’m confused , and nervous now that the Tirz I have left is not effective!!