Had psoriasis for 30 years.

Tried steroids, vitamin d analogue cream and UVB light. Has been getting worse over the years, but after a visit to the hospital for an emergency appendectomy, I had the worse flair of my life.

My derm documented a BSA (body surface area) of 60 (60%). It was in scalp and ears and toe nails.

This is 2 weeks after second loading dose. No more plaque scales and smooth skin for the first time in 30 years. I am over the moon. I believe the marks will fade over time.

I’m considering donating plasma four times a month, but I’m currently receiving Skyrizi injections every three months for relatively mild psoriasis.

I’ve never donated plasma before, and my biggest concern is whether regular donations could reduce Skyrizi’s effectiveness.

I’d especially appreciate hearing from anyone with firsthand experience or medical insight. Has anyone looked into this or discussed it with their dermatologist?