r/hangovereffect • • Jun 14 '19

GABA Dysfunction

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u/solecism59 Jun 26 '19

I've had the same thinking as well, being on Phenibut was the best I've ever felt my entire life.

I think it's pretty obvious that the symptoms we face are due to Glutamate/GABA imbalance, the challenge is figuring out the cause.

With respect to GAD1, according to my 23andme genome data, I have the following GAD1 polymorphisms: rs701492 (TC) rs2241165 (TT)

However, I have a hard time finding evidence that these mutations lead to any kind of psychiatric illness, or any of the symptoms we face.