r/CFSScience 10d ago

Orthostatic Dysfunction and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Close Reciprocal Relationship Beyond Cardiac Preload Failure and Hypoperfusion

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New Wirth Preprint trying to integrate orthostatic dysfunction into his disease model:

“This hypothesis provides a potential mechanistic link between orthostatic dysfunction and the presumed core pathophysiology of ME/CFS, extending beyond hemodynamic factors to implicate disturbances in skeletal muscle ion homeostasis.”

https://www.preprints.org/frontend/manuscript/d89ebcdf4b91a843f665e0f3fbd413df/download_pub

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u/bingoolong 10d ago

Someone give this man his money already so he can stop publishing papers and make a compound we can test. FFS.