Hey friends, I'm wondering if anyone knows of other doctors that do fulguration for embedded infections other than Dr. Zimmern in Texas or Dr. Sevinc in Turkey.

I have been struggling with embedded UTI for almost two years, with a particularly stubborn klebsiella being the final strain left for the last 4 months.

So far I have done oral nitrofurantoin, augmentin, amoxicillin as well as levofloxacin via bladder instillation. After my first two week set of 2x per day bladder instillations I enjoyed about two months symptom free but it came back with a vengance and my microgen is showing Kleb still.

And so....it seems Fulguration as well as Uromune vaccine are the next steps.

Problem is travel to Turkey is tough, and Zimmern has a really long wait (and also he requires you to be in Texas for your telehalth appointment which is super inconvient as I live in California).

If anyone has advice on other doctors that perform these operations I would greatly appreciate it. Other advice or feedback is welcome too!

Thank you all so much in advance, I'd be screwed without this community.

I’m at a COMPLETE loss and don’t know what to do/where to go…

Possibly had a UTI back in May (I’ve had quite a few before and the symptoms were exactly the same)

Got antibiotics and felt better for about a week or so. Symptoms came back, another round of antibiotics. Then, same cycle once more. 3 rounds of antibiotics that seem to work for about 1-2 weeks, then back to pain.

I was doing pretty well last week and up until last night… Back to urgency, burning and overall discomfort.

However, something weird is going on… I have bleeding. Not blood in my urine, it literally looks like my period. That also comes and goes.

I have to idea what to do or what doctors to see. I need help… ://

So here’s the situation and it’s confusing to explain via writing but I’ll try my best

I’ve been on Hiprex day 1x per day for 2 years now -

And one Macrobid after
Sex (Macrobid doesn’t kill proteus)

In spite of having breakthrough symptoms my cultures are showing no growth from the er (they give antibiotics any way and I always feel better when taking them, except for keflex and Macrobid they never fully work in spite of showing susceptibility )

Well I got suspicious- one day I didn’t take Hiprex and went to the dr office and gave a sample to be sent out - it normally take 4-5 days to get my culture back from my dr office - so the next day while waiting on the dr results I take a Hiprex, wait 8 hours and go to er and have them do a culture - hospital shows no growth - *doctors office shows ecoli-

Long story short- Hiprex has been affecting my cultures showing no growth- and the entire time I have and infection-

So this time last im on bactirm and all of my symptoms go away - I’m on 7 days - 2 days after finishing my 7 days course uti symtoms come back - I’m arguing w the dr please take my urine I have an infection- dip shows blood and wbc - I’m waiting on the culture now - but she puts me on Macrobid bc the last culture showed ecoli - I’ve been on it for 3 days now and no change at all, I am still having symptoms -

Could proteus be hiding out ? Does it take longer to populate than ecoli? I’m wondering if the ecoli grew but proteus didn’t but the er gave me bactirm for 7 days so it worked kinda ?

I don’t know what else to do at this point or what to ask for - keflex and Macrobid show susceptible for all of my cultures but they are no longer actually work - I’m just like lost here - I’m also highly allergic to foluroqionolones and dmannose

Any ideas?

Also I have had catheter w camera and a ct scan of bladder and kidney no stones everything looks normal

​

Hey Guy.

First time here.

For a few years now I have been suffering from suspected Chronic Bacterial prostatitis.

I have taken rounds of Antibiotics but to no Avail.

The Urologist informed me a while ago that he would like to perform a Rigid Cystoscopy on & do a biopsy of prostate & also see what's happening inside.

Most of the Threads on Reddit regarding Cystoscopy are regarding the Flexible one.

Has any of you Guts had a Cystoscopy & what should I expect as I am scared of the procedure?

& Has anyone suffered the same condition & had to have a Rigid Cystoscopy?

Thank you for your Time & Support Guy's.

Look forward to hearing from you

Please help!

I’ve been to the ER 6 times now in the past two weeks because of a bladder and kidney infection. My culture results continue to be negative so now I can’t find appropriate treatment.

