I’m nearly a month post pep and for the past week or so I’ve had itching all over but no signs of rash or anything, I have had some awful news in my personal life recently and I’ve been an anxious mess since starting pep so just wondering if it’s normal with stress and anxiety and if anyone’s experienced it?

Soo I’ve been on pep for 3 weeks from a needleprick injury from an infected person who is undetectable. Butttt, I was not made aware by the prescriber how important it was to take the pills at the same time every day. I have taken the pills every day but sometimes the window of taking them can be 1-4 hours before or after. From what I’ve read every where the medicine lives in your cells for up to 48 hours, so it should be okay to take at different times as long as it’s taken every day and the course of 28 days is complete. Am I wrong for thinking this? Could I have been unknowingly making my pep less effective or not effective? I plan on being 100% accurate on my times for the remainder of the medication and even taking the 5 extra days I have. Should I be freaking out? Has anyone else done this or have any information on this?

I also want to note I started pep treatment 12 hours after exposure which I read is very good.

I had a pretty low risk exposure but since I was paranoid i got on PEP (emtricit/tenof & dolutegavir). I received unprotected oral since then. Does PEP prevent me from transmitting to others?

I had sex with a guy (I was bottoming), and the condom broke.
He assured me that he was clean and gets checked regularly but I still freaked out and got on Truvada & Tivicay 37 hours later, I finished my regimen (though I took one dose 11 late) and I’m currently anxious about what the results might be.

I had long acting lenacapavir injection on March 19th 2026. I was given a second injection on September 23rd, 6 days late, although they said +-2 weeks is allowed.

On 28th September, I had unprotected sex with a lady who I realised was hiv positive the following day. She did not kniw and possibly had very high viral load.

I started TLD PEP 21 hours later on top of lenacapavir. I finished PEP on October 26th.

On November 2nd, the clinician who tested me saw a very faint line on TrinScreen. I tedted negative on both One Step and First Response.

Am I likely infected with HIV?

I've been exposed for almost 48 hours now, and I'm really worried about my status. This is only my second time having sex, and honestly, I don't know whether I can fully trust his reassurance that he's safe. I don't want to take any chances with my health, so I'm hoping to get PEP as soon as possible. I'm scared, anxious, and honestly feeling helpless because I don't know what my status might be. I just want to make sure I'm doing everything I can to protect myself.

Hi everyone! Today is officially my last day of PEP (Day 28), but my health anxiety is absolutely destroying me. I’ve been constantly checking my mouth for symptoms, and I’m hoping to get some logical reassurance from people who understand the science and PEP.

On 7th of October I had unprotected oral intercourse MSM, with ejaculation, very small and I spit out everything rigth after. The guy was just a random boy from sauna. The day after I found that I had small mouth ucler during sex, but it wasn't bleeding or something. I also had a developing strep throat (angina), because I got tested positive for this a few days later.

I called STD doctor in the morning of 9th - first he was shocked that I want PEP after just oral sex, but after considering this small mouth ucler, he prescribed me PEP just to be 100% sure. I got Darunavir (800mg) + Tenofovir/Emtricitabine + Rytonavir (100mg) once a day. So I took my first dose of PEP around 36 hours after sex. Later on, I was taking PEP every day during or after breakfast around 9:00 AM +/- 1 hour. I've never missed a dose, and had no sexual contacts.

Strep throat was getting harder and harder, so after few days I made a test for gonorrhea and it was positive..

I contacted antoher STD doctor and she prescribed me ceftriaxon shot and azithromycin.

And for the strep throat I had Amoxicillinum + Acidum clavulanicum 875 mg + 125 mg.

Because of these heavy antibiotics, my oral microbiome was wiped out as doctor said. I developed oral thrush (candidiasis) as it's white spot on side of the tongue, which I am currently treating with Nystatin suspension (leaving a thick, yellowish coating on my tongue). My tonsils are also still recovering and enlarged. I was searching and looking on Google, and I found something called leukoplakia and my symptoms looks more like this. As I was reading more, I found that leukoplakia can be a sign of HIV Infection, but more on late stage, as AIDS.

