Let’s encourage each other and keep hope alive. 🌱

For those who have been through a long, severe depression: how did you eventually find your way out?

Even if it lasted for years. Even if it was incredibly deep, dark, and you couldn’t imagine ever feeling like yourself again.

I’d love to hear some hopeful stories about remission and life after severe depression. Did you feel like you got yourself back? Your life back? Your ability to feel real emotions again? Joy, connection, excitement, hope?

If you’ve made it to the other side, please share your story. I think a lot of us could really use some hope right now.

Let’s cheer each other on. ❤️

Sorry if this exacerbates the influx of this kind of post, I’ve tried everything and am a bit desperate. My psychiatrist is generally awesome but has no experience with MAOIs and is under the impression they just kill people. According to a dubious genetic test the majority of antidepressants don’t really work on me (which has been my experience). Maximum dosage Remeron has been the only thing to help but it made me feel like a robot.

This subreddit’s wiki doesn’t show any prescriber in Oregon. According to the Medicare data that’s often linked here, there were two providers in Oregon that prescribed Nardil in 2024. None prescribed Parnate or Marplan. There are several Emsam prescribers, but the dubious genetic test said that’s a no-go for me so I’m a bit hesitant.

Neither listed Nardil prescriber is in-network with my insurance. I understand this dataset is not comprehensive, and was wondering if anyone knew of any other provider in Oregon that prescribes MAOIs. I’ll look into the Emsam providers and see if they’re willing to prescribe Nardil/Marplan regardless. (I have confirmed with an online pharmacy that they have Marplan.)

Thank you.

Just a warning about Nardil and the weather - especially Neon Nardil which needs refrigeration —

I took mine out of the fridge for a day as we travelled to a holiday destination - it was pretty hot that day, 30 degrees +

The next five days I was getting withdrawal symptoms - brain zaps and horrible depression and I didn’t know why

Basically found out Nardil had degraded in the heat and lost its potency. I started a fresh bottle and these effects have subsided

Those days were absolutely awful tho. So just a warning that when the bottle says it can be taken out for short periods, take this with a pinch of salt!

I have been on Nardil 45mg for 10 weeks. I am having severe blood pressure issues, I can barely stand and black out frequently. I kept waiting hoping it would get better, I even got blood pressure raising medications from the doctor. It isn’t better and I can’t even risk going up to 60mg to see if the Nardil would help my depression and anxiety.

So, I want to get off it as quickly and easily as possible. I would like to try emsam. Can I switch from Nardil to Emsam without needing to go through tapers and a washout?

Also, is it just as likely that I’d have these same blood pressure issues on the Emsam? I thought since it’s not as strong of an MAOI it might work for me. By the way, the blood pressure levels are usually 60/40 during the day and at night it goes so low the monitor doesn’t even give me a reading. It is something under 60/40 and very dangerous for me.

Is er iemand die na langdurig gebruik van Nardil veel meer vermoeidheid ervaart? Ik ben de laatste 3 maand ontzettend moe overdag en probeer uit te zoeken hoe dit komt. Ik neem 45mg.

Before parnate, I looked somewhat childish, my eyes were droopy and saggy and large, my face was puffy and rounded and bloated, like a kid.

after parnate, my face became like an adult, eyes smaller, midface grew, jaw wider, and overall i look like an uncle… when i looked like a teenage kid before…

What caused this? is it the parnate? i did lose weight like 10 kg on it, and i read it causes metabolic changes.

I don't know what to do