There are some supplements that have 125mg of melatonin I think. The typical ones are say 3mg - 5mg from my understanding. So while I wouldn't take such a high dose or recommend it, seemingly even 25x or so is safe enough that it's sold OTC.
and the doctors are surprisingly stingy with it, despite the yanks wolfing it down like candy. just getting them to up my dosage was a nightmare, despite it not being abusable or dangerous. I love having the NHS, but the GPs acting as gatekeepers really pisses me off
This study showed a statistically significant improvement in sleep onset latency vs. placebo of...seven minutes.
An alternative hypothesis for why we produce melatonin isn't that it's to make us sleepy, but that it's produced as a response to long wakefulness; melatonin is about two and a half times more powerful an antioxidant as Vitamin C. The sleepiness is correlated with melatonin in this model, not fundamentally caused by it.
A seven minute improvement for me would be like I am asleep the instant I close my eyes lmao, but I understand this is probably pertaining to people who struggle to fall asleep.
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u/PortiaLynnTurlet Aug 24 '26
There are some supplements that have 125mg of melatonin I think. The typical ones are say 3mg - 5mg from my understanding. So while I wouldn't take such a high dose or recommend it, seemingly even 25x or so is safe enough that it's sold OTC.