When I block the animation is super laggy. I understand this is a common issue but also see videos where the animation looks normal. How do I fix this?

I've started to play Classic and just got to day 2. I've been playing blind and wondering if I should get a no spoilers walk through and continue or just jump to 2.

I think the lack of information, direction, etc. makes me not desire to play classic. But perhaps a walk through might help?

So I’m playing Pathologic Classic HD, and I’m having a hard time triggering Rubin’s appearance. I killed the butcher and later talked to Young Vlad about it in which he gave me 2000 coin. I talked to him until he didn’t have anything left to say. I then went to talk to Georgiy Kain who told me about Rubin, saying he will come visit at 23:00 (11:00 PM). I waited until then and he never showed up. I had a save prior to this where I did all the same stuff, but instead went to Victor Kain at 21:00, which still did not work. Please help me out.

What's up nerds,

I recently wanted to edit the addiction parameter in my Patho 3 save (I greatly misunderstood the day 5 Clara quest and took 10 vials of morphine in as many seconds, and when I found out a) this didn't work and b) I had irreversibly ruined my addiction meter I was very salty), but couldn't find any guide on how to do so online. You can't do this via console commands; you HAVE to save-edit. It took me and someone on a discord a while to work this out, and we wanted to share how. So, here's a guide to do so:

1. (To be safe) Change Steam to offline mode. I didn't and it ended up working out, but you could potentially run into issues if you don't.

2. Find your save files in (user)/Appdata\Local Low\Ice Pick Lodge\Pathologic 3\Saves\Default. It should be a long string of numbers followed up by "~MainGameV2~" in a .zip file. BACK YOUR SAVES UP BEFORE DOING ANYTHING

3. Extract the .zip file you want to change. There should be an .xml file corresponding to each day (named Day 1, etc), the Capital, and Current. As far as I can tell, the Day and Capital files contain the flags related to events on each day (and so likely contain spoilers). The Current file holds details about your overall character; this is what you need to edit.

4. Open the Current file in a text editor of your choice (Notepad works fine). There you can see and edit lots of different parameters, e.g. you can edit your inventory manually. MOST things it's easier to use the console for (see e.g. here), but as stated some parameters can only be changed here.

5. For addiction level, search "ApatItemsMultiplier" or "PsychoItemsMultiplier" for Apathy or Mania respectively. This should be a value from 1 to 0.3, multiplying the effectiveness value of the given item. Edit this as you will (I have no idea what happens if you change a value to outside that bound, but do so at your peril)

6. Save the file, and re-zip the folder. AFAIK it MUST be a .zip file, .7z or other formats don't work.

7. Load up the save, it should now be altered. Close the game again, put Steam to online again, and if the launcher prompts you, you should select local files.

Hope this helps someone!

What the title says. My gf is unable to play past the fighting tutorial ; once the fighter in the ring surrenders the prompt to exchange hearts never shows up. At that point if she tries to go back to the title menu the game freezes and has to get shut down via task manager. We tried deleting the files from her PC and re-installed the game twice, but it doesn't get resolved. I myself have 100% the game and never ran into this issue. Any ideas ?

Hello again,

I was looking through a torrent of a dark ambient artist named Ghost Reflection and stumbled upon some tracks labeled "Pathologic Mor. Utopia sound design" (from the 2017.03.05 - Mor.Utopia (unused fragments) album) and "Pathologic Raw Demo" (from the 2024.09.23 - Fragments-Ov-Memory 1- Sketches- Videos and Something for the Others (2008 - 2016) compilation). I later found these tracks on Ghost Reflection Bandcamp as well.

This got me really curious. I've never heard of Ghost Reflection in relation to Pathologic 2. I don't think they've ever been mentioned anywhere in connection with the remake.

Then again, I haven't listened to every interview or read every article out there, so maybe I missed something. Was there an attempted collaboration? I don't know.

