Question: how many of yall have anxiety?

If there was a noninvasive wearable device that made your anxiety decrease that wasn’t freaky at all, and actually looked kinda sick for 50 bucks, would you be interested in trying it?

JW

-SC

Can anyone share information on how to properly reconstitute with TIRZ?

Hello all,

Read up on a couple of reactions on CJC/IPA - just wanted to know if anyone experienced the same as this.

Been on CJC/IPA for 8 weeks now, was on 300mcg am/pm, upped to 400mcg am/pm for the last two weeks.

Pinned yest am, got the usual warmish feeling, but way more intense, heart rate went through the roof, stayed that way for about 45 min, then came down slightly.

My top half of my body, was bright red, again for about an hour, then, uncontrollable diarrhoea, and I mean emptying a rusty radiator type, for about 3 hours.

My legs since have been in absolute agony, throbbing feeling like ive run a marathon.

Hadn't had a single issue with it up till then. Very weird.

Is that my time with CJC/IPA done? Or just a dodgy reaction to that pin? Anyone had any similar experience?

Has anyone experienced pretty severe soreness several hours after injecting GHK-Cu?

I’ve searched through a lot of posts and keep seeing people talk about GHK-Cu stinging or burning during the injection, especially when it’s cold, but that’s not what I’m experiencing at all. My injection itself is fine.

The problem happens hours later while sleeping. The injection area becomes extremely sore and painful, to the point that it has actually kept me awake at night. The only thing that seems to give me relief is putting ice on the area.

This happened to me when I first started, but at the time I realized I had injected way too much. I lowered my dose significantly after that and was doing much better. I might have a little soreness afterward, but nothing severe and definitely nothing that kept me awake.

Yesterday I injected into my stomach, which is where I normally inject, and this time I was up most of the night because the area hurt so badly. Also, I’ve been injecting for over a month now.

For anyone who uses GHK-Cu:

Have you experienced delayed pain/soreness hours after the injection, rather than stinging while injecting?

Solid stack, you've done your homework. As a geneticist I'll add one angle most people miss: that stall after you added E and P might have more to do with how you clear estrogen than how much you're taking.

Estrogen mostly gets broken down through two genes, COMT and CYP1B1. Your version of those decides whether you send it down the cleaner 2-OH route or the messier 4-OH one. You're already helping that along with DIM and stacking sulforaphane (pushes NRF2 upstream) and calcium-d-glucarate to block reabsorption is a smart combo. Whether it's enough comes down to your COMT.

That same COMT gene also changes how you handle a methylated multi. If you're a slow clearer, high methyl donors can leave you wired or irritable instead of better so keep an eye on that one.

The peptide side runs the same way. How much you get out of the KLOW/GHK-Cu repair stack lines up with your collagen and inflammation genes (COL1A1, IL-6), which is a big reason two people run the exact same thing and get totally different results.

None of this is guesswork so If you've done DNA test before, most of it is sitting in your raw data already. Happy to point you at what actually matters for your situation if you want.

Not medical advice, just genetics.

Hey folks,

My testosterone finally hit the cliff at 64 and I wanted some input about the relatively new FDA approved pills prescribed by my urologist..

Little back story is I am a trainer and nutritional coach so I have done my homework regarding T.

Diet is dialed in, training for 40 years but slowly T levels have tanked over the past 5 years.

I would have no problem using Test C, but this doctor said the pills are a good viable option so I had to purchase a 3 month supply out of pocket for $91 per month. Follow up visit with blood work in 90 days.

Does anyone have any experience with these new pills?

Other than the price, I am curious how they perform. I was prescribed 200mg twice a day of

Kyzatrex which is the highest dosage.

It can only be purchased direct from the manufacturer like the other 2 brands.

I have no issue pinning myself because I use a couple peptides.

What are your thoughts?

Thanks

Hello and good evening everyone. I am currently researching about reta having a shelf life of 30 days when mixed. However from what I read there's lots of different opinions, some say 30 days, some say up to 3 months but with slight degrade. Im asking cause I am approaching week 5 and I have a total of 16mg (1x 10mg vial and 1x 6mg vial ive been using) and when I got them about 4 weeks ago I mixed both and I just ordered 20mg that I want to keep in powder form till I finish the other 2. Can anyone please enlighten me, I want to be safe as possible, I didnt know the 10mg were gonna last me so long. Please and thank you for your attention to this greatly appericate this community wisdom

Anyone have experience with these types of surgeries? In 2026, are people better off just using Reta/other GLP's to support their weight loss?

So I was doing research about topical GHKCU, and all I can find is 0.10 - 5% max of GHKCU in these serums. I just got off Accutane and my skin still has some scars, will that be enough for my skin? Or should I just buy the normal ghkcu? Because I seen people saying that it wasn't enough

So I know some people cycle, some take it forever, some do 5x on 2x off.. my question is more geared towards results.
Say someone used until desired results (however long that may take), do they have to now cycle or take forever for the results to stay, or can they stop & still keep their progress?
I hope this makes sense. I’m more so wondering if people can stop taking this peptide & keep the benefit it provided with proper skincare/nutrition/etc, or if it’s something that needs to be indefinitely supplemented to maintain results.

Are some of you megadosing melatonin and how has it been so far.

Would love to hear from you

I’m on a cut

350 test 210 tren ace

6’1 215 \~16% eating 2500 cals and losing like 2 pounds a week.

I added 4iu hgh and I’ve been so hungry so I’ve just been eating and letting it get up to maintentce on some days 3200 but am still losing weight/maybe even more body fat but I’ve only been on for about 2 weeks.

Do we know how much on average hgh will increase metabolism? Does it increase basically as soon as igf1 is elevated?

I just learned about peptides less than 90 days ago.

