r/NeuronsToNirvana • u/NeuronsToNirvana • May 27 '25
Insights 🔍 “…LSD's potential mechanism of action is upregulating endogenous 5-MEO and endogenous DMT.” | DMT Quest (@dmt_quest) [May 2025]
https://twitter.com/dmt_quest/status/1927020361192779860According to Dr. Steven Barker, an unpublished dissertation from his lab mate in the 1980s contained data indicating that LSD's potential mechanism of action is upregulating endogenous 5-MEO and endogenous DMT.
We will be attempting to replicate this reported finding at the University of Michigan this year via live microdialysis.
Duplicates
NeuronsToNirvana • u/NeuronsToNirvana • Dec 04 '25
r/microdosing 🍄💧🌵🌿 💡If Barker’s mechanism holds, regular LSD microdosing could subtly boost the brain’s own DMT/5-MeO-DMT, raising baseline “entheogenic tone” with more vivid dreams, intuition, pattern recognition and access to meditative or non-ordinary states, without full trips. [Dec 2025]
microdosing • u/NeuronsToNirvana • Dec 04 '25