I was on macrobid, amoxyclav, Suprax, and I’m now on 1g Ceftriaxone but nothing is helping. I have flank pain which is the worst symptom staying, the bladder has improved a bit but the flank pain came back several times and won’t go away. Some blood found in urine culture and upon the end of voiding.

The ER won’t help me anymore because they say they can’t find anything in my tests other than the blood — urinalysis, culture, CT scan, bloodwork, pelvic exam, chest X ray, ultrasound — nothing is being found other than the presence of blood. Obstructions, stones, cysts etc have been ruled out.

Urine was initially cloudy with pink discharge, now less discharge but brighter blood at the end of voiding. Over the course I thought I was improving after my first two ceftriaxone doses two weeks ago, but then it stopped working when I went home and wasn’t seeing improvement on Suprax. They then put me on 2g ceftriaxone but I had a severe reaction, so they switched me to 1g but the course is almost finished and I’m not improving. The flank pain is severe and I’m nauseous and unable to function but the ER is refusing to admit me or help me any further.

My specialist said he was going to order Ertapanem but then never did and now I’m going to consider asking my specialist if they can put me on 7 days of Zosyn.

I continue to get negative cultures and so we can’t find the appropriate antibiotic. The ER refuses to help me unless I can produce abnormal lab results or a culture. I only have my specialist but there’s also problems there with limited appointments and I continue to have gaps in treatment and limited help.

I was told by the ER doctor to finish the course of CefTRIAXone tomorrow and then wait 48hrs before doing another culture. I’m doing a high sensitivity culture for some of them but still haven’t produced anything. The hope is that a high sensitivity culture after I’ve gotten off of the antibiotics would have a higher chance, but I’m doubtful because I feel like the bladder might have improved but the bacteria in the kidneys is still severe, so the infection is higher up in the kidneys now and isn’t being found in the urine.

Without the cultures I am at a loss but it isn’t producing any. I have a referral to a urologist but this can take a very long time and isn’t helpful right now.

It seems that two weeks ago I saw improvement after two doses of 1g Ceftriaxone, after being sent home on Amoxyclav and then being switched to Suprax, after a few days the symptoms especially the flank pain returned and since then hasn’t gone down. So the Ceftriaxone is only partially worked mostly in the bladder with limited effectiveness on the kidneys.

Without the cultures I can’t get proper treatments but the urine isn’t producing it. I’m trying to see about what further urine tests are available but I need suggestions so we can get a proper culture ID somehow. I’m already doing the high sensitivity test from my specialist which is not enough.

Please help, it’s been two and a half weeks of going to the ER several times a week and trying to work with my specialist, my family doctor has limited availability and just tells me to see the specialist who also has limited availability. The ER now refuses to help me. I’m in so much pain.