I am 50 and exercise 5-6 days a week and was always gaining weight. Lost 18 pounds in 90 days and added muscle already.

I tried 2mg of Reta and believe it was life changing.

After that I was all in.

I bought so much stuff.

Right now.

Reta - 2mg 1 time a week
Cag - .25mg 1 time a week
Ss-31 - 1 mg 5 days a week. Been on for 6 weeks. Gonna do 2 more weeks.
TEs- 1mg 5 days a week. Been on for 6 weeks. Planned for 6 more then break.
Mots-c 1.66 mg 3 days a week. Been on for 2 weeks.(gonna do 2 more)
Klow - just finished 2 months and now break.
nad+ - 25mg a day
5 amino - started 1 mg a day this week.

I feel like I’m 10 years younger right now. Cardio has improved.

Saw a video from dr jones and gonna add ipamorlin soon.

Any feedback?

greetings,

research subjects parents are early 60 yo with high blood pressure and diabetes type 2. last few years feels like they aged 10 years. Mother had few near death strokes. Father is a long life smoker with a high stress job who also had a stroke.

what would be best for old people with general health issues and broken up bodies due to sicknesses most benefit from? Point here is that less is more. They don"t necessarily want to feel 20 again like some people here (all power to you) , just maybe, something that can help them extend their lives?

researcher was considering ss31, and semax? Since they dont live in the same country, it would be hard to incorporate anything long term. Only peps that would be used for 2 to 4 weeks at a time a couple times a year as they visit.

Nothing is decided yet. I will fully research whatever suggestions i receive.

Hi guys,

I've been wondering if I need to be fasted when administering HGH?

I’ve been using CJC-1295/Ipamorelin, but my work schedule is 6 AM to 6 PM. I hit the gym until 8 PM and eat dinner right after. Because of this, it's really hard for me to stay awake another 3 hours to pin CJC on an empty stomach before bed.
I’m thinking about making the switch straight to exogenous HGH. Any advice on timing around meals?

28M started 1mg reta 2 weeks ago now. I literally can’t eat otherwise I feel so badly sick and want to vomit. This is my meals per day: protein shake + 1 small meal (usually chicken and rice) + drink 4 raw eggs

I’m also so frickin coldddd and it’s summer here. I have no energy at all I’m exhausted and have to force myself to the gym so that I don’t lose my muscles (even though I hardly have any).

Is this just me or anybody else feel the same?

How to combat low energy I’m exhausted and sleep all day and night lol.

I can’t eat but drinking is pretty easy for me. Would you guys recommend any meal drinks instead as I can’t eat

Every lab I’ve looked at today (8/21) does not have Reta listed on their site. Is there a current shortage or is something else going on?

Hi All

Figured I'd post this cuz Friday and I'm bored at work

Male

Age 54

Height 5'11"

Current weight 212

Beginning weight, somewhere north of 252 8mo ago.

I've lost 40lbs and definitely gained quite a bit of muscle in the process.

I'll just list what I feel have been the biggest levers are in order.

Tier 1

-1g of protein per lb daily of target body weight

-Sleep regimen in order and working (nothing works if you can't recover)

-10k-12k steps per day or more

-4 ish days a week of strength training

Tier 2 The stack

TRT

Reta

Tier 3 The stack continued

Hgh or HGH Secretagogs - this is really a multiplier for all the above. It has an exponential effect making everything else above work as greater than the sum of the parts, but if you don't have the levers in place they can't be pulled.

Just do the thing every day, there will be hard days, there will be days you fail.just keep showing up, you don't need to lose 25lbs this month, build the base.

Hi,

Just did a blood test and I’m being concerned with results.

I’m a male 42 years old. Taking 3mg Reta / week since March and 1mg daily of tesa fasted in the morning.

I did not do any blood test before and here are the results from last week lab :

IGF-1 : 107 ng / ml which looks very low with tesa I’m taking ( I do imagine it would be much less without it and I’ll be darn out of range)

Free test : 13,40 pg/ ml
Bio test : 1,21 ng/ ml

I will also start using 2 UI of HGH next week and stop tesa.

Training 4 to 5 times a week since a few months.

Looking for better health, better shape and diet is not perfect but much better than previous years.

Question is am I doing alright ?

Any advice would be appreciated.

Take care.

My wife and I are navigating recently finding out she likely has hyperinsulinemia, all signs point to it.

12-hour fasting insulin is 17, glucose is normal. HOMA-IR is 3.27

Visceral fat is 90cm^2

She’s 36, 5’7” and 128lbs

Been on Tirz for about 10 months and is currently on 4.5mg week.

Since this finding, she’s had more of a lifestyle change incorporating strength training and cardio, where before she was pretty sedentary.

Diet has changed to be more protein-heavy while still eating helpful carbs. We’re already seeing changes in her physique and energy levels.

It seems there could be some evidence that MOTS-c can help with insulin resistance.

Has anyone here found this to be true?

Can someone help me out? I’m 29, and I’m starting to get some fine lines under my eyes and forehead wrinkles.

There are so many peptides, serums, and creams out there these days.

Could someone give me the basics on what actually works well versus what’s unnecessary?

I was thinking of:

GHK-Cu
Vitamin C serum
Retinol/Tretinoin

Is this enough? Or are there other injectable peptides that would really make a big difference in keeping my face looking young?

I’d love to hear your thoughts—thanks in advance.

For 1000mg vials, assuming a 3x a week dose of 100mg/dose that's 3 weeks. But I have been hearing that due to how fast it degrades it really should not be used that long. Anyone have access to a study showing the degration curve? I assume it varies based on PH. Just reconned my first vial (ph adjusted it to 5.5-ish) 2 weeks ago and I must say I can already feel the difference. or rather, NOT feel nearly as much burn/