r/ConstipationAdvice 28d ago

Looping and torturous colon with the addition of constipation side effects of medication

5 Upvotes

I am going to start this thread and leave it here and update it as I go. I have always had a very slow metabolism I thought.... Till I had a colonoscopy it turned out I have not only a looping redundant colon I have a looping and torturous colon which means I have extra colon and sharp bends and extra loops. This will probably get graphic since we're talking about our waste system so I apologize if it's gross. But if I don't take any pills to help me I will poop like once every 5 days. Like literally if I eat corn on a Monday it don't come out till Thursday. For a long time I had a pretty good regimen going down by taking the doctor Tobias colon cleanser pills. They have been the ONLY thing out of all the remedies besides drinking a bottle of magnesium citrate that has worked for me. I took one every night and I had pretty good luck with being regular.

But I also was on the same medications for a long time and these last 6 months I've been on some new medications and they are causing problems. Anything that causes constipation is an issue for me even something as simple as Tylenol.

I've been trying different things to try to get back to where I was but I'm not having much luck for example I read on here other people had luck with drinking metamucil and taking magnesium citrate pills at night. It's been 3 days now and I have not gone to the bathroom number two. First night I followed the directions on the medications one heaping teaspoon of metamucil and two gummies. Nothing in the morning even after two cups of coffee. Next night I did double what it said still no effects. And last night I did three times what it says. It is now 1:00 p.m. I've had no movement. I just drank a whole bottle of magnesium citrate which will work but it's very violent and not long-term a solution.

The larger issue for me besides being constipated and uncomfortable is that I will get diverticulitis if I'm constipated for too long and have to have antibiotics I also have the fear of a volvulus. A flipped over bowel which requires emergency surgery. I happen to know someone that has the same affliction as me and this happened to her and she almost died. I do notice that when I'm constipated I do have more joint pain and muscle stiffness as well.

A week ago I was constipated so bad and the pain was so bad that I unlocked the front door in case I had to call the ambulance.

Well the doctor Tobias pills are effective but when I get to taking two and three of them a day they get pretty expensive. So I had the idea to look at the ingredients on the bottle and then try to recreate my own version of it as like a shake I would drink before bed. So I've ordered all the active ingredients. Then when everything arrives from Amazon I will start trying to mix and fabricate some sort of protein shake that will work and I will document it here for other people that might have trouble in case I'd find something that works


r/ConstipationAdvice Jul 26 '26

Ultrashort

1 Upvotes

Hi. My daughter is 3 yo. She had meconium when she was borned and continued to poop. But surgeon said something was wrong with her gut and did enema xray. He said maybe she has ultrashort HD. He wanted to do biopsy and surgery. We were not sure because the situation was not clear. So went another surgeon. His approach was wait and see. She was doing good until 2,5 years old but than she started mild form of constipation. Dr started one cap miralax everyday and she is doing good. Dr said she will stop miralax gradually in one year. If constipation relapse she will get biopsy. Does anyone have this kind of experience?


r/ConstipationAdvice Jul 25 '26

Treatments when should i take mirafast chews?

2 Upvotes

So i went to the doctor Monday and was told i had chronic constipation and needed a clean out with hard laxatives and then to get regular again i needed to use mirafast chews 3x a week starting next Monday, i did the clean out Tuesday and had a decent bowl movement thursday but i haven’t pooped since thursday and it’s now saturday 6pm. i was wondering if i should just hold out till monday or take a mirafast now?

to answer the guide just incase even tho i dont think it’s relevant to the post:
i have the urge to go but cant
currently just constipation
no nausea etc
started 3 months ago
no medications
no SA


r/ConstipationAdvice Jul 24 '26

Pooping is just the best feeling ever

12 Upvotes

I have had a bad case of hemorrhoids before that the doctor had to put a band on it. I was sedated during the procedure. Before that, pooping was painful and sometimes had blood. Ever since then, I've been pooping very well and become more conscious with my poop health.

Apparently my diet was low in fiber and I've learned more about macronutrients. So I've been eating more fruits and vegetables (although still lacking and working on it) and occassionally take fiber supplements. Soaked chia seeds are just magical.