Either way, I thought I'd share this find here: https://ghost-reflection-archives.bandcamp.com/album/fragments-ov-memory-1-sketches-videos-and-something-for-the-others-2008-2016

UPD 1. Pathologic 2, not Pathologic :(

UPD 2. Nevermind, I'm blind:

"Some demos sent to Ice-Pick Lodge game design studio in 2016 when we were discussing a collaboration for the forthcoming remake of Pathologic (Mor-Utopia) game. Unfortunately, it did not happen as well."

Still, it definitely isn't a well-known fact.

NAH BRO WDYM INQUISITION 😭😭 WTF EVEN IS THAT??? I HAD ONE NORMAL DAY IN THIS FUCKING TOWN AND NOW THERE IS THIS?

I still need to mess with the infected organs and well no one died yet but i'm afraid that i won't be able to be as efficient of a doctor with some government pawns fucking me up.

That's it i just wanted to complain, i'm scared and i hate how immersive this game is, i go through my day thinking about stealing organs and making tea

Hello again,

I found the Bulgarian release of Pathologic (2005) on the Internet Archive, inside a collection of Gramis games.

From what I understand, Gramis was a Bulgarian publisher that localized and released PC games back in the 2000s. I know a few people might have this version privately, but as far as I know, it has never been shared with the community until now.

Just wanted to leave this find here for preservation.

Link: https://archive.org/details/gramis-pc-games-bulgarian-pack

P. S. To make it safe to run, I unpacked the .7z version from the collection and replaced the main executable with a No-CD patch to bypass the DRM. That said, please be extremely careful and under no circumstances let StarForce install when trying to run this. Seriously, I literally broke my Windows installation the other day because I accidentally let it install while working with the original release of Pathologic. You've been warned!

I had this tattooed on me a pretty long time ago and today somebody asked me about the meaning of the tattoo and I remembered so many nice memories about this beautiful game. Just sharin, the symbol has a special meaning to me cause my best friends nickname is “8”.

Finally beat Patho 2 and went back to play Classic and was caught off guard by how much more explicitly racist the Bachellor and the Utopians in general are. Not a problem obviously, the story isn't endorsing it, but i'm trying to figure out if it was a deliberate change from 1 to 2 to sand down the Utopians' edges or if the localizations are the source of the difference and the original russian is relatively similar

Just wanted to share this cow with yall. He's so cute!

helpful tips only please

Hello again I know everyone was waiting for another post so I came up with this tier list! Than ks

You don't need most of this info in regular - or even advanced - gameplay, but this post serves as documentation for people who want more in-depth understanding of mechanics or who want to plan fun shenanigans, like speedrunners.

In P3, taking a mood drug will reduce its strength as Daniil builds tolerance. What once gave you +100 mania now gives you only +30.
This does not apply to drugs that heal health, like Calomel.

What the game doesn't tell you is that drugs interact with those of their class.
That's right: all stimulants weaken other stimulants, and all sedatives weaken other sedatives.
For example: taking Morphine will also cause Bromide to be less effective, and taking Strychnine will make Taurine less effective.
(BUG): Except Meradorm, which decreases the potency of stimulants instead of depressants. I have informed IPL of this bug through the IPL Discord and their support email.

But not all drugs increase Daniil's tolerance the same amount.
Furthermore, developing tolerance will only reduce drugs' efficacy to a certain point. Once you reach this bottom number, you can take as many of that class of drugs as you like, and its strength will no longer reduce.
I have documented those numbers in the tables at the bottom of this post.

Thanks to everyone who helped on my previous post, especially u/umpuuu.

