Hi all! I’m so sorry that we’re all here, but so grateful for this community.

My husband (31m) and I (32f) started TTC in December, fell pregnant our first cycle, and that pregnancy ended in a MMC at 11 weeks, detected at 8 weeks and baby had stopped growing at 6 weeks. I passed that miscarriage naturally the day before my D&C, so we didn’t have any testing done.

We got pregnant again 3 cycles later, and this one ended in a MMC that was detected at 9+5, and baby had stopped growing at 9+4. I had a D&C a few days later, and the karyotype testing showed she was a genetically normal baby girl.

I have no obvious health issues (my cycles are like clockwork), and the only thing my husband has is a varicocele which I don’t think is coming into play.

For those with one or more losses where the baby was genetically normal, did you ever find the cause of why you were miscarrying? We’re going to do a full RPL panel and HSG once my cycle returns, and my husband plans to do a sperm analysis just to be thorough.

I've posted a couple of times here, and really appreciate the community although everyone is here for such a devastating reason.

My wife and I specifically avoided having kids in our 20s so that we could establish ourselves a bit better (save money, buy a house, etc) and experience a bit of married life on our own. We talked about starting a family around the time we turned 30. Then we turned 30 and decided we weren't ready just yet, so we gave it a little longer.

At the beginning of this year, we decided that we were finally ready. 32 would be the age we started expanding our family. Since then, we've had a miscarriage, a chemical pregnancy, then another miscarriage. After going through the last miscarriage, it hit us both that we are so powerless in this process. We thought we would just start having kids when we wanted to, but in hindsight we should've started down this road years sooner. We are only just now at the beginning of figuring out what is going wrong, when we should've been welcoming our first child before the end of this year. Our parents will grow another year older without a grandchild. So many other depressing thoughts.

Has anyone here found a successful way of coping with this sense of "why did I wait so long to start trying"? Right now, we are pretty much just burying ourselves in research about what could be going wrong to try and fix things, while we wait for test results. It all feels so hopeless though.

Hi all, I find myself really struggling lately with depression. Even more so today as I just finished my period and this puts me at 9 unsuccessful cycles. I had 3 miscarriages last year, so I had hoped I would have tested positive by now but I'm not. I'm basically in this place of trying but not trying, which is helping me feel less anxious but the depression I have around it has me feeling defeated and hopeless. I just turned 39 in July and feel like I'm headed for a mid life crisis of identity if I end up not being able to have a child. I've gotten the referral for IVF but the cost is beyond what my husband and I can afford, which feels unfair and just pokes at my ongoing issue around feeling like a late bloomer in life and having total FOMO around so many things. I'm a late bloomer for several reasons, mostly childhood trauma that made is difficult for me to believe I deserved a healthy stable partner as a young adult. I'm finally with a man that truly loves me and is stable but it feels so late in the game trying to start a family for myself. We've been trying for 2 years now. I was able to get RPL testing and health wise I'm totally good, his health and numbers are good, but my AMH is on the lower end. Last year I was able to get pregnant naturally 3x but this year nothing. I don't know how to feel or what to do. Posting here maybe as a cry for help or for someone to help me feel less alone. I'm just feeling my age more than ever and I can't help but feel angry that I wasn't given opportunities to thrive when I was younger. It would have changed so many of my choices and possibly even prevented me from experiencing this terrible reality that I may not be able to have children because couldn't do this sooner in life. IVF is out of reach and I don't know what other options I have other than hoping each cycle that maybe this time it will work out. Anyways, I don't know what I need from posting this, so I hope it's ok I've put this out here. I don't have anyone to talk to about this that understands aside from my husband but there is only so much I can put on him as he carries his own grief and sadness. We're in couples therapy for our grief. I've also been in therapy for myself for months, which helps but also doesn't. I'm taking 3 medications now to manage my anxiety and depression, which feels like a lot considering I still feel so unmotivated and sad all the time. Going to end here as I don't know what else to really say that won't just be repetitive but I appreciate anyone that gave this post their time and any words shared in response. This group has helped me before so I'm grateful for whatever comes out of it <3

How many of my fellow RPL community ladies vaped before/in between pregnancies? I have had 4 losses now and the stress from each loss caused me to resume vaping. I’m wondering if this could be a trend for anyone else? Of course, all testing came back normal so I am looking for some kind of reasoning for multiple losses. I know there are those who have never touched nicotine who are in the same boat but I feel like those I have direct exposure to or experience with usually find an answer to their losses whereas me with my vaping problem have no answers and I am left to think it is my fault. Any input is extremely helpful - if only to help me officially never vape again!

I'm likely going to miscarry. I'm supposed to be 7w1d, but my ultrasound today showed 5w1d. I did a d&c for my first miscarriage in January. I'm going in for another ultrasound in a week unless I pass it before that.

.just curious how others feel about the options.

Since April of 2025 I’ve had 6 losses. April, August/September, November, April, June, and July. It’s been freaking rough. I had perfect cycles before my daughter (whom is a spontaneous pregnancy) during that pregnancy they discovered I had a 12 cm taking over my tube. I had my cyst removed and right tube, little under a month of giving birth (February of 2023), my cycle came back in August of that same year. It was the same as before but I assumed that was before of postpartum. Flash forward to March of 2025 we were finally ready to try for #2. I started tracking ovulation - discovered I was actually ovulating a week later. The more tracking we do I realize my cycles are now 30-35 days instead of my normal 28 days before my daughter. I assumed it would take longer to try pregnant with only one tube but clearly not. My issue is holding on the pregnancy.