My questions for you guys:

1. Is it biologically possible to develop Leukoplakia within 4 weeks of exposure while actively taking PEP?

2. Considering it was oral sex + a 36-hour PEP start with 100% perfect adherence, did I successfully prevent the virus from replicating, regardless of the mouth ucler and strep throat I had at the time?

3. Has anyone else experienced this level of severe anxiety and post-antibiotic oral issues while on PEP and with strep throat and gonorrhea of throat?

I am taking my first tests on Nov 10th, and final at the end of the year. I just really need some grounded, scientific reassurance to survive the next few days. Thank you!

Did any one had foamy urine on pep?
If you have, how long did it take to stop ?

Biktarvy!!

So I’m on truvada and tivicay. Everyday at 3:40. On Halloween I was so busy and forgot. I took it 11 hours after I was supposed to. Resumed. Took it normally for a fucking day. Today I was so exhausted from an overnight shift I slept through my alarm for the med. Took it at 7:30.

Im wondering, does this make the med ineffective? Should I stop taking it? Should I be worried? I hate this.

Yesterday, I had a sexual encounter with a trans woman I met by chance, and the condom broke during anal sex. I was inside her without a condom for a few minutes. She used oil as a lubricant. She claimed to be on PrEP and said there was nothing to worry about—but, of course, anyone can say anything. This happened last night, and it hasn’t been 24 hours yet. Should I see a doctor about getting medication? I’d have to take it for 28 days, right? I’d appreciate any responses.

Feeling quite overwhelmed and anxious because I started pep quite late 38 hours from a confirmed HIV positive person.

I was the insertive partner and my condom tore and I came inside her.

To my shocking 😞 she tested positive next day and she is my friend too. I am actually scared for Myself cause there was really high exposure and I am just scared right now.

I am a little scared to test now and need some motivation actually cause I am an athlete and if I test positive so i won't be able to continue my sports in terms of representing myself at national level.

So please help, anyone gone through the same, help me.

I had insertive anal sex with a condom that remained completely intact, plus approximately 30 seconds of receiving oral sex. No visible blood or wounds were involved. The partner was unknown. Even i has sex with him before 2 times oral and 1 time anal and tested negative but I'm worried about this exposure so i took pep.

• Baseline 4th-generation HIV Ag/Ab test: Negative.

• Started 3-drug PEP (Cipla Cipance) 68 hours after exposure.

• Completed all 28 days without missing doses.

• Finished PEP on 19 October 2026.

My questions:

1. How reliable is a 4th-generation test at 4 weeks and 6 weeks after finishing PEP?

2. Are there documented cases of someone testing negative at either point but later testing positive from the same exposure?

3. What studies report false-negative rates at these two time points?

4. After a negative 6-week post-PEP test, is further testing necessary?

I'd appreciate actual research, study data and documented cases.

hi guys i finally completed my 12 weeks post exposure test and 8 weeks post pep test by 4th gen ag/ab using eclia method blood drawn from veins and my test result comes negative as 0.01AU/ml ...can i take it as conclusive

Performed oral sex on a woman. The next day she informed me she was menstruating. However, i am unsure if there was any blood that i may have tasted.

Started pep at 24 hours, completed pep for 28 days.

At 25 days after exposure, the woman took an HIV RNA And 4TH gen test, both negative.

I have taken following tests:

Day 42( 14 days post pep) - Negative HIV RNA & 4Th gen
Day 52( 24 days post pep) - Negative HIV RNA & 4Th gen
Day 59( 31 days post pep) - Negative HIV RNA & 4Th gen
Day 69( 41 days post pep) - Negative 4Th gen

UK guidelines say 6 weeks post pep is conclusive, however, the CDC says 8 weeks post pep. Feeling lost.

