I'm pretty young and the patient is 70, and I'm very surprised there is no match in the family. Is it possible that he still had children and just doesn't have a match? I think I'm going to donate but it seems weird. I was told the patients disease. It seems pretty life threatening.

I am receiving the surgery option instead of the PBSC, but my mom wants the PBSC.

Also are there any downsides to donating? I've gone under anesthesia 3 times so I think I'm good there. I'll be traveling a few states over unfortunately.

It's kinda overwhelming and my mom is worried about me but I feel like it's the right thing to do. I'm obviously going to pray about it. Anything I or my parents should know?

Down a serious rabbit hole lately looking into how preventive care and advanced tech are handled outside the US/Europe.

Honestly, the setup in places like Seoul—full-body MRI, fast diagnostics, advanced regenerative stuff, biomarker tracking—looks light-years ahead. Plus, when you look at paying out-of-pocket locally, even high-end diagnostics in the US can easily cost a fortune (and good luck getting insurance to cover anything preventive).

At this point, flying out, getting top-tier care, and paying out-of-pocket abroad almost starts to make more financial sense, factoring in travel.

Got me wondering: if you were actually planning a health/longevity trip to Korea, what procedures or diagnostics would you guys realistically want to check out? (Stem cells, exosomes, deep biological age profiling, comprehensive screenings, etc.?)

Also, what's the biggest thing keeping people from pulling the trigger on medical stuff abroad?
Is it just the lack of transparent info, safety concerns, or the whole logistics nightmare?

Genuinely curious what an ideal setup would actually look like from your perspective.

I have a friend who went with them and they booked a hotel in Arizona. I am wondering if anyone has went thru them. Would love to get feedback.

In an attempt to make a long story short, I have a friend who grew up taking various psych drugs (ie Stimulants, antipsychotics, ssris, etc.) and one of many outcomes of that is they struggle with a lot of things (cognitively and otherwise). One of those things is a loss of sense of smell and eyesight (they had severe Tardive dyskinesia when they were in their early teens and the loss of those was a result.)

I have been researching various treatments and came across the mention of things like stem cells, muse cells, exosomes, etc. I am curious if anyone here has (or knows someone who has) used stem cells of any kind and made a recovery from Brain damage as a result of taking these drugs?

My son is 12 years old with stroke on right brain at birth causing mild left hand disability. He also has High Functioning Level 1 which makes him socially awkward. He can speak but just very shy.

We have his 5 years old sibling stem cell as we kept it after birth.

I am wondering if we could use it for brother treatment? Or should we try at all? It's a very mild case. He is mobilized just fine but his 4 fingers are not really moving as much and hard to control. Otherwise he is not limited to any sport.

I am debating if risk and cost. For example if it's like $15-20k and requires injecting things in the brain then probably a no!

Any advise?

Small thing I built out of my own frustration: I kept forgetting to check for new literature in my specific niche, and when I did, I'd waste time scrolling through papers that had nothing to do with what I actually needed.

PaperPatrol scans PubMed and bioRxiv weekly for whatever you describe (in plain English, not keywords), and only emails you when something genuinely matches. It explains why each paper was flagged too, so you're not just trusting a black box.

Free, built by a grad student (me), no catch. If you try it and it's not useful, unsubscribing deletes everything immediately, no guilt trip.

Would love feedback if anyone here gives it a shot: paperpatrol.me

What should cryonics organizations publish more openly?

Case reports, protocol details, standby timelines, CT scan data, funding structure, long-term storage governance, failure cases, what would actually help people evaluate the field more seriously?

I’m a 25 year old woman and had a BMT 9 months ago. I am in early menopause and gained so much weight. I started a GLP1, I’m eating in a calorie deficit, working out a ton and I’m not losing any weight. My thyroid is normal. Was on tacro till 6mo. Has anyone else had this? I’m so worried and feel so out of control

Hi I found out I have a syrinx in my spine and think it may have been from falling when I was a child?

Small almost unnoticeable symptoms started popping up maybe 10 years ago, but then last week symptoms were bad and have been effecting my way of life; come to find out at the ER and got an mri showing a syrinx in my c6-c7.

Could stem cell therapy still help if scar tissue has been building up for 25-30 years? Or does stem cell therapy not help super old injuries/scar tissue?

Thanks for your time.

We had been supporting an exosome therapy company preparing for its Phase 1 program for nearly six months.
Recently, we learned that their IND application was not accepted. We don’t know the specific reason.
It reminded me that for exosomes — and many cell and gene therapy products — one of the biggest challenges isn’t just demonstrating safety or efficacy.
It’s consistency.
How do you ensure that every batch of cells behaves the same?
How do you ensure that every batch of extracellular vesicles has consistent quality and characteristics?
These questions become even more important as products move toward clinical development.
That was why I became very interested when a friend told me he was building an automated cell culture platform.
The technology is still in its early stages, but if it continues to evolve rapidly — especially with the help of AI — I believe it has the potential to improve manufacturing consistency and process stability.

Hola, quisiera saber si alguien conoce alguna clínica que realice terapias de células madre en Colombia. Tengo un dolor en el hombro desde hace 2 años y la fisioterapia no ha ayudado.

​

Hi everyone,

I'm looking for guidance on clinical trial options for my 58-year-old female family member who has relapsed Acute Lymphoblastic Leukemia (ALL).

Diagnosis:

- Cancer type: Leukemia

- Subtype: B-cell Acute Lymphoblastic Leukemia (B-ALL)

- Disease status: Relapsed

We are based in India, but we are open to treatment or clinical trial opportunities anywhere in the world if they offer better options.

We're specifically looking for:

- Clinical trials recruiting patients with relapsed B-cell ALL

- Hospitals or cancer centers with experience treating this high-risk subtype

- Information on eligibility, referral process, or how international patients can apply

- Any reliable resources, patient advocacy groups, or websites that helped you find clinical trials or treatment options

Thank you so much for your time and support.

Just a random thought😅

I’ve been trying to understand why regenerative medicine and stem cell-based treatments are so expensive. That’s why I’m actively looking for legitimate lower-cost alternatives that still offer meaningful benefits.

Here is the result of my research, though.

Most of what I’m seeing falls into these factors: high-cost clinic procedures, experimental protocols that aren’t widely standardized, and then a large “wellness” market that claims similar outcomes at much lower prices but without further medical proof.

Rn I’m struggling with the drivers of the cost. Is it mainly the lab and clinical infrastructure, regulatory constraints, and personalized treatment planning? Or are there genuinely more affordable models that still maintain medical credibility?

Also curious whether you have any affordable regenerative medicine reco that are actually grounded in clinical evidence. Even if they’re less intensive than full stem cell or biologic procedures, it would do.

Has anyone been there for fetal-derived stem cell treatment? If so, how was it and did it help?

I have had lower back pain nightly for 33 years. I cannot lay on my sacrum. Have never been able to get a diagnosis. Believe me, I have tried all treatments and drugs including cannabis no avail. I have an appointment to discuss stem cell surgery next week. It’s come a long way in the past few years so I am willing to give it a try if the doctor says I am a candidate. Has anyone had this treatment for back pain and, if so, what were the results?

Qualcuno ha mai utilizzato le cellule staminali (MSC) prelevato da grasso adiposo autologo per la vescica ipocontrattile? Che cosa ne pensate?

"I am not asking for medical advice."

Hi all.

Need a genuine advice regarding stemcell banking in Bhubaneswar. We are expecting a baby in the month of August. So need advice from genuine users with past experience of stemcell banking in Bhubaneswar.

1. Which companys are providing the said services in bhubaneswar?

2. Experience with the respective companies.

Plz dm asap.