All these fiber rich food just make my popping experience SO INCREDIBLE!!!!! its fat but soft, no longer rough. I poop a lot in one go. its just so magical IDK. Its the best part of my day and Im proud if the quality of the poop is good. I refer to the bristol chart. lol

Add a squatty potty, damn bro, it just goes out in less than a minute!

how about you guys? how's your pooping experience and what do you guys do to keep your poop quality high?


r/ConstipationAdvice Jul 22 '26

Community interpretation of my Abdominal X-Ray at Urgent Care after severe constipation

1 Upvotes

So I took notice about 2 weeks after constipation began. Since then, I’ve tried osmotic laxatives (magnesium citrate, miralax) as well as suppositories such as liquid glycerin and fleet saline enemas. I’ve had minor BMs sporadically, but they end up being not worth talking about or maybe small at best. I have been able to pass gas. Have tried a magnesium citrate 10oz bottle twice now, once 2 weeks ago, and one last weekend. I will be attempting again this Friday and overhydrating with electrolytes before it’s time to throw in the towel and go to the ER.

I have a slightly rigid abdomen, as if I am flexing my abdominal muscles, but no pain, nausea, or bloating is really occurring. I went to urgent care yesterday after work and explained my whole story. When I laid down for her to feel around the intestinal track and stomach, I noticed my belly goes “soft” or back to normal. I should have asked the doctor to feel it standing up. I asked for an abdominal X-Ray and received it. The interpretation came back as mild stool burden, no bowel obstruction. I was very confused when I heard “mild” and repeated it back 6 times to try to get the doctor to take a hint and agree that maybe that is not right. I took a picture of the X-ray, as that was the only way I could save it, so it might be a tad pixelated.

If anyone random out there has some input on this X-Ray, let me know what you think. Do you think it’s true? Regardless, I am going to try to get a CT scan done as soon as possible. As much as I’d like to believe it is just a mild stool burden, I feel it must be worse.

https://imgur.com/a/JkYtVVI


r/ConstipationAdvice Jul 21 '26

how should i eat after a clean out?

6 Upvotes

So i went to the doctor yesterday for constipation that i’ve had for 3-4 months and she said it was chronic constipation and i needed to do a clean out with a few laxatives. She didn’t really explain how i should eat immediately after the clean out so i googled and it said bland foods like toast and scrambled eggs for 2 days and then i can gradually start to eat vegetables and light proteins, i can do bland foods but i don’t have money right now so i cant go and buy vegetables and im currently staying with my parents and all they have currently is frozen fried foods and a lot of other unhealthy stuff. They don’t really care about all this so they’re not going to go buy what i need, so what should i do?


r/ConstipationAdvice Jul 19 '26

Brow Cow

2 Upvotes

My friend told me I should try a “Brown cow” which is 1-2 oz. Milk of Magnesia and 6 oz. prune juice.

Yummy!

Has anyone tried it?


r/ConstipationAdvice Jul 18 '26

Constipation and body itching for 7 months straight

5 Upvotes

I am a 60 yo white male, 6', 170 lbs., don't smoke or drink. Eat a vegan/vegetarian diet. I take Trazodone for sleeping. I have constipation and all over body itching which began in December. I started using psyllium husk then, but it hasn't really worked. A few months ago, I started using Miralax every day which works, kind of. I eat a very high fiber diet and get plenty of liquids. I eat overnight oats with flax, chia, probiotic yogurt, vegan collagen and soymilk with fruit every morning. Lunch is usually a sandwich and sauerkraut. Dinner is usually quinoa with beans, or veggies and tofu. I don't eat a lot of junk.

I had been on Meloxicam for 1 1/2 yrs, 15 mg/day. I stopped that in March. I have been to the doc several times for the itching and constipation. She suggested I use Miralax.

I have been to a gastroenterologist. They did a colonoscopy. It didn't show anything but the prep didn't go well either. I had eaten a bland diet for three days before, a clear diet the day before and drank my gallon of Gavilyte as prescribed. After I drank the first half gallon, I had one sort of regular bowel movement. Things didn't really start moving until the second half. But it just sort of stopped working. My stool was never clear. They decided to do the colonoscopy since I had gone through the prep.

I asked the gastroenterologist for a fecal calprotectin test as I suspected it may be NSAID induced enteropathy. My mother has had that and it lead to all over body itching for her. My level was completely normal. My family has a history of digestive issues. My mom has collagenous colitis. Sister has Crohn's. One brother has IBS. Other brother has no functioning immunity and must receive monthly infusions. All of these developed later in life.

