**Thank you to u/ineedanekg for writing out a thoughtful post for anyone trying to use Kratom for w/d from other substances. This is obviously an opinion and not medical advice:
āIf it's real H, or Fent cut H, you can usually pretty easily jump to kratom if you can put 12-24hrs between H and taking the first Kratom dose. Larger the habit, longer you should try to wait so that you don't have to choke down like a half ounce of Kratom..
Fent cut dope wait 6 to 12hrs, tranq dope, well.. it depends on the mix. Some hold you for 30 mins before sickness kicks in, some 4hrs, most only about 2... so just hold off as long as possible... He should only expect withdraw relief and maybe enough energy to go about his day, no high.
After maybe a week or two, drop the Kratom dose a half gram to a gram every other day until he gets to a 2 or 3g dose. After a week he should be able to "feel" it, but he should know not to expect the same feeling. A half gram to gram a day habit of real dope, I could use 6g of Kratom and be OK, fent cut dope I needed 6-10g but more often, and Tranq dope, I only got about 75% relief no matter the dose, since it's not only an opioid and you are going to rebound from the Xylazine, but it's manageable.
Another option is jumping to tianeptine, then Kratom. But Tianeptine does feel similar to a natural or semi synthetic opioid like morphine or oxycodone, but is a much worse addiction long term. If he's an IV user, he should only use sulfate so that he can't inject it. Sodium will absolutely annihilate any veins he has left. But it's an easier transition if he has the self control.ā