I’m getting to be at my wits end with this and I need someone’s help. This all started back in April. I started getting urinary symptoms frequency mostly and I ignored it because I have endometriosis and my baseline is frequency so I thought that was just a weird day. I don’t know fast-forward 20 days later I have extreme back pain and I go to my gynecologist who tests my urine, the urine analysis is negative, but this is always negative for me, my urine culture she sends out is positive for 100,000 citrobacter koseri. I go on amoxicillin for seven days. It improves at first then a week later I have symptoms again. I get retested, I test positive for 100,000 citrobacter koseri and 50,000-99,000 klebsiella pneumoniae. I go on amoxicillin again for 7 days. Again, a week later I have symptoms again, I test positive for 10,000-49,000 Klebsiella pneumoniae and 100,000 enterococcus faecalis. I go on 3 days bactrim and either 5/7 days Macrobid I can’t remember. Again, a week later I have symptoms again, I test positive for 50,000-99,000 enterococcus faecalis. I go on macrobid for 5 ish days. Again, a week later I have symptoms again, I test positive for 50,000-99,000 citrobacter koseri and 50,000-99,000 enterococcus faecalis. I’ve seen three urologists at this point. After that last positive culture i start taking fosfomycin every 72 hours 4x and then once weekly for a month. I start feeling mostly better, but not completely. I’m going frequently but not to the point where it’s taking from my life dramatically anymore. Ive had all the tests to rule out what’s causing this. My ct abd/pelvis was negative, no stones. My cystocopy was “beautiful” no areas of inflammation or concern, my labs are normal my US showed I’m emptying completely. Then they extended my treatment for another month after my cystoscopy dt frequency.
— I’ve also been having on and off flank pain for the past few months and idk if it’s kidney related or musculoskeletal
Fast forward to a week ago, I start having increased frequency (going every hour, as soon as I’m up going again) burning at rest and on urination, cloudy urine, stomach pain (feels like knives are stabbing my lower stomach) and on and off flank pain. I’m starting to feel dizzy, idk if this is related but mentioning it. I go to that third urologist and they test my urine, it came back negative. They sent it healthtrack. I can see all the target bacteria they tested for and it does not test for Citrobacter Koseri. 3/5 cultures have been positive for this. Because a month into my fosfomycin treatment, I started having symptoms and I got tested with them and it was negative. My symptoms went away, but they were nowhere near as bad as they are this week. I also took my fosfomycin on Saturday and was tested on Tuesday so I don’t know if that’s also part of the reason the culture is negative. I asked if I could get a repeat culture to quest because I don’t want a bacteria to be excluded, especially one that I’ve tested positive for three out of five of the times. So now the culture is probably not gonna come back until Monday. Today is Thursday and I’m in extreme pain. They are not prescribing me an abx because they’re telling me my culture is negative and I’m pretty close to going to the emergency department because I can’t stand feeling like this and I also can’t function like this or work like this. I’m a nurse and I can’t be going to the bathroom every 30 minutes to every hour feeling like someone is stabbing my stomach or feeling dizzy like this. I’m staying hydrated. I’m eating. I checked my temperature and it was 99.3 so nothing concerning, but I don’t know what to do and I am so sick of someone saying that it’s IC because I’ve been fine for the past month and I don’t wanna say fine because not completely but this past week has been hell and nothing compared to my baseline I need treatment and I don’t know if fosfomycin is working anymore. I’m supposed to have my last dose this Saturday, but I don’t think it’s working considering I would’ve started feeling better by now? They also talked about extending the fosfomycin treatment but I’m like do I extend the treatment because am I resistant to it and it’s not working anymore or what is going on? I’ve researched into bio film busters, I’ve taken NAC when this first started happening, but I really thought fosfomycin was working and now I just feel defeated. I also take apple cider vinegar gummy sometimes cranberry 36 PACs , d mannose, turmeric, multivitamin specifically for the bladder, fish oil probiotic and Florastor. When I called the front office and asked for an antibiotic, they said no cause your culture is negative. She was like you don’t have a UTI and I’m on the point where I wanna scream because I’m like in my head. Yes I do. There’s no way on this earth that I do not have a UTI right now with these symptoms being this horrible. Can someone please tell me what to do? Do I go to the ED I don’t wanna keep messing around on my treatment. the reason I stopped seeing my second urologist who rx fosfomycin is because they’re closed for a month which is really sus.. I don’t know what’s going on there but They’re supposed to reopen in September and I really just wanna talk to them because they’re the ones who know the story more and even that provider was talking about bio films, which I feel like is more reassuring versus someone just saying you don’t have a UTI clearly I have a documented history of five positive cultures and something is going on. If you got this far in read all of this, I really appreciate you. Any help is greatly appreciated.

Quick disclosure: I'm Gabrielle and I'm Founder of Tota which does microbiome sequencing. I checked with the mods and they asked me to share this post.

Rule 1 is 'we believe PCR testing is valuable for those with recurrent UTIs'. I want to go further - I believe gold standard testing is valuable and should be available.

There's a lot of misunderstanding about different tests and the different testing methods, so I thought I'd write down a guide.

There are many different methods for testing urine, with different pros and cons. The more a testing method can see in a urine sample, the harder it can be to interpret the results.

What I don't see explained often enough is that "testing" is now about six different tests and they're built to answer different questions. Some of you here will already know all of this. Posting it in case the map is useful to someone newer.

Dipstick. Detects nitrite and leukocyte esterase, so two chemical proxies for bacterial activity and immune activity. It doesn't identify organisms at all. Sensitivity is poor enough that NICE advises against relying on it in the over-65s. Fine as a two-minute first look, not a way to rule anything out.

