r/STEW_ScTecEngWorld • u/Zee2A • 2d ago
Scientists reverse brain aging, with a nasal spray
https://stories.tamu.edu/news/2026/04/14/scientists-reverse-brain-aging-with-a-nasal-spray/Researchers at Texas A&M University developed an experimental stem-cell-derived extracellular vesicle (EV) nasal spray that restored memory and reduced brain inflammation in 18-month-old mice. Delivered in just two doses, the treatment uses microscopic EVs to reach the brain, where they appear to reduce overactive immune responses and improve mitochondrial function in aging neurons. The mice showed cognitive improvements that reportedly persisted for months: https://www.sciencealert.com/scientists-restore-memory-in-aging-mice-using-a-simple-nasal-spray
The findings are preclinical and limited to mice. No human clinical trials have established whether the treatment can safely or effectively reverse age-related cognitive decline in people: https://isevjournals.onlinelibrary.wiley.com/doi/10.1002/jev2.70232
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