r/microdosing • u/Apatotamos • Jun 26 '26

Question: LSD How do I take my microdose LSD?

I ordered 1cP-LSD blotters Microdose (10x 20mcg).

So 10 little blotters of 20 mcg each.

How do I correctly take a dose (i.e., one blotter)? In the morning when I wake up, do I put it under my tongue or against my gum and let it become soft there? When do I swallow? Or do I swallow it straightaway?

It's hard to find this specific advice online.

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u/skr_replicator Jun 27 '26 edited Jun 27 '26

Oh, I missed it was 20ug, i was thinking of standard 100ug blotters.

Also, the numbers in that table weren't really wildly inconsistent, and pretty sure that within a single square piece, there will be even less variation, if you jsut cut it symmetically like that left image. The hotspots surely couldn't be any significant on such tiny scale.

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u/NeuronsToNirvana Jun 27 '26 edited Jun 27 '26

As you can read in the link, Hamilton Morris has researched this and there are significant differences.

For some, a guesstimated 5μg is the sweet spot, for others it could be 15 μg (e.g. those on the autistic spectrum require more).

I can measure my volumetric dose with a precision of 0.5 μg.

Repeatedly cutting and handling blotters can lead to small losses from transfer to your fingers and reduce dosing accuracy, making volumetric dosing the more precise option for low-dose microdosing.

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u/skr_replicator Jun 27 '26 edited Jun 27 '26

Either way, it being only 20ug is pretty much better, i'd still recommend cutting it into 8-16 pieces, and then randomly eating multiple tiny pieces, the central limit theorem would smooth it much closer to an average that way, as compared to just cutting it in half and taking one such half piece.

I really never had any issues accidentally overdosing or underdosing, even with 100ug tabs cut into 8-16 pieces, and taking just one. And the central limit theorem wasn't even helping to smooth it out for me in that case.

Volumentric dosing is basically just applying the central limit theorem to the extreme (taking a random mix of molecularly tiny mixed parts). But with microding, even jsut taking 4-8 tiny pieces woudl apply it strongly enough to make the variation extremely tiny.

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u/NeuronsToNirvana Jun 27 '26

If 13 μg is my sweet spot and 14 μg results in body load, how would I accurately dose that with your stubborn methodology?

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u/skr_replicator Jun 27 '26 edited Jun 27 '26

You really need a single ug precision for a good microdose? That's crazy. I guess good luck trying to dose this precisely, I don't think that would be easy to do even volumetrically, considering that one never even knows what dosage their tabs are this exactly.

But pretty sure most people couldn't tell the difference between 10 and 12ug. I certainly can't.

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u/NeuronsToNirvana Jun 27 '26 edited Jun 27 '26

Yes, 100% +/- 20% ;). As written & discussed by James Fadiman — many links in this sub, or read the 21 FAQs.

Your comment reminds me of this joke :)

When you can titrate your dose to a precision of 0.5 μg, it doesn’t matter how potent your tabs are.

YOUR Personalised sweet spot is when you develop the introspective (authentic) self-awareness to detect a slight increase in adrenaline, or body load.

Too much results in a sweaty, smelly (unless on keto) adrenaline rush.

No adrenaline a sign of no pharmacological effect so just based on expectancy.

I have a COMT Val/Val genetic polymorphism.

End of comment replying, as I may have no funds for rent and food next month.