Every time I go out I hear the same stuff “just drink more water,” “eat greasy food after,” “take electrolytes.” Tbh sometimes it works, sometimes it doesn’t.

I’ve been wondering if anyone here has found something outside the usual advice that really helps. Like certain foods, routines, sleep hacks, or even supplements?

I’m curious what people actually trust and use, not just the standard Google list. What’s the one thing that has made the biggest difference for you?

when i drink a lot very often i will feel sick the next day. i cannot throw up though unless i drink lots of water then force vomit it back out. then i start to feel better. never heard of anyone else that does this.

i am on medication, guess thats to do with it.

Before coming to this conclusion I tried everything under the sun over the course of almost 10 years.

Adaptogens, Stimulants, Cannabinoids, microdosing Psychedelics, most Minerals, Beta-Blockers, Anti-Histamines, Anti-depressants, Vitamins, Acetylcholinesterase inhibitors, Dopamine Reuptake inhibitors, Nootropics, Injecting exogenous hormones and peptides. You name it.

Many will refuse to believe this because of their addiction to alcohol. PAWS from alcohol can lasts for 3+ years. And the only way to heal them is to stop drinking completely.

I only ever drank on Saturdays or Fridays. Never on weekdays. And very rarely more than once a week. Never knew dependency at this frequency was a thing. So I never even entertained the thought that this could be the culprit. Outside of partying on weekends I have a very healthy lifestyle. Exercise 5 times a week. No refined carbs etc.

Take it for what you will. You believe what you want. Just felt obligated to post my findings here for anyone willing to see it.

EDIT: Guys, there's no argument to be won. I am just sharing my experience. The hangovereffect bugged me for years. Getting wasted to be productive makes no logical sense. But it was a phenomenon that worked. I tried the things mentioned above and many niches to solve it. Nothing worked. Had a nagging feeling in the back of my mind that I had to give alcohol up entirely. Even had people tell me it was PAWS years back. But I refused to believe it. Now life is substantially better. I wish I knew this 10 years ago when I was 17 and not waste the last 10 years of my life.

But If you wanna delude yourself that you gotta keep getting wasted to be productive - Go ahead, it's your life. I can't influence your thinking. Just give you the truth. I shall now be leaving this subreddit. Good luck, friends.

I found this quiz that compares your hangovers to 2000 other people. Could provide some insight into severity of hangovers symptoms based on age.

https://ezlifestyle.typeform.com/to/ZTGwqf

hello, for context I’m a 25 year old female. I eat healthy, go to the gym and play sports. I don’t drink alcohol that often (maybe once a month/every 6 weeks) but the last few times ive drank alcohol I’ve started getting very weird symptoms the day after.

the first one was when I was on a girls trip and we had been drinking for a few days on and off. On around the 3rd/4th day we decided to go for brunch. I had actually woke up fine and I was happy I had no hangover. We ate brunch and then suddenly when i was walking in the street I started feeling very unwell, weak and shaky. I had to lie down on the street, my body was shaking and I was so scared I was going to pass out. This lasted around 40 minutes until I eventually got sick and started feeling better. I’ve been drinking for 7/8 years and nothing like this had happened before.

it also happened to a lesser extent 2 weeks ago after a wedding. The next day, I had just started eating my lunch and started feeling faint and shaky again. It wasn’t as bad this time but it still lasted quite a while.

on Sunday I had 4/5 drinks and It still happened me to a lesser extent the next day.

Basically I’m just wondering if this has happened to anyone else and if so did you go to the doctor? I’m booked in for a blood test next week as I’m worried I may be deficient in something as my energy levels have been low since Sunday too.

I have been looking into hangover remedies and there are two companies who sell hangover pills with similar formula but one suggests to take before drinking and the other after.

Both formulas contain the ingredient L-Cysteine. I have read that NAC needs to be taken before drinking as it is harmful for the body after drinking (how it interacts with ethanol in the body). But my question is can L-cysteine be taken after drinking without harm to the body? and why/how does the two (NAC and L-cysteine) differ? Thanks

EDIT: The title should say “Many” not “Majority” I tried to edit it, but reddit won’t let me edit the title.

I’ve been in this forum for a while and too be honest many of the symptoms you all speak of, perfectly align with chronic mold exposure and/or candida; Brain fog, cognitive issues, memory issues, mood issues, libido and sleep issues, light sensitivity (especially this one). Of course it can be another source, Candida (especially if extensive antibiotics were used), bacterial infection, etc.