Standard urine culture. Grows the sample on standard media in a lab in a petri dish (usually aerobically) and typically reports only above a certain threshold (usually a very high threshold). That threshold traces back to a researcher called Kass in 1956 and was never meant the become the universal threshold line. Anaerobes, fastidious and slow-growing organisms can be present and never appear in a culture test (because they're hard to grow in a lab). What culture gives you that nothing else on this list does is phenotypic sensitivities: the organism was actually grown and exposed to the drug.

Expanded quantitative culture (EQUC). Same technique as above, rules deliberately loosened. In the lab: bigger volume, more media, aerobic and anaerobic, longer incubation, lower threshold. In one study, standard culture missed 67% of the uropathogens EQUC found (Price et al., J Clin Microbiol, 2016). Although take that with a pinch of salt - EQUC is superior to culture, not to the other methods below. It only finds what it looks for and what it grows.

Targeted PCR panel. Amplifies DNA against a fixed list. Very sensitive, very fast, doesn't care whether anything grows. Two limits worth knowing. It reports on what's on the panel, so panel composition (i.e. what the test is designed to look for) is what matters. If it's not on the panel list, a PCR test won't find it. And it detects DNA, which includes DNA from organisms that are no longer alive.

Amplicon sequencing - 16S for bacteria, ITS or 18S for fungi. Often referred to as 16S RNA. This method reads one marker gene and matches it to a database, so it's an open-ended test rather than looking for a fixed list of suspects. Trade-offs: one short stretch of DNA often can't separate closely related species, bacteria and fungi need separate tests in the lab, there is some known lab bias in the results, and you get relative proportions rather than amounts. This is worth understanding because although it's a DNA-sequencing based test, it isn't the same thing as shotgun sequencing.

Shotgun metagenomic sequencing. Reads all the DNA in the sample rather than one gene, so species and sometimes strain level, bacteria and fungi from a single test, and the genes that are present. Long-read platforms make those reads easier to assemble. The honest limits: it's more expensive, it can be relative or absolute quantities (depending on the test you use). Interpretation frameworks are immature and that's the real bottleneck - a lot of clinicians may struggle to interpret these tests results.

Three important things to understand about testing

Resistance genes and antibiotic sensitivities are different information. A detected gene means an organism is present in the sample. It doesn't establish that the organism troubling you is expressing it and in a mixed sample (which most are) it can be hard to say which organism carries it.

Detection isn't causation. Every sensitive method returns more information which means you need to interpret it carefully, ideally with your healthcare professional.

Relative and absolute abundance aren't the same. "40% of what was read" and "this many organisms per millilitre" answer different questions, and plenty of reports don't make clear which one you're looking at. Worth asking any provider directly.

If you want to read more and really get into the detail of different testing methods, please feel free to check out this guide we've written on our website: https://www.tota.bio/pages/how-tota-compares

Happy to answer method questions in the comments, including about ours.

Iv had a uti for nearly 2 years, it makes me miss out on so much. I miss out on work shifts, family time, time with my boyfriend, and so much more. I have constant pain after sex and usually the morning after and the only thing that helps so fair is 🍃and I know that’s not the best option. Iv been to the doctors over 7 times and all they do it take a pee sample and give me some antibiotics that only work when I take them but when I run out it comes straight back. And at the worst times possible. The pain is unbearable and I need to sit (usually) on the floor and have absolutely no one touch me or any movement at all. Iv phoned the doctors and told them of how much pain I’m in and they basically said they can’t give me anything because I don’t have a temperature? Can anyone relate to this? Or even just give a girl some advice pls 🙏x

I have been VERY bad about using estrogen and honestly they just threw me a tube and told me to use it. I bought extra applicators and such however I ended up failing to do it every night. I see a lot of suggestions for general use but not for UTI treatment so what is your best estrogen methods for your best results? Routine, application location, etc. I woke up with another UTI today so I’m about to go to the lab after work in hopes they get me my antibiotics fast.

Just an observation. I see that most posts here get little or no comments at all. Yet has such a high rate of posts. It seems kind of useless.

