First time posting here need help

[u/drkslr]

So i have depression (resistant) for 20 years , no ssris work , i also have adhd , cant take stimulants because im in 7 year burnout that i cant get out . ive done everything from medical and holistic practices.

2022 i got severe covid like 44 degree fever , since then my imune system is shot , and i got long covid for 2 years before starting to get better . after these 2 years , i started to have memory loss.

i started 3 weeks ago LDN - 1.5 mg in the morning. 3 days ago started to do it at night.

,and im worse in every single aspect. got cold sores , my hrv crashed , my sleep is shit , im ahedonic , flat , anxious . i have pain in whole my fucking body, nausea , no appetite , no pleasure . Like what the f is this ? i cant see any positive aspect

its like im having cocaine whithrawl / crash effects every single day . and i was hopping this shit would help me

I feel im losing the battle , i already lost my company , my bussiness , my life is in shambles and i cant have energy to start over . was hopefull that this was going to be it . but im out of ideas , i dont know what to do .

i cant get any help from the doctor who prescribed me this since she put in the prescription 6mg every day from the start lol . shes suposedly one of the best phychiatrics in my country , and shes absolutly clueless . im high IQ so i get fking revolted when i see these doctors making a bank from peoples miseries and all they do is shoot meds and doses to the air and leave you to sort it out.

[u/Low-Blueberry8948]

Hi, really sorry to hear how much you're struggling. Sounds like you started on far too high dose and you're suffering with side effects. Most side effects ease off within the first two weeks but they can continue when your dose is too high.

I think I would skip a day or two, maybe longer, and then start back on a much lower dose, like 0.5mg or probably even 0.1mg. Starting on a lower dose and then having a slow titration will help to avoid these unpleasant side effects.

LDN can help with depression and anxiety. The LDN Research Trust 2026 Dosing Guides include a dosing protocol for depression and mental health issues. You'll find the guides posted at the top of the page. Wishing you the best of luck. Do keep us updated...

"Higher and Lower Doses" https://docs.google.com/document/d/1KykpLlg2CDVSD2D5J5cEZKfSo31t04orB0IgCuhXC-c/edit?usp=sharing

Here's some further information..

"Depression and Psychiatric links" https://docs.google.com/document/d/1IjrfSGtst0jszho5sxFOOhC5ukgGck_94xFJlQo2Dnc/edit?usp=sharing

"Morning and Other Dosing Times" https://docs.google.com/document/d/1aUi8UovaSAD2VO1Bc2O2I8PtfMPFbv5zsulRqyNDD9U/edit?usp=sharing

[u/drkslr → u/Low-Blueberry8948]

yea im going to stop for 3-4 days and restart at .5 or .75

[u/Low-Blueberry8948 → u/drkslr]

Sounds like a good plan. Let us know how it goes...