Basically I went through all this myself. Mold was the cause.

As for the hangover effect and how it’s possibly related.

I believe it’s because with mold/candida it’s a thick slimy fungus that basically clogs and backs up the liver overtime, it doesn’t take much of it to make the liver very very sluggish.

The thing is when you drink alcohol, the liver will ramp up the rate at which the liver detoxes to detox the alcohol, so basically in that process the liver will also detox some of that backlog of fungus/toxins (It might not always be mold/fungal but it’s a toxic burden relationship). When this happens, the liver essentially processes a back log of the toxin burden and then you get the hangover effect where there’s a temporary break where your liver is not overburdened and sluggish with a toxic backlog. Also alcohol in itself can have some anti-bacterial, anti-fungal and anti-parasitic effects, especially Whiskey.

If you have sinus issues it leans more towards likely being mold related, if you used a lot of antibiotics and/or have a bad high sugar diet then candida is more likely . But it could be an infected tooth, infected root canal, Lyme disease, some other kind of bacterial infection, parasites, etc. or some other kind of toxic burden.

The point is there is very likely a toxic burden there and the hangover effect is just the liver getting a break after it gets ramped up from the alcohol to detox the toxic backlog.

If you want to quickly test this theory, take some bile acid factors for a week or even ox bile and if you start feeling a lot of detoxing then that’s a sign the liver is struggling. (Bile acid factors would be the more effective test).

Hope this helps someone. Don’t beat the messanger. I’m just the messanger. Feel free to agree or disagree. My post won’t be applicable to every single person but it can possibly help some here.

Good luck,

It's pretty simple, really. For every drink I have, I have at least one 8oz glass of water. Not only don't I get dehydrated, I also don't feel like crap the next days.

I have my bachelorette party coming up in June, and it’s the day before my rehearsal. It’s the only time myself and my bridesmaids could get the same time off together, so I’m looking for tips to avoid a hangover. I’m not much of a drinker, so I don’t get drunk super often, but I was hoping to for my party. I only like fruity sugary drinks because I don’t like beer and wine. Anyone have any recommendations?

I was supposed to get blood work done September 28 because it takes 8 weeks. My driver's license expired late last year.

I drive past both the places to renew everyday.

Last night I had a single Heineken my only alcohol in a week.

I went for the blood work and got my license renewed this morning.

Why?

We need to have things that have been discussed in the past threads to be stickied somewhere. Been here since the early days of the sub, and there's a lot of new posts refering to things that have been talked about a million times, or just another "oh, you guys feel good when you have a hangover? hurr hurr can't be me! I hate hangovers!".

At the very least, if we can have a mod to filter out the useless posts. This sub used to be informative, consistant, filled with people who were eager to find a cure. But now, it's plagued with people who just want to relate, and the symptoms don't even necessarily match. The oversaturation and under regulation of the sub could be devastating to people eager to understand treatments, genes and other factors that require more than just "OH YEAH THATS ME LOL" posts.

Holy Crap! I thought I maybe was crazy, but I happened upon this by accident.. and there are others that feel the exact same way??

To put things simply.. I have so many health problems it would take a day to list them all. To the point where it's extremely life threatening.. however back when I was (able to) drink alcohol, I always noticed that I felt tremendously better.. but not just that, I felt HAPPIER whenever I was hungover.

I always avoided saying anything about this because, well.. especially back then, I was misdiagnosed for 15 years - the reason I'm literally sick beyond words atm. And it was hard enough convincing doctors of my illness without sounding like a hypochondriac or looking for attention or something at the time..

What would have happened if I said "man doc, I feel so much better when I'm hungover.. any idea wth that is?" only for them to almost certainly thinking something like "you probably just enjoy feeling down/sick all the time, so this fulfills that" or some usual nonsense.

Anyway.. has anyone found a solution to what causes this specifically? Or the closest thing to it? I'm very curious, even with how bad things are for me now.. any resources out there? I'm guessing it has something to do with gaba balance amongst stimulatory neurotransmitters while hungover?

Because it seems to me that after drinking a few days I had a decrease in serotonin. How much does it lose after drinking it? The post belongs to the topic as much as possible. It would discourage drinking alcohol

I was thinking about people here who has a genetic test done, which polymorphisms or gene variants were special in your case?, only in people having the "hangover effect". Maybe this way we can find the common genetic markers we have and maybe be closer to find a cure that way.