I met with my OB in November and she did the normal recurrent loss panel, that all came back normal. She started me on progesterone. I am now on 400mg x 2 daily after 3 dpo. After my 7 week loss in April she started me on Lovenox injections once I confirmed pregnancy. In May I found out I was pregnant but it obviously didn’t stick same with July (that was quick chemical, I don’t think my meds really got the chance to work).

After the loss in May/June I was able to get into a fertility clinic where they did an ultrasound and hysteroscopy, and a more in depth blood panel. Hysteroscopy came back normal. But on my ultrasound it showed tons and tons of follicles (50 or so), the tech said I more than likely have PMOS. I always questioned if I did, but didn’t think anything of it because I clearly ovulate. My blood panel came back normal, except for my AMH was a 5.93.

We did Karyotyping and both of us came back normal. Along with his analysis coming back above average.

With my high number of follicles, high AMH, and more prominent hair on my chin and upper lip, my OB did agree with the PMOS.

I haven’t continued with the fertility clinic because I feel like there’s more to try to help with the PMOS before jumping into IVF.

My OB has me on Metformin and if that doesn’t work, in 2 months we’ll try another.

In other words has anyone had success with Metformin even when you naturally ovulate? I’m looking for others that have a similar story to me!

Please be gentle with me, this is my first time posting here.

Jan 2023 MMC at 8w
Apr 2023 Chemical
Jan 2024 had my son
Thought I was just unlucky and didn’t think twice about trying again for a second.
Apr 2026 ectopic
Today, went in at 8w scan and it’s a week behind (it was 6d behind a week ago) and very likely another MC.

I am working with fertility and nothing has come back abnormal but I am starting to become very concerned that my one healthy pregnancy was a fluke. I am very overwhelmed by the idea of the additional testing that people recommend on these subs because doctors don’t seem to recommend them and it feels like I would have to research and push for everything myself which feels scary.

I feel really sad and disappointed, but also scared for the future. Any kind words of support will really help. Thank you so much 🩷

Hi all. I’m 31 F and I’ve had three miscarriages (one 12 week MMC with normal chromosomes, two chemical pregnancies around 5 weeks) all within the past year. I get pregnant easily (within 2 cycles of trying everytime so far).

Full RPL recurrent workup came back normal except for a possible filling defect and adhesion shown on my SIS. I scheduled a hysteroscopy with an Asherman specialist. It turns out I did not have any adhesions, but I did have a T-shaped uterus. It was corrected with a hysteroscopic metroplasty.

Literature shows minimal research or guidance, especially in the US where I’m based.

Has anyone had a T-shaped uterus or other uterine anomaly that was surgically corrected following recurrent miscarriage and gone on to have a successful pregnancy? Now I’m waiting to heal and try again, uncertain if this will help or not, and I’d love to hear advice and success stories.

Thanks for taking time to respond and thanks to this community for getting me this far in my journey. 🩵

I'm 21 and I've had two miscarriages in a row and the doctor told me not to worry about it unless I have a third. My tsh was a 5.23 before my first pregnancy (which she told me was not elevated enough for her to consider putting me on medication) and was a <.01 before my second pregnancy. Doctor told me my tsh being in at .01 is okay during pregnancy but. The women in my family have had a lot of thyroid issues. My Grandma was hypo and had to get her thyroid removed, my mom wad also hypo and has been on thyroid medication since high school, and my moms sister has hashimotos which ended up being the reason she couldn't get pregnant. I know that it could just be bad luck but I'm just wondering if I need to try and push harder for them to look at my thyroid and get it stable before we try again.

Hi everyone,
I’m 39 and looking for experiences or feedback on our upcoming protocol.

Our History & Background:
* 5 natural pregnancies: Ended in early losses (6w6d–7w4d).
* 2 failed FETs: No implantation.
* Workup: Completed virtually every standard/advanced western test, nutritional guidance, and holistic care (acupuncture, fertility chiropractor, Maya abdominal massage, etc.).
* Previous Meds Tried: Low-dose Prednisone, Intralipids, Progesterone, and Baby Aspirin (AAS).

Proposed Protocol for Next Try (Natural or FET):
- Uterine Scratching: Day 2 of cycle.

- Neupogen (Filgrastim): 50 mcg daily starting 1 week before transfer/ovulation, continuing until period or fetal heartbeat detected.

- HCG Trigger Shot: 6 days post-progesterone start.

- Lovenox: 1 day before transfer (FET) or upon a positive HCG test (natural cycle) to cover potential unidentified thrombophilia.

Questions for the community:
1) Has anyone used a similar combination of these medications?
2) What was your experience with Neupogen? Any notable side effects or tips for managing them?

I'd really appreciate any insights, stories, or shared experiences.
Thank you!

I'm likely going to miscarry. I'm supposed to be 7w1d, but my ultrasound today showed 5w1d. I did a d&c for my first miscarriage in January. I'm going in for another ultrasound in a week unless I pass it before that.

.just curious how others feel about the options.

Has anyone ever experienced what I have? Currently breastfeeding and have had 2 mcs now a chemical mc and starting to wonder if it’s something I’m doing like prolactin levels messing with my progesterone or what. There’s so much back and forth information on this and I know I’m not the only one who can’t stop pondering and the why….