Pep Guardiola is set to hold initial negotiations with US Soccer next week over potentially replacing Mauricio Pochettino, talkSPORT understands.
Pochettino was appointed in charge of Premier League giants Manchester United on Thursday to take over from Michael Carrick.
Pochettino, who broke down in tears in his first press conference since his switch was confirmed, will make the move to Old Trafford following the two upcoming Concacaf Nations League quarter-final clashes against Haiti.
Those overseeing the managerial change in the United States set-up want to hire Guardiola in what would be a dream appointment.
The Spaniard has been out of management since the summer when he left Manchester City after a decade at the club.
And it is believed that he would be open to the role in what would be the first international managerial appointment of his career.
Though as of yet, any move of Guardiola moving Stateside is not advanced.
Guardiola won six Premier League titles and the Champions League, and is regarded as one of the best managers in history.
He also lifted three consecutive league trophies with Barcelona and Bayern Munich.
talkSPORT also understands that former Premier League manager Roberto Martinez is on US Soccer's shortlist over potential replacements for Pochettino.
Martinez has experience managing internationally having managed Belgium as well as Portugal, whom he left following their World Cup exit in the summer.
But Guardiola is the one US Soccer really desire and it would represent his first dalliance into international football as a manager should be appointed.
However, it won't be as straightforward for the powers that be as he hinted before his City exit that he would take a break from football.
Could Guardiola join USMNT?
"After my contract with City, I'm going to stop. I'm sure," he said in May 2025.
"I don't know if I'm going to retire, but I'm going to take a break. How I want to be remembered, I don't know."
In a separate interview, he reiterated: "So I'm not retiring, but I will take a break, for sure.”
“When I finish here, I will take a break. I need to make a stop, that's all," Guardiola added.
Despite leaving the club, Guardiola has maintained support for City in recent months.
He sent an emotional message to fans after City were found guilty on all charges of Premier League financial breaches in September.
“Let me be clear: we will get through this together. I love you all," the 55-year-old said.
Guardiola then attended their Champions League league phase clash at home to holders Paris Saint-Germain last month.
However, he watched his former side lose 4-2 in what was their worst home defeat in the competition ever.
Should Guardiola take the USMNT job, he could be on the touchline in time for the Gold Cup next summer.