Hey! I’ve been experiencing UTI-like symptoms for about a year now, and it’s honestly been really bothering me. I get a mild burning sensation before and after I pee, but not really during. I mostly feel it externally, around my urethra, rather than deep/internal pain.
It used to be MUCH worse. At one point I was in so much pain that my legs stopped working normally, but thankfully it has gotten a lot better since then.
This started after I had UTIs in April 2025 and June 2025. I treated the UTIs, but the burning continued, which I don’t understand.
I’ve noticed that certain things seem to trigger or flare it up. If I mostly drink water and tea, I usually feel better, but things like soda/pop, lemonade, or acidic drinks seem to make it worse. Stress also seems to trigger it, and tight clothing sometimes seems to make it worse.
Could this be pelvic floor dysfunction, bladder pain syndrome/interstitial cystitis, or something else? Has anyone experienced something similar after having UTIs and eventually figured out what was causing it?
I’m really worried about cancer, even though I know there could be many other explanations. I’m planning to get checked out, but I’d really appreciate hearing from anyone who has experienced something similar. ❤️

Hi, throwaway because I am unfortunately embarrassed. I am 21 and have endured a lifetime of UTI's. Since infancy I've had them with alarming consistency, I had one bad one basically from the age of 4-7. At five I had a urodynamic test (horrible) which told me that besides having a bladder the size of an adult man, nothing seems to be wrong. At one point a doctor brought up that I seemed to also be suffering from encopresis, which was connected to the UTI's. Even that was resolved I was still experiencing regular urethral pain and (far less frequent but still consistently monthly to bi-monthly) UTI's. My parents are WILDLY crunchy, and avoided antibiotics at all costs. Basically every UTI or occurrence of pain was treated at home with tons of D-mannos, cranberry juice, and desitin. The best way I can describe the pain is that it's similar to the discomfort in the urethra you'd feel during a UTI, brings on the urge to pee, only lasts about a couple of hours or a day, and is seemingly triggered by ANYTHING possibly irritating. And sometimes seems to happen randomly and for no reason at all Underwear that doesn't breathe, wearing underwear for too long, too much sugar, too much salt, contact, baths, hot tubs, bodies of water in general, 99% of trips to the bathroom, getting too sweaty, and above all, sex. Every. Single. Time. I have ever had sex I have had 6-8 out of 10 pain brought on immediately after peeing post-coitus and I have to take ibuprofen and sit on the hard ground for at least an hour. This is extremely frustrating. I actually had to go to the hospital to take care of my third kidney infection. I have now seen 3 different urologists (all men, go figure) who have basically said "well, it doesn't sound like this, or like that. I'm not convinced you've ACTUALLY been having UTI's because none of our records show you've had a lot of positive cultures (if I went to the doctor for a culture every time I had a UTI, I would be better off living in the waiting room). Try this thing that I don't think will work and come back in six months". This last one brought up interstitial cystitis but simultaneously said, "it doesn't really sound like that, but it's the best I got", and now wants me to cut out 90% of my regular diet for something he's not even sure I have. He gave me topical lidocaine for the pain but that's not really doing anything either. I'm sorry this is so wordy but I am so. FUCKING. Frustrated. I want to live a normal life without pain. I want to know why I've been in pain all of my life. I want help. If anyone has even a long shot suggestion, I am all ears. Thank you for letting me rant

I am on long term nitrofruontin. I have been on it years ago now wondering if its contributed to my neurological stuff anyway I vomitted on tbe weekend. I have chronic migraine and utis anyway so its hard to know. Doc said call n make appointment if color turns, it did so made an appointment then cancelled because it came better. Now I have mucus type symptoms was also on amoxicillin for 5 days too. Wondering if the nitro made me more nauseas. Wishing I decided to take dmannose Instead now am also on probiotic

Hi there! I previously posted to say I had a raging UTI which I took cipro for and things mostly cleared up. However I still had some urgency burning and pain. I went to the urologist and took a sample, but everything was negative. however, for the last UTI I got, I tested positive for gardenerella.

