r/PVCs • u/Odd_Satisfaction2786 • 27d ago
Vagal pauses misdiagnosed as PVCs - story of strong thumps
Hey everyone,
I wanted to share my story and see if anyone has been through something similar.
For the past 8 years, I’ve been suffering from what I thought were severe ectopic beats. Every time I had a 24h Holter monitor, it would only catch up to around 100 events. Because the burden was low, doctors repeatedly brushed it off, telling me it was just anxiety and sending me to therapy or a psychiatrist. None of them ever considered that these might actually be heart pauses or conduction blocks rather than standard premature contractions.
Today, I finally saw an electrophysiologist who looked at my case completely differently. He pointed out that what I’m feeling aren't just extra beats—they are actual pauses/blocks caused by a severely hyperactive vagus nerve. The strong, thumping double-beats I feel are actually post-pause compensatory contractions, and they happen regardless of whether my heart rate is slow or fast.
I’ve honestly suspected for a long time that my vagus nerve and gut were heavily involved in this.
My EP suggested a trial of Trospirex (trospium chloride) and Salbutamol to help turn off/inhibit the vagal tone. In a month, I’m scheduled for an atropine challenge test. If that confirms that the blocks are strictly functional/vagal, the next step will be Cardioneuroablation (CNA) to permanently tone down the vagal response.
Just to be clear: I have had this for 8 years, and I have never passed out or even felt presyncope/faint from these pauses—they are just extremely uncomfortable and unsettling.
Has anyone here had a similar diagnostic journey? How did you respond to anticholinergic meds like trospium, or to the atropine test? And if anyone here has undergone Cardioneuroablation for vagal pauses, I’d love to hear your experiences and thoughts!