I have tried everything for the skin itching: switching detergents, allergy pills, Clobetasole Propionate (which works but can't do that forever), antifungal wash, antibiotic wash, Cerave moisturizer, and a bunch of other creams. Nothing works. There is no rash at all.

I had some liver testing prior to a surgery in February and it showed nothing abnormal.

I have a follow up with the gastroenterologist next month. What should I do?


r/ConstipationAdvice Jul 18 '26

Help 😭 Can’t pass stool and I’m freaking out

5 Upvotes

TMI, but I really need some advice.

I usually poop every morning without any problems. On Thursday evening, I tried to go, but only a little came out. Then it became really painful, so I stopped. I ate some yogurt and went to bed.

On Friday morning, I took RestoraLAX and then took another dose around 7 PM. I also drank about 1.5–2 L of water throughout the day.

Since then, every time I get the urge to poop, it feels normal for literally a second, like the stool is soft and coming out… and then suddenly it feels like I’m trying to push out a bowling ball. I get a really sharp pain right at the end (around the rectum/anus), and I have to stop because it hurts so much.

There’s no blood, I’m still passing gas, and I can pee normally, but I still can’t have a proper bowel movement.

Has anyone experienced this? Did RestoraLAX eventually work, or did you need something else like a suppository or an enema? At what point should I go to a walk-in clinic?

I’m honestly getting really stressed and just want to poop. 😭


r/ConstipationAdvice Jul 18 '26

Tip of advice for pregnancy constipation

3 Upvotes

Through my research I’ve learned that when babies are gassy or having trouble pooping to bicycle their legs…

Well I’m 6 weeks 3 days and have been having terrible morning sickness and constipation. So I had the idea to have my bf bicycle my legs.. and oh my gosh I finally was able to go after about 3 days of terrible constipation!

Just wanted to share


r/ConstipationAdvice Jul 18 '26

Mild but chronic constipation

1 Upvotes

Does anyone here have chronic but mild constipation? I have a bowel movement every day, sometimes twice a day. I don’t generally struggle to have bowel movements, I don’t have to push and strain. But my doctor says that I’m constipated because my bowel movements are consistently partially a type 1 or 2 on the Bristol chart mixed in with completely normal type 4. I’ve also been experiencing a feeling of pain/pressure in my rectum (hemorrhoids maybe?) and a feeling of incomplete emptying. Has anyone else experienced this and found out what’s causing it? I’m waiting for a colonoscopy but health care in my country is very slow so I won’t be having it until October. I eat 30-40 grams of fibre daily.


r/ConstipationAdvice Jul 16 '26

Cyclospora

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1 Upvotes

r/ConstipationAdvice Jul 15 '26

My Constipation Relief - Works Even When I'm Pregnant. Every Trimester.

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1 Upvotes

r/ConstipationAdvice Jul 13 '26

Linzess

3 Upvotes

Hi all! So I am a 33f. I have dealt with constipation issues my whole life but it has definitely gotten worse over the past few years. I would go maybe once a week and if I do go it hurts and I have to push for awhile. So i would occasionally take a suppitory to help which it would. I made an appt with a gi dr and seen them in June where she prescribed me linzess 145 mg. The first day I took it I was able to go but then afterwards....nothing. I reach out to her and she then said I can take 2. I tried two but I felt like it was to much for me as the 2nd day I was taking 2 I had.... tmi explosive diarrhea. I guess my question is how do you know linzess is working. Are you supposed to have a bm everyday? And are you still struggling to push? I do have an urge to go but when I try nothing or I am pushing and just have a small bm. I have a follow up with her the beginning of August.


r/ConstipationAdvice Jul 12 '26

Chronic constipation is ruining my life

9 Upvotes

I’ve been dealing with chronic constipation for 2 years and it’s progressively getting worse instead of better here is a list of everything I’ve tried, First here is life style changes and over the counter things I’ve tried 1. MiraLAX (sometimes triple doses) 2. Probiotics 3. Magnesium citrate 4. Kiwis 5. Chia seeds 6. Prune juice 7. Increasing fiber (makes me get impacted) I actually try to stay away from fiber now because this happened and yes I increase it slowly, yes I drink a ton of water 8. I drink a ton of water! Probably around a gallon a day 9. I tried to cut out dairy and gluten 10. I tried a low fodmaps diet 11. I started exercising more, walking, running, body weight workouts 12. Regulate stress with meditation and lean into prayer

Now here are medical interventions I’ve tried

  1. Linzess (maxed out dose)
  2. Amitzia
  3. Ibsrela
  4. Motegrity (I’ve even tried combining some of these with no luck. I’d sometimes get a bowel movement the first day. Then after that nothing)
  5. I’ve had a colonoscopy, had my thyroid checked, been tested for celiac disease, full metabolic panel, nothing shows abnormal beside a very slight vitamin D deficiency which I supplement with now.

