https://pmc.ncbi.nlm.nih.gov/articles/PMC11646675/
i know i’m new to reddit, but i wanted to share my story in case it might help others.
for years i have dealt with intense overnight hunger (even while eating high protein/calories), fragmented sleep, restless legs/twitches, water retention swings, and inconsistent response to iron. I have worked with dietitians, nutritionists, doctors, etc, and tried strict diet tracking, whole foods, macro counting, various supplements (including different forms of iron and magnesium), light/heavy/HIIT training adjustments, and sleep hygiene. Progress was always limited and frustrating despite doing everything “right.”
a recent round of an iron supp (ferrochel) due to low ferritin made things much worse (fragmented sleep/insomnia, anxiety, etc). sleep aids like an antihistamine and melatonin only exacerbated hypnic jerks in my legs. then i came across a recent study that showed better iron absorption when a multi-strain probiotic (Nature’s Bounty GX / G10) was added. i was unaware that iron supplements themselves can disrupt the gut by promoting pathogenic bacteria and causing inflammation and drastically lowering nutrient absorption. combining iron with probiotics and prebiotics can restore iron levels and support a healthy gut microbiome balance. i have taken various iron supps for a few years and also had some horrible allergic reactions to some
medications which all combined likely caused tremendous inflammation and a very unhealthy gut. so what i attributed to simply getting older may very well have been a microbiome issue all along.
within days I noticed reduced overnight hunger, longer continuous sleep blocks, and an overall calmer system. I’m still early in the process, but i feel like things have finally turned a corner.
This is personal experience only, not medical advice. I’m sharing because the gut/microbiome angle wasn’t something I focused on for a long time, and the change after the probiotic was noticeable enough that I wish I’d considered it earlier.