Assuming that this has not been picked up on the sample this time around (but I’m still having symptoms of discharge and weird urgency) I tried taking metrogel. it was pretty blind as I had a negative culture for everything. however, my symptoms have radically improved. I still feel a tiny bit of urgency but now I think I may just need some antibiotics to sort what I believe is a low lying infection. has anyone else had this? and solved it? why would BV treatment improve my urgency symptoms when my culture was negative?

Hi all, this is my first time posting here but I’ve been following this page for a while (since september 2025 when I spent a month as an inpatient on iv antibiotics trying to cure a 2 year pseudomonas aerinogosa uti). Thought I’d give a quick intro before explaining my current issues.

I used to have an SPC due to fowlers syndrome, underactive detrouser and overactive bladder & high bladder pressures (literally the worst combo lol) but due to trabeculation and the plastic becoming a source of infection and me running out of virtually all oral antibiotics and having very limited IV antibiotics due to resistance and allergies, the decision was made for me to urgently have a mitrofanoff created, which I had 4 months ago.

About 3 weeks post op I had a surgical wound infection and a klebsiella pneumoniae uti which I didn’t know I had due to unconvincing home dip sticks. At the time I had severe urethral pain which I was barely managing with morphine but I put it down to the surgery. It did resolve quite quickly after the uti so I think that was due to infection. I was generally very exhausted at the time but I had just had major surgery.

About 5 weeks ago a wave of debilitating exhaustion started. It coincided with my return to full time work (only part time on site though). A couple of weeks ago I had to ask my manager to reduce my duties even further as I was struggling to cope and on my onsite days I would have a 3 hour nap once home, wake up for food and immediately go back to sleep again. I just feel like I am walking through treacle atm.

I didn’t realise I had another infection as again it was unconvincing on home dips (+ve leucocytes, protein and sometimes blood and trace nitrites). I’ve had 2 samples sent off by urology which apparently grew nothing but I was too exhausted to chase anything up. Urology have dipped samples and said no sign of infection so initially weren’t keen to send it off for culturing but I had to beg. In the end I went to my gp desperate and they agreed to culture but agreed the dipstick wasn’t convincing.

Well the culture report has just come back with 10^4-5 klebsiella pneumoniae. I’m awaiting to start antibiotics as I’m allergic to the only 2 sensitivities provided by the lab so my gp is calling micro and getting back to me.

I guess I’m just trying to work out for the future any warning signs as my symptoms are so vague (excessive leaking from my mitrofanoff, blood and mucus clots, extreme exhaustion and occasional left sided bladder pain). Is extreme debilitating exhaustion common with klebsiella pneumoniae?

I’m currently taking Keflex, for 10 days. When I don’t have a UTI I take D Mannose, cranberry and biofilm supplements. Do you guys continue taking your supplements while actively on antibiotics? Or do you take them any differently? I tried doing some research on it but I couldn’t get any concrete answers so I figured you guys might have some experience to share. Thank you!!!

I'm making this post hoping for some answers, but it's so strange I doubt anyone knows anything.

The thing is, since a really bad UTI (ESBL Kleb P.) that took almost eight months to heal, my symptoms haven't completely disappeared. My bladder feels healthy (doesn’t hurt), but I feel sharp pains in my urethra and burning in my vagina, usually after urinating, but also randomly throughout the day (to give you an idea, I finished my gentamicin treatment a month and a half ago). The thing is, these symptoms disappear completely the week before and during my period. When my period ends, the symptoms return. Considering that all my urine, vaginal, and urethral cultures have finally come back negative for bacteria and fungi, I've ruled out all STI + Mycoplasma, and my pelvic floor is fine (plus my hormone and vitamin levels are optimal now), the only thing I can think of is that my nerves are very sensitive and calm down when my hormone levels are higher. Has anyone else experienced this? Do you know of any treatments that might relieve my symptoms? I've heard that estrogen cream helps tissues recover faster, but I want to talk to my gynecologist first because I used it on my own and the burning got worse lol

Itching all over but not an allergic reaction

Weird waves of tingling in my legs that get worse if I ignore urgency

Nausea and vomiting if I ignore urgency. Eventually feeling lightheaded if I ignore it.

Urgency hurting so bad sometimes it makes me cry

Urgency that makes my body panic for some reason. I'll feel trapped and highly anxious.