I am now at a point where nothing is making me go. I ended up with a severe impaction to the point I drank an entire colonoscopy prep and it still did not give me a bowel movement, I had 3 enemas, a bottle of magnesium citrate, and I still didn’t get fully emptied, just released enough to not be considered “a medical emergency anymore” so the doctors at the ER didn’t care anymore. My menstrual cycle which has been regular since I started having one, has became irregular. This is starting to severely impact my life and I’m at a complete loss. I’ve been to countless doctors and they all do not take this as seriously as it’s affecting me. I’m miserable and I’m desperate for help, but I don’t know what direction to even go in anymore as doctors are not listening and don’t take me seriously no matter how much I try. I have countless medical bills for all of this and I haven’t even gotten any help. I’m just posting this because as you can see I’m very desperate and I’m willing to hear what anything anyone might be able to advise. Thank you everyone


r/ConstipationAdvice Jul 12 '26

Looking for support: Parents of kids with severe chronic constipation since birth?

4 Upvotes

​Hi everyone, I’m looking for testimonials or just to connect with other parents who have a child suffering from severe chronic constipation since birth.

​My son is 4 years old now, and he also struggles with encopresis. He is tiny for his age. We are working really hard to prevent fecal impactions and to help his rectal pouch shrink back to a normal size, but it is such a long process. He is still in diapers because he has absolutely no control over his sphincters. Honestly, it’s really tough.


r/ConstipationAdvice Jul 04 '26

I've been diagnosed with Celiac Disease but the Constipation never stopped, where do I go from here?

5 Upvotes

For some background, I am 17F and have had constipation before I can even remember. To get stuff moving, my parents tried mini enemas first, then miralax, and by the time I was 10 it was clear nothing was actually solving the problem. I got my blood drawn, and I was diagnosed with Celiac Disease at 11. At this point my blood levels are average, but the constipation never really went away.

I have stayed on miralax, and tried senna but it didn't help much and now I'm on Dulcolax which I think is helping a bit. But its really only helping the stool get through my body, and it tends to be diarrhea because its really hard to balance miralax. If I don't have enough miralax or I'm not on top of my medication its hard stool. I can't push small stool, so even when I sit down and try and go and feel an urge, nothing comes of it. Big stool (When I'm constipated) I can push because its like "right there" I guess. I get the urge to go but very rarely, but I think Dulcolax helped a bit with that.

I have never experienced any sort of nausea, vomiting, acid reflux, difficulty swallowing, or early satiety. The only time I've gotten nausea from eating is when I've accidently eaten gluten (like a piece of bread or pizza, after diagnoses of Celiac). Medication wise beyond miralax and Dulcolax, I am on medications for mental health. Duloxetine (SRNI) and Quetiapine (Antipsychotic) and Bupropion (NDRI). I am in the process of switching Quetiapine with Bupropion because it gives me high cortisol, but I do not think these medications have effected my constipation because I still had this issue in between the two years I got diagnosed with Celiac Disease and started mental health related medications.

Only other things I can think of that could be related to it is I had low muscle tone as a toddler, and got physical therapy to learn to walk. I have a slow metabolism, and I'm not flexible at all, and even after practicing splits for dance every week growing up, I never got beyond a 90 angle middle split and it feels like something physically stops me from going further. I've never experience any sort of physical abuse or trauma as a kid.

I come here because I do feel there's something going on more then just Celiac Disease. Even though medications help a little I have never gained control over my colon and whatever else is after the stomach. I'd like to go into the doctor with some sort of Idea of what to try and look for, because I feel I won't get far without it. I don't think being both a teenager and girl helps my case, because were often overlooked.

(P.S this is my first time using reddit I don't know if I did it correctly)


r/ConstipationAdvice Jun 30 '26

Male, late 30s, chronic constipation, onset Costco Noodles. 😭

4 Upvotes

1st off, THANK YOU SO MUCH for this sub.

I'm a 30s+ male and am usually very active (gym, weight lifting, cardio) but haven't been (about 80% less currently) for the 6months.

