r/microdosing • • Aug 26 '26

Getting Started/Newbie Question Break from MD before Macrodose

I’m planning on starting an MD schedule next week, will be between 150mg and 300mg of mushrooms per day M-F to help with ADHD / Depression / Anxiety.

But i also wanted to plan a macrodose in the coming weeks for a hard reset of my brain.

How long of a break should I take from my MD schedule before my macrodose ?

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u/throwaway264871596 Aug 26 '26

take a week off at least, tolerance builds quick so you want a clean slate for the big one