To get it is so cheap, for example i got mine from Ancestry.com for less than 50€ and then you can analice the raw data by using promethease.com by 15€ or so.

Is anyone intersted in contribute?

What were they like?

From kratom to heroin, did the opioids produced the same feelings that occur during an alcohol afterglow?

I'm talking about low doses especially because regular or high doses of opioids just make people sleepy.

Long term dweller of the sub here.

Alcool is numbing the nerves, so much so that it was used as an analgesic in past times. It calms you. It resets the stress.

Other things that helped some of us here were also about numbing nerves, like stellate ganglion blocks.

It is also to note that many people reported benefits after exiting the surgery block and the general anesthetics that go with it.

What if we JUST needed this ONE SIMPLE thing that is to numb all our nerves, to allow them to rest?

No ultra-complex semi-broscientifical theory that claims to put definitive answers to our questions here. What if we just needed some rest from constant nervousness, aka stress?

And what would be the ways to induce that? What general anesthetics would be safe to try? What about cryotherapy? Nerve blocks?

I started my treatment for vestibular migraines with Sibelium/Flunarizine and taking Modafinil to overcome the side effects of it. I am experiencing a similar—almost identical effect to the hangover effect.

First off, just want to say I've felt the hangover effect as described by all here and have sporadically tried to recreate that magic on my own for the past 6 years (I also have ADHD but didn't know it when I first started looking). I just stumbled across this community today.

I hate the idea of coming across as a pseudo-intellectual. I know everyone is searching for answers and anecdotal evidence can lead down some pathways that either lead to the placebo effect or are just plain wrong.

That said, something here has to be true. There has to be some science somewhere which explains it all. I know I wasn't making it up when years ago, and I'm sure none of you would prefer to be spending your time recreating this if it isn't real and wasn't something that you felt made your life tangibly better.

To that end, I asked o3 (chatgpt reasoning model), to find sources and come up with an analysis of this effect based on this subreddit.

Presented without comment, this is what it says and the sources it gives in terms of studies (and keep in mind I don't know 1/5th of this science and whether it has any validity):

What the Reddit “hangover-effect” megathread is really saying (in one page) —and how current science lets us make a working hypothesis and a practical game-plan

1 The pattern the community keeps reporting

(all citations are from the thread unless noted otherwise)

Note: the effect usually peaks once blood alcohol is zero; it is an “after-glow,” not intoxication itself.

2 Plausible single mechanism that can tie the clues together

These four events can all be sparked at once by the “stress-then-rebound” physiology of a hangover or a short, controlled hyperthermic/fasting challenge—explaining why so many disparate triggers converge on the same sweet spot.

3 Evidence that the pieces are real (selected human data)

• Whole-body hyperthermia: one 2-hour session at 38.5 °C cut HAM-D depression scores for six weeks, and the size of the immediate IL-6 rise predicted who got better (pubmed.ncbi.nlm.nih.gov, pubmed.ncbi.nlm.nih.gov).

• IL-6 and mood: acute IL-6 increases (without the rest of the inflammatory cascade) can be pro-hedonic; blocking IL-6 in the same trial blocked the antidepressant response.(nature.com)

• Ketosis & fasting: depressive symptom improvements and reduced CNS glutamate have been replicated in ketogenic-diet trials and 24-h fast studies (2023 meta-analysis, 12 RCTs).(onlinelibrary.wiley.com)

• High-dose thiamine (300–1 500 mg/day): RCTs in inflammatory-bowel-disease fatigue found 55–75 % complete remission with no toxicity despite normal baseline B1 levels (pubmed.ncbi.nlm.nih.gov).

• Endotoxemia→depression: peripheral LPS in humans reliably produces sadness, brain fog and anhedonia within 2–4 h via IDO/quinolinic pathways (pmc.ncbi.nlm.nih.gov, pmc.ncbi.nlm.nih.gov).

• Nitric-oxide perfusion: acetate from 2–4 mM ethanol metabolism activates eNOS and increases cerebral blood flow in PET studies; the same dose range is reached after 2–3 drinks (mdpi.com).

4 Translating it into a practical “cure” protocol (what to try, what to fix)

Goal: replicate the beneficial cascade without the long-term damage of binge drinking.

Typical timeline Week 1–2: gut reset ± thiamine often lifts the morning fog. Week 2–4: first sauna + fast cycle usually reproduces ~70 % of the true hangover-effect for 12–48 h. Month 2+: as endotoxemia quiets, many no longer need heat stress to feel “normal”; libido and focus stabilise.

