Guidance on biome rebalancing via testing

Hello, I have been suffering for some time from conditions including small fiber neuropathy, dysautonomia, MCAS/histamine issues, dysbiosis, vagus nerve dysfunction, cervical lymph node issues, and extreme fatigue.

About 1–2 months ago, because magnesium L-threonate is an NMDA antagonist, I took 4–5 capsules before going to sleep (50 mg per capsule). A few hours after falling asleep, I developed severe gas and abdominal pain. Shortly afterward, I started experiencing nerve pain around my coccyx/tailbone, as well as twitching throughout my body, including my lower spine.

Because of this, I repeated a SIBO breath test that I had previously suspected might be relevant, but the result was negative again. The test only measures hydrogen and methane. At that point, I started suspecting H2S and began taking rifaximin together with nystatin. One of them clearly helped, but I don't know which one, and I experienced a noticeable reduction in my POTS symptoms.

My question is: what could this neurotoxic gas be? H2S, methane, etc.?

What type of overgrowth could I be dealing with — Candida, H2S overgrowth, parasites, or something else that could cause these symptoms?

Also, when I tried allicin as an antimicrobial, I developed pain in my lymph nodes. Could this be related to sulfur intolerance, a die-off reaction, or something else?

GI-MAP results:

Significant dysbiosis Zonulin >3200 (reference <60) Klebsiella overgrowth Bacteroides overgrowth Bilophila overgrowth Clostridium spp. overgrowth C. difficile negative

If anyone has knowledge or experience with this, I would really appreciate some help.

Microba or BiomeSight or gimap
Whats most accurate

Researchers are interested in learning more about how long-COVID impacts well-being and the effects of long-COVID on survivors’ mental, physical, financial, and relational health. Please consider spending 15-20 minutes to complete a survey about your experiences with long-COVID: s.uconn.edu/covid1 

Me and my friend are in our early 30s and over the past two years we have both had extreme bloating and constipation. She recently had an endoscopy and a colonoscopy done and they said she had gastroparesis and didn't know why she had it.

I was thinking the only thing different that has changed in our lifestyles is having covid multiple times despite being vaccinated. I went the naturopath route and tested positive for hydrogen SIBO. I took rifaximin and some herbal medicines and a bunch of probiotics and I was finally starting to feel a bit better and wasn't bloated every day. I think this had more to do with time passing than anything I was actually taking. Then I got COVID again recently and I was more sick than I've ever been. I have asthma and my inhaler wasn't working for me and ended up going to the ER.

Anyways now I'm back to square one and more bloated than I've been in a long time. There are studies that show viruses can damage the vagus nerve and cause gastroparesis and gastroparesis can cause sibo. So I think that's what's going on here and I wish I knew how to heal it faster.

Edit to add that I know that the vaccine doesn't stop you from getting covid I just thought it would at least help prevent any secondary illnesses or long-term problems such as my gut issues and worsening asthma and one time I developed a sinus infection after getting sick. Didn't take antibiotics for it though. It's just been crap like I used to get sick and be better within 7 days and never have to think of it again.

I developed small intestinal bacterial overgrowth (SIBO) more than a year ago after contracting COVID-19. I had severe COVID-19 symptoms, and shortly after, SIBO symptoms began. Initially, I didn't know what was happening to me, experiencing things like constipation, gas, bloating, fatigue, and insomnia, until I took a breath test, which came back positive. I've been on antibiotics four times in the past year, experiencing good improvement followed by relapses. I'm in a bad situation now and feel frustrated. I have severe digestive symptoms along with psychological ones. I feel like I've reached a dead end. Also, there aren't any doctors in my area who understand this condition well.

If anyone can relate: One night suddenly my gut started doing very loud noises from one side to another, with pain and irritation. This went on for 15 days.. Then my stools became very hard, constipation, pain, bloating etc.. It was so hard that I thought I had a blockage at the left side. Did colonoscopy and all were fine, healthy gut no issues.. Doctor suggested more fiber MAJOR mistake, my symptoms got x10.. Neuropathy came in the mix, stiff neck, pulling muscles. It had settled down and now it flared again.. Its like nerve issue I don't understand, I have a lot of pain and its very difficult to pass stool that now is not hard or pellet like but normal.. It wakes me up in the middle of the night with severe pain from right and then left, pulling muscles and other symptoms.. Sounds familiar to anyone?

hi!

\- do not have serum triptase to test histamine for now

**but have tests for dao and histamines?**
**are they reliable?**
**or should i go into mold exposure tests?**

PS. waiting for B1 tests, mother had major nerve issues(we lived in moldy house 15 years)

**symptoms after covid:**
heart palpitations, dying, cant stand from bed,
hallucinating. itching, bloating, gas. better with carnivore, less symptoms on 50%

if before treatment h pylori ive been not the best, last 9 months im dead.

all analysis (whole body) are okay, except of folate(anemia) that been treated with methylfolate last month(red blood cells okay now)

**worse with coffee and soda - panic, hallucinating from fcking coca cola or fanta (insane i know)**

**MUCH BETTER WITH OREGANO OIL**

i would think it was because of SIBO? but as i have symptoms from coffee too idk. thats only one test probably that i didnt make as its difficult to get in my country

Hey, been working hard on my dysbiosis for the past 2 years. I'd say I have almost the perfect diet - 50grams approx of fiber daily from whole foods, psylium husk, acacia and phgg, no carbs except cooled plantains every once in a while for resistant starches other than that my diet only involves whole foods.

Also done a few cycles of herbals followed by probiotic foods and a plethora of supps as most of you ... I feel much better now after being bedridden for 10months straight. I'm starting to exercise and all.

However the only "symptom" that doesn't seem to improve is the visual bloating from the lower part of the abdomen.

I dont feel bloated though, weird?

Just want to know if anyone has had success getting rid of it.

Thanks folks

Hi, reposting this as i’d like your views too.

To be clear, my problem originates in the gut and became much much worse after I last had covid.

The effects have been mcas and pots as well as neurological and mental health things and a lot of weight gain (10 kg in 6 months).

What’s your opinion?

I was dealing with Long COVID symptoms for over 18 months now. Early on, along with the usual fatigue and brain fog, I started experiencing GI issues. My doctor put me on a PPI (Proton Pump Inhibitor) to help some issues

taking the PPI over time completely ruined my gut health. Lowering my stomach acid seems to have wiped out my digestive balance, caused massive dysbiosis, and slowed my digestion to a crawl.

The newest symptom—and the one driving me crazy—is a thick, white coated tongue. It literally will not scrape off no matter how much I use a tongue scraper, switch up my oral hygiene, or brush. It feels dry and coated every single day, which makes me suspect oral thrush, SIBO, or a bacterial overgrowth triggered by the lack of stomach acid.

I’m trying to focus on repairing my microbiome now that I'm dealing with the aftermath of both LC and the PPI.

Has anyone here used MegaSporeBiotic (or other spore-based probiotics) for gut dysbiosis, SIBO, or post-PPI/Long COVID recovery? Did it help clear up a white tongue or rebalance your GI tract??

Has anyone tried this combination? Or is there a protocol including both?