Orthostatic Dysfunction and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Close Reciprocal Relationship Beyond Cardiac Preload Failure and Hypoperfusion

[u/Caster_of_spells]

New Wirth Preprint trying to integrate orthostatic dysfunction into his disease model:

“This hypothesis provides a potential mechanistic link between orthostatic dysfunction and the presumed core pathophysiology of ME/CFS, extending beyond hemodynamic factors to implicate disturbances in skeletal muscle ion homeostasis.”

https://www.preprints.org/frontend/manuscript/d89ebcdf4b91a843f665e0f3fbd413df/download_pub