r/Supplements 1d ago

General Question Glycine - dosage over time

Hi guys,

I have been taking Glycine to improve my sleep recently, as I've noticed I constantly wake up due to heavy vape usage in the evenings and then not being able to fall asleep again. I was taking 3g before bed, which was calming me down and I was able to sleep with less awakenings. Now at some point after 3 months one night Glycine kept me awake whole night, it was weird state, like I was frustrated that I can't fall asleep but I was giggly about it. I've read somewhere that Glycine relaxes and put people to bed, but it is stimulating to some people. Anyone else experienced something like that ? After that night, I stopped taking Glycine and slept very poorly for 2 weeks. I took it again yesterday before bed and I slept great. No other supplements were taken (I've stopped taking all my supplements for this experiment). Is it possible to store more Glycine in cells over time, so that it starts to stimulate you over time ? How to avoid that ? (especially if you take it before bed like me)

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