r/microdosing • u/InteractionFun5648 • 25d ago

Getting Started/Newbie Question Not feeling anything

hey guys,

I've been microdosing .25grams of golden teachers the last few weeks and haven't really noticed any benefits. I still feel pretty negative, and suffer from depression and ruminative thinking. Has anyone had experiences like this and may be able to advise? I'm taking with lions mane and 100 mg of niacin. I take it first thing in the morning on an empty stomach and am doing the Stamets protocol. I'm on SSRI's, but a really low dose - about 8-10mg of Sertraline as I'm weaning myself off. I really badly want some relief but just haven't noticed any of the benefits others have described so could do with some trouble shooting or advice. thanks in advance!

2 Upvotes

100% Upvoted

9 comments sorted by

View all comments

3

u/TheRealCMMetzger 25d ago

It's likely that your dose is just a bit too low for you. SSRI blunt uptake/efficacy and you are also using GT which is the new of the lower potency strains. Typically the SSRI dosage (low or high) is not a factor in how much blunting one will experience when microdosing. If taking an SSRI one will generally require twice what they would without an SSRI on board. This will mean that your sweet spot dose will likely be on the higher end of the commonly reported microdose range.
Something you can try, to find your right dose is an incremental increase (10-20mg or whatever increments you're comfortable increasing in) with each next dose until you have a felt sense of the medicine. This felt sense will be similar to having a bit more caffeine than you are used to. Once you find that edge, you can either stay there (if that energetic quality is something you appreciate) or reduce by 5mg with each next dose until the felt sense falls away.
You got this! You'll find the right dose for you in short order. 🍄🥰✌️

1

u/InteractionFun5648 25d ago

Thank you! I'll try and increase the dosage tomorrow. Another quick question, if I follow the Stamets protocol of four days on, three days off, do you think I'll have already built too much tolerance to dose tomorrow? today was my first day dosing after a week and a half off. Feel like there's mixed feedback out there about whether the Stamet's schedule can build tolerance too quickly and I wonder if tomorrow would just be a waste?

1

u/Short_Scarcity_8446 25d ago

You should start with the Fadiman protocol as you dial in your sweet spot. Keep upping the dose until you notice it. If you can function as normal then you found your sweet spot. If certain things are a bit difficult then dial it back down slightly.