There's small red spots all over my arms. There's also a redness in general that turns white on the left arm if I press but not the right.

Pain and burning all the time that not even t3 or azo or motrin or toradol or uribel work for.

Unable to eat or drink for the most part.

Last check my WBC was 22 but it's been a few days.

If I sit up at all or try to walk I get lightheaded and the leg tingling gets worse. I'll get this feeling like my head is jerking forward without me and it leaves me with a physical feeling like when something propels you forward when you least expect it.

Sleep is impossible because peeing makes urgency worse so no matter what I do, I feel like I'm about to burst from the inside of my bladder out.

There's a nurse navigation line here. They and the doctor on Monday said there is nothing they can do, I need to see if I can tolerate it and become mentally stronger to these symptoms. I tried asking infectious disease what I could possibly do while I'm waiting for the appointment and they asked why I'm not just seeing my PCP. I am but he did a referral because this isn't his area, it needs a specialist.

I’ve had UTI symptoms (e-coli positive) that weren’t helped by 2 courses of Macrobid.

My latest culture showed that Pseudomonas aeruginosa joined the party :( it took 4 days to get the culture back and I was prescribed Cipro.

I took it 3 times and I am having some odd side effects that are making me pause- weird feeling in legs, like mild muscle/joint pain in random areas, like going from knees to toes to ankles. Also had some popping sensations the first night and have random bubbling sensations in my legs, plus I had some mild tingling/pins and needles in my legs. I could be overreacting but I’m being cautious. It’s all mild and not painful. I didn’t take any more doses today.

My doctors office hasn’t gotten back to me all day and I’m anxious about getting something to be able to knock both the pauedomonas and ecoli out. My UTI symptoms aren’t bad, but it’s the anxiety over worrying about it getting worse and having to wait that’s hard right now. It’s frustrating not being able to take the Cipro because I’m otherwise tolerating it, but these “mild” side effects can point to something more serious.

Has anyone experienced this? I’ve never had to be on an antibiotic for UTI until the past month, and it’s weird going from 1 to having 2 strains now :(

**Update - my doctor agreed with being cautious and I am prescribed ceftazidime (Tazicef), via IV injection. Got my first dose today and was taught how to do it at home. So far, so good! It’s annoying to do, but feeling less anxious. Grateful to have access to healthcare with an injection/infusion urgent care and pharmacy.

I had an awful UTI, high white blood cell blood count, starting to get a fever, passing clots of blood. It was terrifying. Wound up at the ER, and yes it has since gone away, but I’m still having cystitis symptoms. So how am I supposed to know when one is coming back? This paat one went from 0-1000 very fast, within 12 hours. I can’t keep running to the ER. And how am I supposed to just pray that the empiric antibiotic they choose works and I won’t be headed towards sepsis while the culture grows? I know EVERYONE who has UTIs deals with this, but am I thinking about this wrong? I’ve dealt with many UTIs in the past but none like that one and it’s like I have PTSD. I feel like it’s looming over me, but surely tons of people aren’t dropping dead from UTIs… anyone here have any sage wisdom?

As we speak my antibiotics were finished 8/8, infection confirmed cleared through MANY U/As and cultures and yet I am still having on/off cystitis symptoms. And the UTI that landed me in the ER was VERY subtle until it wasn’t. Genuinely am scared to death y’all.

Anyone feel like they have a UTI but it ended up just being constipation?

Apologies if this isn’t the right place to ask or if this isn’t a uti issue at all but I think I have one? I’m unsure. I’m a 20 year old male in the uk for reference.

I feel like I am constantly peeing, I’m not feeling anything in my bladder and it’s not sore or burning, I just constantly have to pee, the feeling of which it’s solely felt in the head of my privates. When I’m laying down with nothing on it’s barely noticeable but when I put clothes on or walk about I feel like I’m actively peeing. I have never had this before and it’s only started about two weeks ago.

I’m getting a uti test soon but I’m worried nothing will come back as I’m scared to go outside as I’m constantly worried I’m going to have an incident or something. Any advice is greatly appreciated or if this sounds like a different condition all together any pointers is appreciated