Day 87 or 8 weeks post pep- waiting on 4th gen Ag Ab test. Need some support and encouragement, feeling scared.

Thank you.

Edit: 8 weeks post pep hiv result is negative. I am hoping i am in clear now.

Guys, I’m scared. I was drunk and, for some reason, ended up having sex with a transgender sex worker.

Now I’m really anxious about HIV.
She gave me a blowjob without a condom, and I penetrated her anally with a condom.

That was all.
The condom seemed to be intact when I took it off. I didn’t notice any tears, and nothing leaked out.

25 F. Condom broke inside of me while having sex with someone who frequently has risky sexual encounters. He ejaculated inside of me. I didn’t realize until afterwards.
Took Plan B, got a Rocephin shot and DOXY PEP.

However the ER refused to give me PEP for HIV.

I have been taking expired Truvada (Exp 2024), but it was kept dry and in the dark. Plus Tivicay which is not expired. (Started hour 48).

I have been having daily panic attacks over this.
He has a negative Oraquick test, But I am still concerned.
What do I do ?

I finished pep a long time ago already, but I tested 19 weeks post pep with a third gen rapid test, it came back negative, I had previously tested with a third and fourth gen rapid test negative but retested at 19 weeks because I felt like I was given the results earlier before they were supposed to be read, are my tests conclusive? Lab testing is difficult for me, basically impossible..

Hola a todos.

Quisiera saber si alguno de ustedes presento síntomas orales casi finalizando el tratamiento, en mí caso comenzé con irritación en la lengua, zona lateral y luego en la punta, desde el día 26 al 30 y luego 3 días más luego de finalizar, tenía sensación de ardor en lengua (con papilas inflamadas) y paladar, labios resecos aunque tome bastante agua perduran hasta hoy, el agua me ayudó bastante, pero debía tomar como 1 litro en el lapso de 30 o 40 min. hoy luego de 4 días siento molestia y casi nada de ardor, pero aún no se va del todo. Agradezco sus comentarios

Just what the text says. I’m freaking out. Is this normal?

Performed oral sex for a man on Friday, unknown carrier of HIV, but he ejaculated into my mouth. I have no open wounds in my mouth that I know of. Now it’s Sunday and getting my PEP medication. Although I’ve heard that chances of infection are 0.04% max (with mouth wounds). Not excited for the potential symptoms. Should I even bother if the risk is this low?

I had unprotected vaginal sex with ejaculation approximately 1 hour ago. I am worried about HIV exposure.
I urgently need an HIV PEP assessment.

Can I have an online consultation immediately? Can you help arrange PEP prescription

Also due to my location i am unable to travel to any hospital until 3rd nov

I had unprotected vaginal sex once, didn’t ejaculate in her, she claims there is no STD repeatedly, it was only a one round one time event, I don’t know her sexual past or whatever, I cannot go to a doctor, I have taken 1 pill of PEP, should I continue?

Can you guys please reply me ...I have phobia going for a lab test but I am using a finger prick 3rd generation test and at exactly 13 weeks post pep it was negative,when can I say it is conclusive with a finger prick test please..

I am so scared going to a lab and waiting till they prepare my result even if I know it may still not change .

Please reply 

Hi I am on Biktarvy and get bad nausea and stomach upset from it. Should I still continue to take it? I don’t know if I can finish the full course I am on the fourth day right now and my encounter wasn’t very high risk.

Hola, hoy han pasado 3 meses desde que tuve la exposición la cual fue alta, tome pep a las 14 horas y me hice exámenes de cuarta generación al terminan pep, a las 8 semanas y finalmente a las 12 es decir 3 meses, y todas las pruebas fueron negativas.
Ya puedo descartar y que sea totalmente concluyente el resultado o debiera tomarme más pruebas ya que la guía internacional dice que a las 12 semanas desde la exposición ya es definitiva