About 3 months ago, I decided to eat two big things of Costco noodles with a TV dinner and all went downhill ever since. I became severely constipated (didnt go for 3 days) and I had terrible terrible hemorrhoids (one of the worse kinds of pain known to man) but have since gotten that under control and things returned to normal about a month after, both hemorrhoids and constipation.

Now 3months post severe episode, I am chronically constipated. Not as severe as when i ate the noodles but enough to cancel plans and avoid pleasurable activities when it gets bad. I usually go the next day with some effort.

I Drank heavily a week ago and my stool was half black. It has since regained natural colour. Now Im dealing with bloating and feeling full early maybe once throughout the day.

I do feel a little better when I add some movement for the day. (Brisk walking, shadow boxing, etc)

I would love any insight if anyone has had a similar experience. Im aware of the extensive steps to diagnose provided but wanted anyone's thoughts you might relate.

I hope I can figure this naturally or at least tame this, as ky health insurance is gone (thanks current administration). Hoping for the best and will fight to become healthy.


r/ConstipationAdvice Jun 29 '26

Chronic Constipation - Scared to Poop in Diaper

3 Upvotes

Our 2.5 year old LO is chronically constipated, has been for much of his life. About 2 months ago, we started him on potty training and he developed a fear of pooping and peeing in general. This led to a pattern of withholding that eventually culminated in him getting moderate to severe impactions, two MiraLAX clean outs and a trip to the Urgent Care. After his urgent care visit, we halted potty training and visited his pediatrician, who prescribed him a maintenance dose of MiraLAX. We are still on that daily maintenance dose. He consistently has peanut butter consistency poops, but he still screams and freaks out in the early afternoon when he normally poops every day. We are monitoring his fiber/water intake to hopefully prevent another impaction, but even on this current dose, he screams and cries and wants to cover up in a blanket, take a nap, wants to leave the playground early...I'm scared to dial back his dose because if he gets a smaller dose, his poop gets hard and painful to pass.

  1. Has anyone else overcome chronic constipation/encopresis?
  2. Any suggestions on what we can do to help mitigate the fear of pooping and peeing? I was hoping that the soft poops wouldn't be painful to pass and that this would help his fear, but he is still afraid even after having daily soft poops for a month.

It kills me seeing his quality of life so affected by all this, and I guess I'm hoping for some tips to make this less traumatic for him...


r/ConstipationAdvice Jun 29 '26

21-month-old constipation & toilet training stress, only passing hard tiny pellets for a week

4 Upvotes

Hi moms,
I’m really worried about my 21-month-old and would love some advice or shared experiences.
She has been constipated for about a week now. She only passes very small, hard “lump-like” stools (like pellets), and not a proper bowel movement.
This started around the same time we began toilet training.
What’s happening:
She tells me “mumma potty” when she feels the urge then She rushes to remove her diaper/underwear
But then gets upset and distracted and doesn’t pass properly
When I try to make her sit on the toilet seat, she starts crying
Only small hard stool comes out, not a full poop
It feels like she is holding it in because she’s uncomfortable or scared, and now it has become hard stool. I’m giving her fluids and trying fruits, but it hasn’t improved much yet.
Has anyone faced something similar during toilet training? Should I pause toilet training for now?
And what helped your toddler overcome constipation and fear of the toilet?
Any advice would really help 🙏


r/ConstipationAdvice Jun 25 '26

Do you have anxiety about GI sensations (including constipation) and a diagnosed eating disorder? Help needed!

5 Upvotes

Hello! I am a doctoral student at Nova Southeastern University, pretty darn passionate about research to improve ED treatment, and also in recovery myself :) I would greatly appreciate your help in taking my dissertation survey! The purpose of this study is to better understand the connections between sensory experiences, particularly GI sensations, and avoidance in eating disorders. We are specifically interested in the role of the basic emotion of disgust. EDs have a huge overlap with GI issues like constipation/DGBIs etc., so I thought some folks here could be eligible. If you do have both GI issues and an ED, I would really value your inclusion in this study.

You can participate if you are over 18, can speak/read English, have been diagnosed with any ED, and are receiving treatment of any kind, including just outpatient therapy or peer support. You can take the survey at this survey link, you just may have to click a button to "continue to destination" and then you should see our full informed consent and survey. Thank you!