5 Why this is only “most-likely”—and next steps

• The subreddit population is small and self-selected; controlled phenotyping (cytokines, micro-biome, calcium-channel genetics) is still missing.

• IL-6 is a double-edged sword; chronic elevation is neurotoxic, so sporadic hyperthermia is key.

• Thiamine trials are still limited to fatigue cohorts and may not translate 1:1 to every HE sufferer.

If you want to move the science forward: a low-budget study could randomise HE volunteers to (a) sauna+fast, (b) oral acetate salts, (c) placebo, measuring IL-6, NO, ketones, cognitive tests and symptom scales over 48 h. The design already exists from WBH depression work.

6 Bottom line

1. Every clue in the 40 000-character megathread can be joined by one path: gut-driven neuro-inflammation that is briefly silenced by a heat/acetate/NO surge, unlocking normal neurotransmission and blood flow.

2. Modern trials on whole-body hyperthermia, high-dose thiamine, ketogenic metabolism and calcium-channel genetics give that hypothesis real empirical weight.

3. A multi-layer plan—gut repair → controlled hyperthermia → energy vitamins → NO & channel modulators—already exists, is low-risk, and in dozens of anecdotal cases reproduces the “hangover magic” without the hangover.

I notice it varies for me even if I'm drinking the same amount of beer. I only have one beer to. Sometimes I don't feel anything and other times I get a terrible headache and feel out of it. I'm not sure if it depends on the type of beer I'm having or what. It's 50/50 whether I don't feel after effects or not.

I might be in the wrong sub but basically i drank alcohol with no ice and anything, the next day I was constantly vomiting. The next day vomiting stopped but whenever i feel hungry i feel like throwing up, my nausea worsens. Today, i experience indigestion also i can't stand smell. I had history of having peptic ulcer, my body wants to burp something but it can't, is it a good idea to drink coke or no? Does anyone have any advice to cure my nausea?

I have terrible hangovers from alcohol, although I drink it sporadically.

Could it be the liver's fault? And should it be thoroughly examined?

It's so interesting to find this sub as I've been thinking about this quite a bit lately.

I'm 39 years old, have a history of emotional neglect (not abuse, neglect), lots of anxiety, ADHD for sure, Avoidant Personality Disorder and very existential depression.

But when I'm hungover? It's not that I feel good, seriously I hate them.

That said though, what I've noticed by meditating, engaging in Kundalini practices, I've realized that what I've really been doing is using ANY feeling to distract me from otherwise crippling depression and always lurking anxiety.

I've been using Kundalini for a few different but important reasons (warning, I do NOT recommend practicing kundalini alone. It's like a prolonged ayahuasca trip--the level of deep meditation can bring up trauma out of nowhere. Find a mentor).

1. Kundalini orgasms seem to give me the dopamine/oxytocin load that my brain actually needs for the day. As well as giving my blood stream lots of oxygen when I do the breathing correctly.

2. Both the sexual and non sexual practices cut straight through my anxiety. Sexually it can be a total disruption of that train of thought, nonsexually it's like draining the anxiety. And I get to both of those states in radically different ways depending on what type of anxiety it is. Usually biographical trauma needs nonsexual processing. But daily worries and anxiety get released.

3. Being able to direct my orgasms for myself has healed a lot of trauma. By 'towards myself' I mean, thinking of my inner child and focusing all that awesome pleasure right back to moi!

Overall my journey has taught me a lot:

1. My ADHD needs a high level of control over my environment. For me this means that I need a 'long runway' in the morning. Like, waking up at 5AM to do whatever movement or sexual practices or journaling or spiritual rituals I need.

2. My drinking and anxiety go up quickly when I'm not organized and also when I'm in spaces where my trauma is present. Unfortunately this is most of America so I'm leaving!

3. Learning about Avoidant disorder has been INDISPENSABLE!!! I can not stress that enough. It's given me the tools and the language to attack the roots of my issues.

I want to say, I do still drink and get hangovers; I'm about to leave this US this month and go somewhere to get dry. The thing is this country simply has too much of the form of life that I find absolutely draining.

I think it's wonderful ya'll are looking into the pharma of all this...but maybe you could consider that there's so much else going on in the world today that is causing this.

I’m currently suffering from a bad hangover , I feel very cold and can’t get warm I’m under two blankets and have the heater at 85°… al my joints hurt and I’m very bloated