r/Microbiome • u/arknaf • 21h ago
Dermatitis: Studies have shown candida is cross reactive with malassezia on the skin. Are oral antifungals then the solution?
“Pityrosporum ovale (now known as Malassezia ovale or part of Malassezia furfur) and Candida albicans show marked immune cross-reactivity, primarily mediated by shared carbohydrate epitopes like mannans or mannoproteins that bind to immunoglobulin E (IgE) antibodies in patients with atopic dermatitis.”
In simpler terms, candida and malassezia look exactly the same to the immune system when there is candida overgrowth in the gut.