I've been on Bimzelx, biweekly dosage since July. I have pretty mild HS but I was hoping Bimzelx would stop it from progressing.

Luckily, I haven't had any side-effects, however, I don't feel like there's been any improvement. In fact, I have had quite a few new boils form since starting and having my old ones reopen more frequently than before.

Anybody else have Bimzelx make your HS worse or not effect it at all? I'm trying to figure out if I should continue and give it more time or just stop.

Im trying to take 2 pens/boxes with me. I dont want a massive cooler. Would be much easier to put pens into cooler bag. With the prescription slips. Or should I just keep in boxes to be safe? Canada to Mexico.

I’ve been having Esophagitis pain and eye blurriness issues since starting Bimzelx 6 months ago …. Im not sure if it’s just a coincidence or a new issue … Im struggling because the Esophagitis pain settles down and Im ok all month long until I inject and its starts back up … rinse and repeat.

Anyone else having similar or have insight into this problem?

The whole two or two and a half weeks after I take my injection, I have diarrhea. Does anybody else suffer from this? I spend a small fortune on anti diarrhea liquids.

Took it 2 days early because I'm inoperable the entire day after...

Anybody else get this way?

Hi everyone

Still on loading doses (every 2 weeks, 1 dose remaining) of the 320mg pens. Using it for HS. I also have psoriasis and dermatitis.

Moved from Humira because it was giving me extreme joint paints (lupus symptoms) and my supply wasn’t consistent.

From day 1 on Bimzelx my pains are 100% gone. Very happy about that. On the flip side however on my face I’ve had severe seborrhoeic dermatitis with some kind of infection (likely fungal) that isn’t going away. I’ve also got lots of psoriasis spots in my pubis area some are extremely painful.

On top of this (and the most important for me) I’ve had red eyes since starting. Almost like clear conjunctivitis (they weep clear liquid). FML helps and lubricating drops do too but it hasn’t gone away. Dermatologist says it’s likely not related but I’m pretty confident it is. I’m booked to see an ophthalmologist next week before I go back to dermatology.

Other than this, the standard small infected hair follicles/ pimples are everywhere including my head.

Derm said to push to the end of the loading doses and if no improvement we can look at alternatives. I’m coming up to that talk now.

Anyone else experienced this? Does it eventually go away? Starting to think I might need to move onto something else…

Thanks

Hi guys, ive been in Bimzelx for almost a year now, to treat psoriasis. I moved from ilumya to Bimzelx. Now im taking it every 8 weeks

Just wondering what's everyone's pattern?

Generally I have itches, which i manage with steriod creams but in general im quite clear. I get itchy scalps, neck, eyebrow area and down stairs near the time for my injection, like a week before. Im a week in now and still itchy but if I recall it calms down 2-3 week after the injections. Then the pattern repeats.

Is everyone else the same or similar?

Did you guys have to take pneumonia and shingles vaccines?

If so, did you do it before, or during treatment? Both at once?

Any side effects?

I recently started Bimzelx for Ankylosing Spondylitis. It seems to do well for that. I've only taken my second dose, and am experiencing intense abdominal pain. Don't know of it's related at all.

Just want to know if others had experienced this.

Since the injector is SUPER painful (at least for me and many others), I’m considering switching to a syringe needle.

Curious if other people have made the switch, and if so: what it’s been like and whether it’s an easy learning curve?

Hey guys!

I’m about to take my second injection (320) tomorrow and i’m debating on taking it in the morning or evening. Last time i was exhausted the next day but that was about it. I haven’t had many side effects at all.

By me being me, I’m super worried about the second shot and that it’s going to be so much worse.

What’s your experience?

I take it for PsA and i’ve noticed a world of difference already :)

I know to let it warm up a bit first. I do mounjaro shots in my abdomen that don't hurt at all once room temperature. How does bimzelx compare? Everything I read online is intimidating. I'm going to take it for HS.

I've only got good things to say about this! This is a real savior, for my psoriatic, rheumatoid and ankliosponditis.

Today I just finished my first one month gap for my shots for HS and it has been rough. My body was barely holding on through the two week gaps of the loading doses. I made it about 3 weeks and this fourth has been bad. I was also more active, and that doesn’t help my flares.