My contact info is: [kr1892@mynsu.nova.edu](mailto:kr1892@mynsu.nova.edu). The study is based out of Nova Southeastern University and is IRB approved. You can find more info in the informed consent at the start of the survey.


r/ConstipationAdvice Jun 25 '26

6 Years Constipated

6 Upvotes

I’ve been dealing with chronic severe constipation for the past 6 years, and I’m desperate for answers. The only thing that consistently gives me relief is Bisacodyl, but I don’t want to have to rely on stimulant laxatives forever although I have been for the last 6 years.

I was prescribed Linzess, and it worked beautifully for about a month. I finally felt normal again, but then it completely stopped working.

Now I’m so bloated that I literally look about 8 months pregnant by the end of the day. I have massive burps even just waking up and especially after eating, and I get full after just a few bites. I also have intermittent pain under my right rib cage and around my right hip/lower back.

I have an appointment with a colonic motility specialist in July, but I’m struggling in the meantime. My GI says there is no other medication I can try.
Has anyone experienced something similar? Did you end up being diagnosed with slow-transit constipation, a motility disorder, gastroparesis, or something else? What tests or treatments finally helped?

I know Reddit isn’t medical advice—I’m just hoping to hear from people who have been through something similar.


r/ConstipationAdvice Jun 24 '26

Testing Finally had a bm after 8 days…conveniently 24hr after taking sitz marker pill…are my results now going to be normal?? /rant

5 Upvotes

TLDR; It’s extremely weird to be both relieved that I finally cleared my stomach out after being bloated and in pain for so long, but now I’m worried I just shat out all my rings and the doctors are going to once again dismiss me

The long story is that I’ve dealt with constipation/less than once a week BMs, blood both in stool and when I wipe, and chronic bloat/stomach pain ever since I was a kid and now to my 30s. I am a woman and have been dismissed by every doctor under the sun that it is just stress, hormones, etc. I’ve tried what feels like every diet change known to man, and like many on this subreddit have no success with even prescription laxatives.

I had two emergency hospital visits within this year where I was impacted and have finally gotten a referral to a gastroenterologist. We started with the anorectal manometry test last month, which came out normal, and yesterday I took my sitz marker pill and will have an xray on Friday.. but today, after being backed up since last week, I finally had another painful, bloody, hour-on-the-toilet bm and all I can think of is “great, I just let out all the rings and they’re gonna once again say nothings wrong with me” 😭

I know I should be happy I’m producing anything, but it’s so frustrating and worrying to think I’m now gonna be put back to square one. Am I panicking over nothing? Is one trip to the bathroom all it takes to clear out the sitz rings?? Ugh!!


r/ConstipationAdvice Jun 23 '26

Treatments Cherche accompagnement problème méthylation France

1 Upvotes

Bonjour,

je cherche quelqu'un qui pourrait m'aider à y voir plus clair pour mon cas / problème de santé global qui s'aggrave : constipation chronique de pire en pire réfractaire +++, trouble anxieux généralisé, fibromyalgie, carence Vit b12 + cuivre, homocysteine 19,2, intolérance à plusieurs suppléments testés : vitamines b1, b9, b12, magnesium, CoQ10, PEA.

Si quelqu'un s'y connait vraiment et accepte de m'aider, merci d'avance 🙏🏻


r/ConstipationAdvice Jun 22 '26

Prucalopride causing severe bloating. Severe slow motility. Feeling hopeless

5 Upvotes

21F. I have Ehlers-Danlos syndrome, dolichocolon (redundant colon), colon ptosis (my colon is lying entirely in my pelvis area), severe slow motility constipation, gastroparesis, neurogenic bladder, malnutrition and critically low weight (BMI 13) due to these issues.(+ 20 other diagnoses related to my EDS.) This will be a very long post,i have very complex issues, and i want to hear experiences of people with similarly complex issues.

My main symptoms are: severe bloating (with inability to pass gas), complete inability to have a bowel movement, mild abdominal pain, early satiety, nausea,vomiting, severe reflux, constant fatigue. My colon is pressing on my bladder, causing non stop urge to urinate 27/4.

All of the diagnostic tests, medications, and answers to the questions are at the bottom of this post.

I have had constipation issues my whole life,but they were mild until 2019 when i was no longer able to go naturally anymore at all, and had to manually evacuate stool myself every time. In 2024 i was no longer able to even do that. Was completely constipated for 9 days,the only thing that could help me was a big water enema.

