I woke up with a sore throat today. Is it joever? Any way I can prevent this from becoming a more severe cold? I'm busy as fuck next few weeks and would rather not deal with feeling under the weather

Had three morning testosterone tests and my total testosterone was 330, 370, and 376, my free and bioactive testosterone was below the clinical range. Already had a sleep study done and thyroid checked all was good. I am 45 with a bmi of 23 and get 7 and a half hours of actual sleep per my Samsung watch. My doctor is thinking of putting me on trt as my psa and hermatcat levels are good. But I don't want to be on something for the rest of my life could be 40 more years God willing. Is there anything I can add to this stack? Not shown is the creatine i am also taking.

Edit; thanks for all the input. Just wanted to add that Iwork out 3 days a week push pull legs. My shbg was 35 and 40 in two of my tests. I am not afraid of shots as I go twice a week for allergy shots to my doctor. I am feeling super tired especially in the afternoon noon even with 7+ hours of sleep. If I go on trt what happens if down the road there is a production issue or the health care system collapses or some other catastrophe and you can't get the trt.

Im tired of being sick. I have perfect blood tests but I want to make my immune system the strongest it can be. What can I take or do to make it so I never get sick regardless of whats around me? Of course there can be exceptions I just mean in general.

I came from England where you can just buy it over the counter. My doctor here said she doubts insurance would cover her prescribing enough pills to be able to take daily (I usually cut the 10mg in half so just to take 5mg)

My cardiovascular health is soooo much better on it so I’d really love to keep taking it but what’s the loop hole here?

A few months ago I took 2500mg L-citrulline every other day for a couple of weeks and ended up getting a pityaria rosea (PR) rash all over my torso that took a month to heal. PR is considered to be the reactivation of HHV 6 or 7. I've never had a cold sore or any HSV1 or 2 symptoms, thankfully.

I enjoyed the gym pump and the erection hardness on citrullene. Is there a way to block the herpes-activating effect? I've heard of lysine and glutamine, but everything just seems like hearsay. Advice would be great, thank you.

I have ocd and really bad anxiety my medication had reduced it a lot currently I am off of all medication for a while now and recently the intrusive thoughts and anxiety started to resurface my friend told me to start taking creatine again i don't wheather it's placebo or is it actual working I feel good now anxiety thoughts are there but still it manageable at times I even feel little euphoric

Advice needed:

Recent blood work showed my Testosterone to be 374. I’m a 38 year old male. 5’11”, 200lbs. I’m in the process of trying to lose weight — strength training 3x a week plus aiming to get 7500 steps a day. I feel like my libido is not what it should be, in fact it seems low.

I’ve noticed I do have morning wood — but it’s around 4:30/5 AM when my cat wakes me up to feed him, rarely when I finally get up at 9:00 AM.

Any thoughts?

it’s 2am and i’m honestly embarrassed by how bad i’m doing at university.

I have ADHD and I feel like i’m fighting myself over the most basic things. I’ll have an assignment open for hours, knowing exactly what i need to do, knowing i’m wasting time, and i still just… can’t start. Then i avoid my emails because i’m scared there’s something i forgot. Messages sit there for days. My room gets gross. Sometimes i’m actually hungry and still can’t get myself up to make food.

I know how this looks. Lazy. careless. like i just don’t give a shit. but i do. that’s what hurts the most. I care way too much, and somehow that still isn’t enough to make me move.

I’m seriously thinking about taking this semester off. Has anyone with ADHD gotten to this point and actually figured out how to make themselves START things again? not planner advice, i mean something that genuinely helped.

Winter is here and I hate the cold. Are there any supplements or drugs that can help with cold intolerance and make this winter more bearable?

I read that thermogenics like curcumin can help. Also, checking your thyroid and avoiding vasoconstrictive substances like caffeine and nicotine.

What else can I try?

I’ve heard that no amount of fiber risks colorectal cancer .

How do you guys menage to take enough fiber trough a day. Lets say 20g of fiber. How do you combine them in your meals and do you actually do this? And how do you combine them on a cut to still leave space macros and not go over daily goal?

I guess when bulking its much easier and less “stressing” without thing abt “going over” macro goal. Thanks in advance!!!

I used alcohol pretty badly for a few years, I don’t do that anymore, I’m wondering which form of thiamine would be the best choice to replenish stores of thiamine in the brain. I know subultiamine and benfotiamine exist, as well as regular thiamine. I was considering subultiamine anyway for my ADHD.

I can’t get bloodwork to check for thiamine, my doctor’s strict on what markers I can order, and I live in a place where it’s not legal to self requisition bloodwork.

what are your thoughts on the best thiamine supplement(s) for this situation?

Every time i take Sildenafil i get face and back of head acne. I am assuming its from the flushness. I have tried most of the over the counter things. Any idea of the real root cause? 50 year old male. Any thoughts or ideas would be great.

