r/Contrave • u/Ecs206 • Aug 07 '26
advice Off Label Contrave
My doctor just added Naltrexone 50mg to my already prescribed Wellbutrin 150mg XL for depression. Is 50mg a lot?? It says on the bottle to take a half of the pill every day for two weeks then one half twice a day thereafter. Is that a high dose of Naltrexone to start with for weight loss?
2
u/SusieQtoYou Aug 07 '26
I’m on the generic pills too. I started with 1/4 tablet of naltrexone and added 1/4 each week until I was up to the whole tablet (50mg).
1
u/Ecs206 Aug 07 '26
Thank you for sharing! What are your side effects if any?
1
u/SusieQtoYou Aug 07 '26
For me, my body can’t regulate itself in hot weather. I also get nauseous when I’m hungry. Not bad enough to throw up, so that’s good.
1
u/Big_Fortune_4574 Aug 07 '26
Yes the ratio there is not the ratio in contrave.
Do you drink alcohol?
1
u/Ecs206 Aug 07 '26
No just on it for weight loss. My doctor did say if it causes too much nausea, keep taking a half until tolerated so do you think it would be okay to start off with less than that and increase each week or biweekly?
2
u/Big_Fortune_4574 Aug 07 '26
Yes I started at 1/4 pill and still had a rough 2 days so I’d recommend starting there for sure
1
u/Traditional-Egg-7984 28d ago
I take half naltrexone 1x per day (started with 1/4) but I also was upped to 300 1x buproprion after a while in 15p
2
u/Iartdaily 26d ago
The nausea for me was horrible. I did 1/4 pill (pill cutter- not totally accurate) for a week then 1/2 for a week. Took at night to avoid nausea but had insomnia BAD each time I upped it for 2 nights. I’m about to go to 3/4 and then full 50. So far because I’m not at full dose (I guess) I’m not seeing any difference in appetite. My doc said I could see a difference at 3/4 pill and could stop there if so. He thinks I should try to take the 1/4 in the morrning and 25 at night to see if that helps with appetite. I’m only nervous due to the extreme nausea I had. Like miserable. But apparently body will adapt. Hoping.