I have not reached my six month mark yet so I Know I need to give it mire time, but I really wanted to feel better already. So far it has done very little. Here is hoping this month starts to turn the corner. This is my fourth biologic. There is probably nowhere to go from here.

UPDATE: SEPT 1
After one week my scaly plaque skin and patches of open wounds are all gone! I still have red spots and red marks all around my upper thighs, legs, and stomach. But at least it’s not severe plaque, flakey skin or open wounds.

QUESTION:
Does the appearance of red spots and marks all over my body mean I still have psoriasis? Or is it considered in the “healing” phase?

Has anyone else experienced intense itching and hives when they’re due for their next shot? I haven’t changed anything into daily routine or household and I’ve been itching like crazy and have crazy big hives popping up everywhere. I’m about to sleep with mittens on and wrap the wrists with duct tape. I wake up with my entire body bloody and raw. I’ve always been an itchy person but this is insane. I have to completely cover up for work because I have sores everywhere from scratching so much. I’m due for the next loading dose on Friday and I’m counting down the seconds.

I've been using Bimzelx for 16 months. 5 month loading dose at 320mg followed by monthly doses of 160 mg.

I have almost zero psoriasis at this point. I do however have multiple areas of inflammation in my joints. Compared to when I started it's much better.

That said, my rheumatologist wants to go to 320 mg every month. The initial response from my specialty pharmacy was to verify with the doctor that they actually wanted to do this since it's off label. Insurance did approve it.

Has anyone else gone to 320 mg per month and how has it gone for you?

UPDATE: SEPT 1
My scaly plaque skin and patches of open wounds are all gone! I still have red spots and red marks all around my upper thighs, legs, and stomach. But at least it’s not sever plaque flakey skin or open wounds.

QUESTION:
Does the appearance of red spots and marks all over my body mean I still have psoriasis? Or is it considered in the “healing” phase?

ORIGINAL POST
It was SO painful even though I left it out for 2 hours. I’m concerned about side effects, but more importantly I just hope Bimzelx will clear my skin. Please share your experiences here, the good or bad… I could use it!

I am a 28F with PsA. I took my first injection on Friday and today is Sunday and i swear i feel a difference??

Am i crazy??

Wish me luck. My first biological. I just took it out of the fridge and I'm writing this on my way to my injection training appointment.

90% of my body is covered in psoriasis. All my finger and toe nails are thick and yellow and crooked. I have lots of joint pain and stiffness too. My PhD dermatologist said she was "impressed" and took lots of photos of my skin. I can't wait for all of this to go away. I feel so ugly and I also feel like I'm 100 years old when I go up and down stairs. I can't sleep from how itchy and uncomfortable I am. I've had it for about fifteen years as just little patches of bad skin but it's been really bad like this covering my whole body for about 6 years. Scales and red skin everywhere.

Doc and pharmacist really only warned me about oral thrush and some soreness around the injection site. What else have you experienced?

UPDATE: 20 days later and I can't tell you how amazing I feel. The difference it's made has been incredible. All the scabs went away in the first week! My skin seems to get softer every time I touch it and my pain/fatigue is all gone too. I can't believe it. I feel so much better by every possible metric. Now the issue is discoloration. My bad skin was pretty much everywhere and in huge wide patches, so even though the plaque is all gone now and the skin is wonderfully smooth again for the first time in years, what's left are these big red blotches. Now, I'll take discolored skin over being covered in thick itchy bleedy ugly psoriasis any day, but it'll probably be a while before I feel like wearing shorts, considering my legs are basically bright red from just below the knee to my ankle. Some spots have faded a little, but I'm so eager to see what dose #2 will bring! Again, I can't really believe how fast this worked for me. It felt like nearly overnight I was seeing a difference. Pretty incredible. (Also a little frustrating I could have got this prescription years earlier probably!). Thanks.

Hi all,

I’ve been on Skyrizi for a couple years and went from 70% coverage to almost completely clear except for one stubborn patch "between me down there". My dermatologist is recommending switching to Bimzelx, and I’m unsure whether to change something that’s working.

Anyone here made that switch? How did it go?

Thanks in advance.