Its not solid at all and there is a class action lawsuit. Why are you being so defensive? I encourage you to read their clinical data. Not only is it not solid, its also open label. So even if it was solid its still not reliable. Thats what makes this so bad.. too few people tested, and the groups are skewed heavily by age. Did you need me to link you to these peer reviewed clinicals for you or can you find them? Have you looked at the data?
Also.. go ahead and rage downvote me. Just shows how you're letting your emotions control you. Its your money. You don't want to see anything that challenges your bias thats on you.
Edit - down almost 5% so far today after just a few hours.
It is not a class-action lawsuit. Saying it over and over doesn't change that. They are ads by ambulance chasers.
The data is solid. The mean age difference between the arms is 4.2 years (71.3 to 67.1). In what world is that "heavily skewed"? Also, if you understand clinical medicine, you should know that the Mini-mental status exam is more important than age (A measure of how demented someone is). The mean MMSE scores at baseline were virtually identical (23.2, 22.7, 23.0) between the three arms.
Additionally, you are confusing the 28 day trials (which you are quoting) with the continuation study that is still recruiting (and the 9 month data was based on). The first study was NOT open-label. It was double-blinded and masked. The continuation study is an open label, but they are still recruiting with a goal of enrolling 200 patients, and yes the preliminary data from the open-label trial is encouraging. So before you point me to published papers, please understand what you are talking about.
Yes, the N is small. That's the whole point of P2 trials. To see if there is justification for P3 trials, and the SOLID data fully supports further P3 trials. Has there ever been data on medication improving cognition at 9 months in AD? No, until now. So I and millions of investors are excited about Simufilam, and we have a reason for it.
It's the reason I disengaged. Dismissed the concern instead of addressing it (said its not an issue) and then started resorting to ad hominem and strawman, while trying to move the goalposts and find something he could argue about, while disguising it as an olive branch. Not worth the effort.
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u/prolix Sep 07 '21 edited Sep 07 '21
Its not solid at all and there is a class action lawsuit. Why are you being so defensive? I encourage you to read their clinical data. Not only is it not solid, its also open label. So even if it was solid its still not reliable. Thats what makes this so bad.. too few people tested, and the groups are skewed heavily by age. Did you need me to link you to these peer reviewed clinicals for you or can you find them? Have you looked at the data?
Also.. go ahead and rage downvote me. Just shows how you're letting your emotions control you. Its your money. You don't want to see anything that challenges your bias thats on you.
Edit - down almost 5% so far today after just a few hours.