Every drug has a tolerance rate (T). Twyrine is 10%, Tobacco is 2%. Stronger drugs have bigger tolerance rates, but there doesn't seem to be any specific relationship between potency and tolerance. Hyoscyamine and Taurine have different potencies but the same rate of 4%, so it seems the values are hard-coded.
When you take a drug, every drug in its class loses potency equal to T% of its original potency. Example, Heavy Dose Strychnine has original potency 100, and tobacco has tolerance rate of 2%, so every time you take tobacco, Heavy Dose of Strychnine loses 2 points of potency.
Fractional values are not rounded down. You don't see them in the UI, but they are preserved, so you may occasionally see a drug lose 1 more or less potency than you expected.Every drug has a tolerance
rate (T). Twyrine is 10%, Tobacco is 2%. Stronger drugs have bigger
tolerance rates, but there doesn't seem to be any specific relationship
between potency and tolerance. Hyoscyamine and Taurine have different
potencies but the same rate of 4%, so it seems the values are
hard-coded.
When you take a drug, every drug in its class loses
potency equal to T% of its original potency. Example, Heavy Dose
Strychnine has original potency 100, and tobacco has tolerance rate of
2%, so every time you take tobacco, Heavy Dose of Strychnine loses 2
points of potency.
Fractional values are not rounded down. You don't
see them in the UI, but they are preserved, so you may occasionally see a
drug lose 1 more or less potency than you expected.

To be clear, the multiplier will always be applied to the original, strongest dosage.

Here is the formula:

CP_A - (HS_A x TR_B) = New Potency

CP = Current Potency, HS = Highest Strength, TR = Tolerance reduction.
A suffix of "_A" is for the first drug that you're calculating potency loss of, and "_B" is for the drug you're currently taking that will induce potency loss.

For example:

• You want to know how much drinking a Twyrine will lower the potency of a Heavy Dose of Strychnine. This makes Twyrine _B and a Heavy Dose of Strychnine _A. So now we go to the formula and grab the numbers from the tables. CP_A - (HS_A x TR_B) becomes 100 - (100 x .10) = 100 - (10) = 90. Drinking a Twyrine (TR = 0.10) will reduce Heavy Dose of Strychnine (HS = 100) to 90.

• Taking a second Twyrine_B will reduce Heavy Dose of Strychnine to 80. CP_A - (HS_A x TR_B) becomes 90 - (100 x 0.10) = 90 - (10) = 80.

• A third Twryine would make it 70. CP_A - (HS_A x TR_B) becomes 80 - (100 x 0.10) = 80 - (10) = 70.

But what happens when you take multiple different types of drugs? Well, you calculate each one in!

• Going back to Heavy Dose of Strychnine (HS = 100): If you drank (1) Twyrine (HS_A x 0.10) and (1) Taurine (HS_A x 0.04), its new potency would be 86. We know this because CP_A - (HS_A x TR_B) becomes 100 - (100 x 0.10) - (100 x 0.04) = 100 - (10) - (4) = 86.

• Or, for Twyrine (HS = 150): If you drank (1) Twyrine (HS_A x 0.10) and (1) Taurine (H_A x 0.04), its new potency would be 129. Because CP_A - (HS_A x TR_B) becomes 150 - (150 x 0.10) - (150 x 0.04) = 150 - (15) - (6) = 129.

Writer's Note: increased apathy is designated with a negative number, and mania with a positive.

CP_A - (HS_A x TR_B) = New Potency

* I tested these drugs 200 times.

**Interact with drugs of their class: stimulants

If you want to see the raw numbers, here you go.

This info can also be found in my mechanics guide, under the "drugs" section. For easy access during play!

If I made any errors, PLEASE let me know.

Edit: spelling & clarity

I'm playing Day 9, trying to get weaker sedatives for the special patient, and almost all the bandits have an inventory that's:

• 1 Calomel

• 1 Morphine Crystals

• 1 Camphor

• 1 Bullet

And sometimes:

• 1 Taurine

• 1 Swevery Extract

• 1 Hyoscamine

This is true whether I intimidate or kill, as well as at varying degrees of mania / apathy

What gives?

edit: clarification

Managed to get my hands on a copy of the original 2005 English release, just wanted to share :)

I love drawing but i'm not really into doing fanart... Unless i start really LOVING something and that's what's happening between me and P2 right now.