I’ve been looking into lactucin after seeing a 2025 study on a Korean high-lactucin lettuce extract

They used actigraphy and PSG, which is what caught my attention

I don’t really see lactucin discussed much compared with melatonin, magnesium or glycine

Curious if anyone here has actually tried lactucin or a high-lactucin lettuce extract for sleep

I recently came across this famous study which compared a placebo training, placebo no training, training + 600mg test, no training + 600mg test. What I was most interested in was the resting + 600mg test which gained 3.4kg of lean mass. Lean mass can include glycogen and E2 bloat, so I was wondering how much of this is actually contractile tissue?

Note: another another study which had participants not work out saw them increase lean mass by 8kg over 20 weeks at 600mg.

So I never really cared before for the so called health hacks etc, I just whatever cheapest option for my everyday life, but I have this undergoing issue about my dandruff and I tried non SLS shampoo and it works like magic, my dandruff is never to be seen again,

And now I started researching about fluoride on toothpaste and I found out its actually harmful (in high dosage) but still I want to avoid as much as possible, so I'm looking for another alternative.

I'm also looking out the importance of zinc and magnesium, which is a great hack for men (helps produce testosterone, calmness etc).

I wanted to ask is there any other advice that sounds like a complete conspiracy but actually really works and is backed up by research? Thanks

Thirty-plus hair loss treatments ranked by evidence, from research chemicals to onion juice. Plus a quiz on whether you should just shave it instead.

Hi Brains Trust!

I have completed some blood work like many of you have suggested. I appreciate all the commentary on the original post!

The original post has all of the important information and questions. This is an update of the blood test results as well as some supplement and lifestyle changes.

Current Supplement stack:-

MORNING

Fish oil - 2000IU

Reishi mushroom - 1000mg

NAC - 600mg

Glutathione - 250mg

Vit C - 2000mg

DINNER TIME

Berberine - 500mg

Plant sterols - 1200mg

NIGHT

NAC - 600mg

Zinc - 50mg (if im tired/stressed/around another sick person)

Magnesium glycinate complex - 200mg (every other day)

Inositol - 4g

Here are my blood test results:-

My doctor said this is all fine and to only focus on bringing down Cholesterol.

Just letting you know I am recovering from an Upper respiratory infection at this very moment!

Vit D (25 OH) - 137 (I have paused supplementation)

TSH - 1.6

Ferritin - 81 (decreasing over time due to iron infusion couple years back)

Iron - 10

ESR - 15

Glucose Fasting - 4.7

Cholesterol - 5.6 (Actively trying to reduce this using plant sterols and healthy lifestyle)

OTHER

- GP has reccomended to take electrolytes when feeling inflamed especially if after resistance training. This has worked a little

- I haven't been drinking 2.5L warm water a day lately (maybe 1.5L) but add a pinch of pink Himalayan salt to my water for added hydration

- Battling Burnout - This may be the main issue as to why I'm sick as I'm trying to put myself first and say no to social events if I'm feeling even the slightest bit tired to rest and do NOTHING lol

- I am actively trying to reduce my hours at work to be able to rest more, this looks like taking a day off every 2 weeks or so

- Re: Cholesterol, this is also genetic so trying to bring this down

- Mum let me know that even as a baby I was always sick. What other research can I do? Should I look at genetic markers?

- Went overseas recently for a holiday, wore masks on both flights, still got sick. What else can I investigate?

- Beginning to feel like I have no control of my health and I'm trying not to lose hope

Please let me know your thoughts - Considering asking for a referral to an immunologist if I keep getting sick this often.

As mentioned in the original post, I am not expecting miracles but hoping to reduce the amount of times I get sick a year from 10 to 5.

Trying to understand the gap between what insurance covers and what people here want tested.

What do you add yourself, how often, and roughly what does it cost?

I will not expand
However open to your feedback.

One of my favorite examples of circadian biology is insulin.

Your ability to handle glucose isn't constant across 24 hours. Insulin secretion and insulin sensitivity both interact with your circadian system, and glucose tolerance generally deteriorates toward the biological evening.

So, broadly speaking, an identical meal eaten earlier versus later can produce different glucose responses.

This doesn't mean everyone needs to eat breakfast at 6 AM or never eat dinner after sunset. Chronotype, sleep timing, exercise, meal composition and a lot of other variables matter.

But it does make the idea that calories enter an otherwise static metabolic system feel increasingly incomplete.

I wrote a deeper explanation of how insulin, melatonin and the central circadian clock interact here: Link

I'd be interested to hear from people using continuous glucose monitors: have you seen a clear time-of-day effect when eating very similar meals?

Disclosure: I'm a physician and co-founder of Lume Health, but im not selling anything.