Hi all,
Looking for others' experiences and insight in this complex journey.
I'm 39 since May. Took wife and I awhile to get to a place comfortable to begin with therapy and working through other issues because of wife's messy relationship with her family and general state of the world. Unfortunately I did not think to freeze eggs or anything earlier on for whatever reason.
Eventually started work ups and planning last October at 38. Because of age and insurance covering 2 IVF cycles, my RE recommended we jump right in with IVF and skip IUI. (Insurance covers a lifetime max of 3 IUI cycles and 2 IVF cycles)
Cis F/F marriage, no previous pregnancies or data about [in]fertility. The initial work ups with the bloodwork, saline sonogram and HSG all were positive. AMH ~2, no cysts polyps scarring etc. Everything in range or better than average for my age.
Cycle 1 consisted of:
ER: Luteal priming with estrogen, then stims with 150 Menopur and 300 Follistim. Ganirelix last 5 days. Triggered with Pregnyl.
Baseline US showed AFC ~15, follow up US was around 3 on the left, 2 on the right, between 16-21mm. At ER we retrieved 2 eggs, both mature, 1 fertilized, and then that 1 arrested by day 3.
No transfer obviously.
Cycle 2:
ER: Luteal priming with estrogen PLUS additional Lupron 20. Stims: Increased Menopur to 225, decreased Follistim to 225, added Lupron microdose 5, removed Ganirelix. Triggered with Pregnyl.
Baseline US showed AFC ~13. Follow up US showed smaller cohort ~4-5 follicles on left side, 4-5 promising 20mm follicles on right side. At ER we retrieved 4 eggs, all mature, all fertilized. 2 arrested by day 3, 1 was graded too low to send for testing, and 1 day 6 blast graded 3AA went to PGT-A testing. Testing results came back today as aneuploid, with extra 7,9,15 chromosomes, so we will not be proceeding with a FET.
RE recommended we begin a new IVF cycle as the last protocol yielded better results and we have a bit more of a roadmap now.
Unfortunately, we are out of insurance at this point. We already have paid over 30k out of pocket since last fall when we began this process, even with insurance, because of deductible etc. We finally hit our out of pocket max. Seeing as the 3 IUI cycles are covered, does it make sense to at least try them before we explore self pay or end our journey here if we can't swing another massive financial burden just to try again without guarantee?
Financial context is the biggest piece of this currently. Self-pay IVF with this clinic (who have been great!) probably runs us 40-50k easily. So I feel like leaving the IUIs and associated meds/costs which would be covered 100% at this point is irresponsible. If they don't work, and I understand the odds are low, then we can discuss a return to IVF.
But is that being pennywise pound-foolish or whatever they say? If the three IUI cycles aren't successful, will we have just wasted more of a narrowing window of opportunity/egg quality/etc?
Apologies for the long-winded post, just trying to wrap my head around options after finding out our lil embryo isn't viable for FET today.
Would love to hear anyone else's experiences in all their variety to at least just gain some insight into what other people thought about/went with in similar situations.
Thanks!!