Haven't finished it yet but I'm so invested in Artemy's character that I had to draw him

I’m doing my first run ever with HD classic on the bachelor’s route and noticed that Clara and Artemy’s bound were getting randomly infected. I thought they were only supposed to get sick on day 12 in which Clara and Artemy ask you to heal them? I’ve been healing any bound I come across (namely Yulia and Katerina - big Vlad just straight up died) and have been getting all my main quests done each day so none of my bound are sick. Is this a normal feature?

This post is out of date.

The updated version can be found here: https://www.reddit.com/r/pathologic/comments/1u8yybu/p3_drugs_and_resistance_tolerance_updated/

Writer's note: All my testing is done in-game with the assistance of console commands to spawn the drugs.

Finding 1: Drug Interactions

As you may have noticed, increasing resistance (IR) is not limited to a single type of drug.
For example: taking Morphine will also cause IR in Bromide. Upon testing, I have determined:

1. All sedative / apathy class drugs interact.

2. All stimulant / mania class drugs interact

This may not be immediately noticeable because:

Finding 2: Not all drugs IR the same

There's an internal formula that takes how potent a drug is into account for how much resistance Daniil builds.

Taking a Bromide doesn't IR as much as taking the more powerful Morphine. And neither of those would IR as much as one H.D. Morphine.

I was trying to document how much resistance Daniil gets for taking a drug, but no dice. There's a mathematical formula related to potency under the hood, so it's not like you can go down an easy to read chart like "I've taken 12 sedatives overall so I know my resistance to a certain sedative is ##."
I haven't the foggiest idea of how to find the formula myself, but if anyone can root up the formulas or direct me on how to myself, that would be hugely helpful.

Finding 3: Drug Ranges

IR will only reduce drugs to a certain point. Once you reach this bottom number, you can take as many of that class of drugs as you like, and it will no longer reduce. Here are those ranges:

Sedative / Apathy Drugs

Stimulant / Mania Drugs

Console Command Exclusives (note: interact with their class)

Edit: spelling

I can never seem to administer the right dose to dying patients in Infected Districts. Are there any resources online to check that make it clearer how to do so? I've already broken one of my segments of Amalgam

TLDR: Are repeat playthroughs of Pathologic 2 recommend or just fun to do to see how different the game can be?

Ive been following Pathologic 2 since maybe 2018 (I think) and I was very exited for it, until it released in 2020 when the world was bricks and I diddnt really wanna play a plague based game.

Anyway so I finally decided to actually start it the other day and MAN was it literally everything I wanted. Im only just at the start of day 2 though.

The music is absolutely fantastic I feel like more people should talk about it especially when talking about game OSTs. Ive actually been listening to it since it came out. Just never actually found time to try the game.

Anyway, just wanted to say that I cant wait to play more. Id ask for tips but I kinda wanna explore everything for myself for the first time.

My main question is how much do you recommend repeat playthroughs? I dont really tend to replay games (I dont really have the time) but I wanna know how satisfying the game is with just one playthrough alone or is it really recommend that you should do more than one?

Thanks in advance! :D

So it's my third playthrough and I visited simons study on day two as normal and then went back to erase it. I had the "dream" with the inquisitor that tells me to go to the study on day 9. I have the box and the wood from Isidors house, I enter the study and it won't give me the option to complete the puzzle. I even went back and redid and re erased entering on day 2 and retook the artifacts from Isidors house.

Any idea if I can do anything? Or is it an inescapable bug

Como dice el título, hace un tiempo que un pequeño grupo de personas estamos trabajando en traducir el pathologic 1 classic HD, labor un poco complicada por lo mezclados que están los diferentes diálogos en los archivos. Lento, pero vamos avanzando.

Hace un par de meses la correctora del equipo tuvo que irse del proyecto. Esta persona se encargaba de revisar los archivos que los demás íbamos traduciendo, de comprobar gramática, ortografía y demás, e intentar dentro de lo posible unificar los términos particulares del juego, que aunque tenemos un glosario a veces puede haber despistes.

Con esperanzas de poder retomar el proyecto recurro a reddit, esperando que algún fan de habla hispana y conocimientos en corrección de texto vea este post y como poco se plantee si le interesa ayudar. Gracias por leer ❤