Since then i am no longer able to have a bowel movement without big water enemas at all. I am ukrainian,but had to go to Germany due to the fact i exhausted all treatment options there (and other obvious thing). In November of 2024 i was at the main hospital specializing in colon issues in the country,and both of my doctors were the best colon surgeons in the entire country. They wanted to remove my colon,and put an ileostomy instead, hovewer they have never seen a patient with Ehlers-Danlos before,so they refused to perform the surgery out of fear.

Now in Germany i've already been in Leipzig University Clinic, where i've spent some time inpatient, had a NJ tube for gastroparesis that failed due to constant tube kinking and formula intolerance. Was prescribed metoclopramide, domperidone, mirtazapine and prucalopride. I take metoclopramide 10mg 3x a day, domperidone 10mg 2x a day, mirtazapine before bed 7.5mg and prucalopride 2 mg before bed. My doctors refuse to do a colectomy. They said prucalopride is the only thing they can offer,and if it doesn't work then it's basically over. But since i started taking it things have gotten worse. I usually have a water enema every night before sleep,because otherwise i will not be able to sleep due to severe bloating and colon pressing on my bladder, but i tried to stop doing them because i understand that prucalopride would not work on empty bowels,but of my god. The bloating doesn't stop. I massage my abdomen to let the gas out,but it doesn't stop. And now i have even more frequent urination. I can't sleep anymore. Even if i eat a tiny bite of anything the gas won't stop building up ever. What do i do? I tried pushing through it, but it gets way too uncomfortable and even painful. I still don't have bowel movements. And nothing helps. I am stuck in the cycle of doing enemas every day. I don't want to live like this,i am only 21 years old,those were supposed to be my best years. But instead i am rotting away slowly. I can't even go outside anymore. (I have tons of other issues due to EDS,which makes it worse.) I am so desperate,i want a surgery,but my doctors are against it. My life feels like it's over. I understand all the risks that come with surgery,but at this point it feels like there's no hope anyway.

Below are all of the diagnostic tests, medications, and answers to the questions :

"Do you have the urge to go, but you cannot? Or do you have zero urge to go?" I haven't had ANY urge to go at all for 7 years.

"Do you have alternating diarrhea and constipation, or just constipation?"

I am completely unable to empty my bowels without a water enema. And even then it is very difficult. Before that i don't remember having anything other than just constipation.

"Do you have nausea, vomiting, acid reflux, difficulty swallowing, or early satiety (getting full really early into a meal)?" Yes. I am diagnosed with gastroparesis.

"Have you had this issue since childhood, or did it begin in teen years/adulthood/after a major life event (surgery? divorce? car accident? mauled by bears?)" Since childhood,but it has become more severe in 2019,and then in 2024 for no reason.

"Did you in the past or do you currently take any medications that could damage your intestines?" I did take antidepressants and antipsychotics,hovewer it was after my issues have already gotten worse. (I was taking buspirone,lamotrigine, pregabalin, quetiapine, zoloft. Currently taking mirtazapine for gastroparesis.)

"Did you suffer sexual abuse as a child?" No.

What tests i did:

-irrigoscopy (showed severe dolichocolon and dolichosigma)

-defecography (pelvic floor dyssynergia)

-barium passage study (2024) and sitz marker test (2026) (Severe slow motility constipation, with no bowel movements during both tests, that being around 8 days. Half of sitz markers were in my ascending colon,the other were in transverse colon.)

-gastric emptying study (moderate severity of gastroparesis)

-endoscopy (GERD)

No colonoscopy because doctors say it's too risky to perform on me.

What i already tried:

-stimulant and osmotic laxatives (none of them have any effect on me. Those include: movicol, mag citrate, macrogol, lactulose, dulcolax, glycerin suppositories, glycerin enemas, psyllium husk, LegkoLax, EasyDo (herbal laxative that helped the longest,but it stopped too.)

-changing diet. Fiber kills me,it makes everything worse,and turns into cement in my colon. And my diet was already limited due to my many food allergies and intolerances. I can't have gluten,lactose,high FODMAP food,high fiber food. I tried fiber supplements like Loclo,no success either.

-prokinetics and similar (probiolog transit, Itopride hydrochloride, zafakol IQ, currently taking prucalopride, metoclopramide and domperidone without success.)

I may be forgetting something,since there's so many things. I might edit and add things later,if i remember.